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α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.

Choi JI, Wang C, Thomas MJ, Pitt GS.

PLoS One. 2016 Mar 30;11(3):e0152355. doi: 10.1371/journal.pone.0152355. eCollection 2016.


Identification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6.

Ali SR, Singh AK, Laezza F.

J Biol Chem. 2016 May 20;291(21):11268-84. doi: 10.1074/jbc.M115.703868. Epub 2016 Mar 18.


Effects of Amiodarone and N-desethylamiodarone on Cardiac Voltage-Gated Sodium Channels.

Ghovanloo MR, Abdelsayed M, Ruben PC.

Front Pharmacol. 2016 Mar 1;7:39. doi: 10.3389/fphar.2016.00039. eCollection 2016.


Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3.

Mazzanti A, Maragna R, Faragli A, Monteforte N, Bloise R, Memmi M, Novelli V, Baiardi P, Bagnardi V, Etheridge SP, Napolitano C, Priori SG.

J Am Coll Cardiol. 2016 Mar 8;67(9):1053-8. doi: 10.1016/j.jacc.2015.12.033.


Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm.

Zhou J, Wang L, Zuo M, Wang X, Ahmed AS, Chen Q, Wang QK.

Sci Rep. 2016 Feb 23;6:21538. doi: 10.1038/srep21538.


Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison.

Loussouarn G, Sternberg D, Nicole S, Marionneau C, Le Bouffant F, Toumaniantz G, Barc J, Malak OA, Fressart V, Péréon Y, Baró I, Charpentier F.

Front Pharmacol. 2016 Jan 14;6:314. doi: 10.3389/fphar.2015.00314. eCollection 2015. Review.


Predicting drug-induced QT prolongation and torsades de pointes.

Roden DM.

J Physiol. 2016 May 1;594(9):2459-68. doi: 10.1113/JP270526. Epub 2016 Jan 18.


Evaluation of the Genetic Basis of Familial Aggregation of Pacemaker Implantation by a Large Next Generation Sequencing Panel.

Celestino-Soper PB, Doytchinova A, Steiner HA, Uradu A, Lynnes TC, Groh WJ, Miller JM, Lin H, Gao H, Wang Z, Liu Y, Chen PS, Vatta M.

PLoS One. 2015 Dec 4;10(12):e0143588. doi: 10.1371/journal.pone.0143588. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0147455.


Genetics of inherited primary arrhythmia disorders.

Spears DA, Gollob MH.

Appl Clin Genet. 2015 Sep 18;8:215-33. doi: 10.2147/TACG.S55762. eCollection 2015. Review.


Voltage-gated sodium channels and cancer: is excitability their primary role?

Roger S, Gillet L, Le Guennec JY, Besson P.

Front Pharmacol. 2015 Jul 29;6:152. doi: 10.3389/fphar.2015.00152. eCollection 2015. Review.


Post-transcriptional regulation of cardiac sodium channel gene SCN5A expression and function by miR-192-5p.

Zhao Y, Huang Y, Li W, Wang Z, Zhan S, Zhou M, Yao Y, Zeng Z, Hou Y, Chen Q, Tu X, Wang QK, Huang Z.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2024-34. doi: 10.1016/j.bbadis.2015.07.016. Epub 2015 Jul 21.


Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?

Ebert AD, Diecke S, Chen IY, Wu JC.

EMBO Mol Med. 2015 Jul 16;7(9):1090-103. doi: 10.15252/emmm.201504395. Review.


Ion Channels in the Heart.

Bartos DC, Grandi E, Ripplinger CM.

Compr Physiol. 2015 Jul 1;5(3):1423-64. doi: 10.1002/cphy.c140069. Review.


Arrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Intracellular Acidosis.

Hu RM, Tan BH, Tester DJ, Song C, He Y, Dovat S, Peterson BZ, Ackerman MJ, Makielski JC.

PLoS One. 2015 Apr 29;10(4):e0124921. doi: 10.1371/journal.pone.0124921. eCollection 2015.


Enhanced Classification of Brugada Syndrome-Associated and Long-QT Syndrome-Associated Genetic Variants in the SCN5A-Encoded Na(v)1.5 Cardiac Sodium Channel.

Kapplinger JD, Giudicessi JR, Ye D, Tester DJ, Callis TE, Valdivia CR, Makielski JC, Wilde AA, Ackerman MJ.

Circ Cardiovasc Genet. 2015 Aug;8(4):582-95. doi: 10.1161/CIRCGENETICS.114.000831. Epub 2015 Apr 22.


Protein assemblies of sodium and inward rectifier potassium channels control cardiac excitability and arrhythmogenesis.

Willis BC, Ponce-Balbuena D, Jalife J.

Am J Physiol Heart Circ Physiol. 2015 Jun 15;308(12):H1463-73. doi: 10.1152/ajpheart.00176.2015. Epub 2015 Apr 10. Review.


Channelopathies - emerging trends in the management of inherited arrhythmias.

Chockalingam P, Mizusawa Y, Wilde AA.

Indian Pacing Electrophysiol J. 2015 Apr 1;15(1):43-54. eCollection 2015 Jan-Feb. Review.


Deranged sodium to sudden death.

Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, Qu Z, Rajamani S, Rippinger CM, Sejersted OM, O'Rourke B, Weiss JN, Varró A, Zaza A.

J Physiol. 2015 Mar 15;593(6):1331-45. doi: 10.1113/jphysiol.2014.281204. Review. Erratum in: J Physiol. 2016 Mar 15;594(6):1791.


Synchronous systolic subcellular Ca2+-elevations underlie ventricular arrhythmia in drug-induced long QT type 2.

Kim JJ, Němec J, Li Q, Salama G.

Circ Arrhythm Electrophysiol. 2015 Jun;8(3):703-12. doi: 10.1161/CIRCEP.114.002214. Epub 2015 Feb 26. Erratum in: Circ Arrhythm Electrophysiol. 2015 Aug;8(4):998.


Defective fast inactivation recovery of Nav 1.4 in congenital myasthenic syndrome.

Arnold WD, Feldman DH, Ramirez S, He L, Kassar D, Quick A, Klassen TL, Lara M, Nguyen J, Kissel JT, Lossin C, Maselli RA.

Ann Neurol. 2015 May;77(5):840-50. doi: 10.1002/ana.24389. Epub 2015 Mar 27.

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