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Items: 1 to 20 of 36


The Role of Crk Adaptor Proteins in T-Cell Adhesion and Migration.

Braiman A, Isakov N.

Front Immunol. 2015 Oct 5;6:509. doi: 10.3389/fimmu.2015.00509. eCollection 2015. Review.


Biosensor architectures for high-fidelity reporting of cellular signaling.

Dushek O, Lellouch AC, Vaux DJ, Shahrezaei V.

Biophys J. 2014 Aug 5;107(3):773-82. doi: 10.1016/j.bpj.2014.06.021.


Molecular dynamics of the proline switch and its role in Crk signaling.

Xia J, Levy RM.

J Phys Chem B. 2014 May 1;118(17):4535-45. doi: 10.1021/jp5013297. Epub 2014 Apr 16.


Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector.

Nieto-Pelegrin E, Meiler E, Martín-Villa JM, Benito-León M, Martinez-Quiles N.

PLoS Pathog. 2014 Mar 27;10(3):e1004022. doi: 10.1371/journal.ppat.1004022. eCollection 2014 Mar.


The adaptor protein Crk in immune response.

Liu D.

Immunol Cell Biol. 2014 Jan;92(1):80-9. doi: 10.1038/icb.2013.64. Epub 2013 Oct 29. Review.


Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis.

Bolduc D, Rahdar M, Tu-Sekine B, Sivakumaren SC, Raben D, Amzel LM, Devreotes P, Gabelli SB, Cole P.

Elife. 2013 Jul 9;2:e00691. doi: 10.7554/eLife.00691.


Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

Kurokawa M, Ito T, Yang CS, Zhao C, Macintyre AN, Rizzieri DA, Rathmell JC, Deininger MW, Reya T, Kornbluth S.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2300-5. doi: 10.1073/pnas.1206551110. Epub 2013 Jan 16.


Models of crk adaptor proteins in cancer.

Bell ES, Park M.

Genes Cancer. 2012 May;3(5-6):341-52. doi: 10.1177/1947601912459951.


Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytes.

Whitney NP, Lamb AC, Louw TM, Subramanian A.

Ultrasound Med Biol. 2012 Oct;38(10):1734-43. doi: 10.1016/j.ultrasmedbio.2012.06.002. Epub 2012 Aug 21.


Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.

Sato M, Maruoka M, Takeya T.

J Signal Transduct. 2012;2012:414913. doi: 10.1155/2012/414913. Epub 2012 May 17.


Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII.

Jankowski W, Saleh T, Pai MT, Sriram G, Birge RB, Kalodimos CG.

Nat Chem Biol. 2012 May 13;8(6):590-6. doi: 10.1038/nchembio.954.


Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomics.

Ferrando IM, Chaerkady R, Zhong J, Molina H, Jacob HK, Herbst-Robinson K, Dancy BM, Katju V, Bose R, Zhang J, Pandey A, Cole PA.

Mol Cell Proteomics. 2012 Aug;11(8):355-69. doi: 10.1074/mcp.M111.015750. Epub 2012 Apr 12.


Emerging roles for crk in human cancer.

Sriram G, Birge RB.

Genes Cancer. 2010 Nov;1(11):1132-9. doi: 10.1177/1947601910397188.


The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edge.

He Y, Kapoor A, Cook S, Liu S, Xiang Y, Rao CV, Kenis PJ, Wang F.

J Cell Sci. 2011 Jul 1;124(Pt 13):2153-64. doi: 10.1242/jcs.078535. Epub 2011 May 31.


Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation.

Sriram G, Reichman C, Tunceroglu A, Kaushal N, Saleh T, Machida K, Mayer B, Ge Q, Li J, Hornbeck P, Kalodimos CG, Birge RB.

Oncogene. 2011 Nov 17;30(46):4645-55. doi: 10.1038/onc.2011.170. Epub 2011 May 23.


Structural basis for regulation of the Crk signaling protein by a proline switch.

Sarkar P, Saleh T, Tzeng SR, Birge RB, Kalodimos CG.

Nat Chem Biol. 2011 Jan;7(1):51-7. doi: 10.1038/nchembio.494. Epub 2010 Dec 5.


Real-time fluorescent resonance energy transfer analysis to monitor drug resistance in chronic myelogenous leukemia.

Tunceroglu A, Matsuda M, Birge RB.

Mol Cancer Ther. 2010 Nov;9(11):3065-73. doi: 10.1158/1535-7163.MCT-10-0623. Epub 2010 Sep 3.


The switchable integrin adhesome.

Zaidel-Bar R, Geiger B.

J Cell Sci. 2010 May 1;123(Pt 9):1385-8. doi: 10.1242/jcs.066183. Review. No abstract available.


Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts.

Bradley WD, Koleske AJ.

J Cell Sci. 2009 Oct 1;122(Pt 19):3441-54. doi: 10.1242/jcs.039859.


Crk and CrkL adaptor proteins: networks for physiological and pathological signaling.

Birge RB, Kalodimos C, Inagaki F, Tanaka S.

Cell Commun Signal. 2009 May 10;7:13. doi: 10.1186/1478-811X-7-13.

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