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Items: 10


Correlation of decreased expression of PHLDA1 protein with malignant phenotype of gastric adenocarcinoma.

Zhao P, Lu Y, Liu L.

Int J Clin Exp Pathol. 2015 May 1;8(5):5230-5. eCollection 2015.


Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.

Pillai VB, Sundaresan NR, Gupta MP.

Circ Res. 2014 Jan 17;114(2):368-78. doi: 10.1161/CIRCRESAHA.113.300536. Review.


Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis.

Hodakoski C, Hopkins BD, Barrows D, Mense SM, Keniry M, Anderson KE, Kern PA, Hawkins PT, Stephens LR, Parsons R.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):155-60. doi: 10.1073/pnas.1213773111. Epub 2013 Dec 23.


Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.

Ben-Aissa K, Patino-Lopez G, Belkina NV, Maniti O, Rosales T, Hao JJ, Kruhlak MJ, Knutson JR, Picart C, Shaw S.

J Biol Chem. 2012 May 11;287(20):16311-23. doi: 10.1074/jbc.M111.304881. Epub 2012 Mar 20.


Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH).

Patino-Lopez G, Aravind L, Dong X, Kruhlak MJ, Ostap EM, Shaw S.

J Biol Chem. 2010 Mar 19;285(12):8675-86. doi: 10.1074/jbc.M109.086959. Epub 2010 Jan 12.


Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans.

Van Wesenbeeck L, Odgren PR, Coxon FP, Frattini A, Moens P, Perdu B, MacKay CA, Van Hul E, Timmermans JP, Vanhoenacker F, Jacobs R, Peruzzi B, Teti A, Helfrich MH, Rogers MJ, Villa A, Van Hul W.

J Clin Invest. 2007 Apr;117(4):919-30.


The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation.

Baba K, Takeshita A, Majima K, Ueda R, Kondo S, Juni N, Yamamoto D.

Mol Cell Biol. 1999 Jun;19(6):4405-13.


Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.

Andjelković M, Jakubowicz T, Cron P, Ming XF, Han JW, Hemmings BA.

Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5699-704.


Structure of the binding site for inositol phosphates in a PH domain.

Hyvönen M, Macias MJ, Nilges M, Oschkinat H, Saraste M, Wilmanns M.

EMBO J. 1995 Oct 2;14(19):4676-85.

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