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Results: 1 to 20 of 84

1.

Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis.

Vyas D, Laput G, Vyas AK.

Onco Targets Ther. 2014 Jun 12;7:1015-23. doi: 10.2147/OTT.S60114. eCollection 2014. Review.

PMID:
24959088
[PubMed]
Free PMC Article
2.

Valproic acid overcomes transforming growth factor-β-mediated sorafenib resistance in hepatocellular carcinoma.

Matsuda Y, Wakai T, Kubota M, Osawa M, Hirose Y, Sakata J, Kobayashi T, Fujimaki S, Takamura M, Yamagiwa S, Aoyagi Y.

Int J Clin Exp Pathol. 2014 Mar 15;7(4):1299-313. eCollection 2014.

PMID:
24817927
[PubMed - in process]
Free PMC Article
3.

p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage.

Cam M, Bid HK, Xiao L, Zambetti GP, Houghton PJ, Cam H.

J Biol Chem. 2014 Feb 14;289(7):4083-94. doi: 10.1074/jbc.M113.530303. Epub 2013 Dec 23.

PMID:
24366874
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Age-dependent decline in EGF-induced signaling is independent of intracellular thiols.

Palmer HJ, Tuzon CT, Paulson KE.

Age (Omaha). 1999 Oct;22(4):167-73. doi: 10.1007/s11357-999-0019-y.

PMID:
23604425
[PubMed]
Free PMC Article
5.

MEK-1 activates C-Raf through a Ras-independent mechanism.

Leicht DT, Balan V, Zhu J, Kaplun A, Bronisz A, Rana A, Tzivion G.

Biochim Biophys Acta. 2013 May;1833(5):976-86. doi: 10.1016/j.bbamcr.2013.01.015. Epub 2013 Jan 27.

PMID:
23360980
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Grb2, a double-edged sword of receptor tyrosine kinase signaling.

Belov AA, Mohammadi M.

Sci Signal. 2012 Nov 6;5(249):pe49. doi: 10.1126/scisignal.2003576. Review.

PMID:
23131845
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Current understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor design.

Ray S, Liu M.

Future Med Chem. 2012 Sep;4(13):1701-13. doi: 10.4155/fmc.12.110. Review.

PMID:
22924508
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A simple matter of life and death-the trials of postnatal Beta-cell mass regulation.

Tarabra E, Pelengaris S, Khan M.

Int J Endocrinol. 2012;2012:516718. doi: 10.1155/2012/516718. Epub 2012 Apr 22.

PMID:
22577380
[PubMed]
Free PMC Article
9.

Regulation of pancreatic cancer growth by superoxide.

Du J, Nelson ES, Simons AL, Olney KE, Moser JC, Schrock HE, Wagner BA, Buettner GR, Smith BJ, Teoh ML, Tsao MS, Cullen JJ.

Mol Carcinog. 2013 Jul;52(7):555-67. doi: 10.1002/mc.21891. Epub 2012 Mar 5.

PMID:
22392697
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Activation kinetics of RAF protein in the ternary complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis.

Hibino K, Shibata T, Yanagida T, Sako Y.

J Biol Chem. 2011 Oct 21;286(42):36460-8. doi: 10.1074/jbc.M111.262675. Epub 2011 Aug 23.

PMID:
21862573
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons.

Khasnavis S, Pahan K.

J Neuroimmune Pharmacol. 2012 Jun;7(2):424-35. doi: 10.1007/s11481-011-9286-3. Epub 2011 Jun 24.

PMID:
21701815
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15.

Kaoud TS, Devkota AK, Harris R, Rana MS, Abramczyk O, Warthaka M, Lee S, Girvin ME, Riggs AF, Dalby KN.

Biochemistry. 2011 May 31;50(21):4568-78. doi: 10.1021/bi200202y. Epub 2011 May 4.

PMID:
21506533
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A RasGTP-induced conformational change in C-RAF is essential for accurate molecular recognition.

Hibino K, Shibata T, Yanagida T, Sako Y.

Biophys J. 2009 Sep 2;97(5):1277-87. doi: 10.1016/j.bpj.2009.05.048.

PMID:
19720015
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Raf kinases: function, regulation and role in human cancer.

Leicht DT, Balan V, Kaplun A, Singh-Gupta V, Kaplun L, Dobson M, Tzivion G.

Biochim Biophys Acta. 2007 Aug;1773(8):1196-212. Epub 2007 May 22. Review.

PMID:
17555829
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MAP kinase pathways: the first twenty years.

Avruch J.

Biochim Biophys Acta. 2007 Aug;1773(8):1150-60. Epub 2006 Nov 15. Review.

PMID:
17229475
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.

Terai K, Matsuda M.

EMBO J. 2006 Aug 9;25(15):3556-64. Epub 2006 Jul 20.

PMID:
16858395
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase.

Balan V, Leicht DT, Zhu J, Balan K, Kaplun A, Singh-Gupta V, Qin J, Ruan H, Comb MJ, Tzivion G.

Mol Biol Cell. 2006 Mar;17(3):1141-53. Epub 2006 Jan 11.

PMID:
16407412
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Quantitative model of Ras-phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly.

Kaur H, Park CS, Lewis JM, Haugh JM.

Biochem J. 2006 Jan 1;393(Pt 1):235-43.

PMID:
16159314
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding.

Zhu J, Balan V, Bronisz A, Balan K, Sun H, Leicht DT, Luo Z, Qin J, Avruch J, Tzivion G.

Mol Biol Cell. 2005 Oct;16(10):4733-44. Epub 2005 Aug 10.

PMID:
16093354
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Neuronal death/survival signaling pathways in cerebral ischemia.

Sugawara T, Fujimura M, Noshita N, Kim GW, Saito A, Hayashi T, Narasimhan P, Maier CM, Chan PH.

NeuroRx. 2004 Jan;1(1):17-25. Review.

PMID:
15717004
[PubMed - indexed for MEDLINE]
Free PMC Article

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