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Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S.

Oncotarget. 2016 Apr 19;7(16):22883-92. doi: 10.18632/oncotarget.8256.


Development and characterization of a new human hepatic cell line.

Ramboer E, De Craene B, De Kock J, Berx G, Rogiers V, Vanhaecke T, Vinken M.

EXCLI J. 2015 Jul 28;14:875-89. doi: 10.17179/excli2015-424. eCollection 2015.


Immortalized Human Hepatic Cell Lines for In Vitro Testing and Research Purposes.

Ramboer E, Vanhaecke T, Rogiers V, Vinken M.

Methods Mol Biol. 2015;1250:53-76. doi: 10.1007/978-1-4939-2074-7_4.


Comparison of human Nrf2 antibodies: A tale of two proteins.

Kemmerer ZA, Ader NR, Mulroy SS, Eggler AL.

Toxicol Lett. 2015 Oct 14;238(2):83-9. doi: 10.1016/j.toxlet.2015.07.004. Epub 2015 Jul 26.


Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice.

Okada H, Honda M, Campbell JS, Takegoshi K, Sakai Y, Yamashita T, Shirasaki T, Takabatake R, Nakamura M, Tanaka T, Kaneko S.

Cancer Sci. 2015 Sep;106(9):1143-52. doi: 10.1111/cas.12730. Epub 2015 Sep 1.


Flow Cytometry Based Detection and Isolation of Plasmodium falciparum Liver Stages In Vitro.

Dumoulin PC, Trop SA, Ma J, Zhang H, Sherman MA, Levitskaya J.

PLoS One. 2015 Jun 12;10(6):e0129623. doi: 10.1371/journal.pone.0129623. eCollection 2015.


Hepatotoxic potential of asarones: in vitro evaluation of hepatotoxicity and quantitative determination in herbal products.

Patel DN, Ho HK, Tan LL, Tan MM, Zhang Q, Low MY, Chan CL, Koh HL.

Front Pharmacol. 2015 Feb 20;6:25. doi: 10.3389/fphar.2015.00025. eCollection 2015.


Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models.

Tan CY, Lai RC, Wong W, Dan YY, Lim SK, Ho HK.

Stem Cell Res Ther. 2014 Jun 10;5(3):76. doi: 10.1186/scrt465.


Strategies for immortalization of primary hepatocytes.

Ramboer E, De Craene B, De Kock J, Vanhaecke T, Berx G, Rogiers V, Vinken M.

J Hepatol. 2014 Oct;61(4):925-43. doi: 10.1016/j.jhep.2014.05.046. Epub 2014 Jun 6. Review.


High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening.

Kwon SJ, Lee DW, Shah DA, Ku B, Jeon SY, Solanki K, Ryan JD, Clark DS, Dordick JS, Lee MY.

Nat Commun. 2014 May 6;5:3739. doi: 10.1038/ncomms4739.


Up-regulating CYP3A4 expression in C3A cells by transfection with a novel chimeric regulator of hPXR-p53-AD.

Chen F, Rao XH, Yang JL, Pan MX, Gao Y, Li ZL, Li Y, Zhu YF, Wang Y.

PLoS One. 2014 May 1;9(5):e95752. doi: 10.1371/journal.pone.0095752. eCollection 2014.


Toxicological evaluation of a rotenone derivative in rodents for clinical myocardial perfusion imaging.

Fernando P, Yan X, Lockwood J, Duan Y, Wei L, Glenn Wells R, Bensimon C, Mullett WM, Ruddy T.

Cardiovasc Toxicol. 2014 Jun;14(2):170-82. doi: 10.1007/s12012-013-9241-z.


Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG.

Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Review.


Human hepatocyte carcinogenesis (review).

Shiraha H, Yamamoto K, Namba M.

Int J Oncol. 2013 Apr;42(4):1133-8. doi: 10.3892/ijo.2013.1829. Epub 2013 Feb 19. Review.


Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells.

Cuconati A, Mills C, Goddard C, Zhang X, Yu W, Guo H, Xu X, Block TM.

PLoS One. 2013;8(1):e54595. doi: 10.1371/journal.pone.0054595. Epub 2013 Jan 23.


Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?

Kia R, Sison RL, Heslop J, Kitteringham NR, Hanley N, Mills JS, Park BK, Goldring CE.

Br J Clin Pharmacol. 2013 Apr;75(4):885-96. doi: 10.1111/j.1365-2125.2012.04360.x. Review.


The immortalisation of rat hepatocytes by transfection with SV40 sequences.

Macdonald C, Willett B.

Cytotechnology. 1997 Jan;23(1-3):161-70. doi: 10.1023/A:1007907416596.


Monoclonal antibodies reveal multiple forms of expression of human microsomal epoxide hydrolase.

Duan H, Takagi A, Kayano H, Koyama I, Morisseau C, Hammock BD, Akatsuka T.

Toxicol Appl Pharmacol. 2012 Apr 1;260(1):27-34. doi: 10.1016/j.taap.2012.01.021. Epub 2012 Jan 28.

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