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Erroneous Silencing of the Mitotic Checkpoint by Aberrant Spindle Pole-Kinetochore Coordination.

Chen J, Liu J.

Biophys J. 2015 Dec 1;109(11):2418-35. doi: 10.1016/j.bpj.2015.10.024.


Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint.

Etemad B, Kuijt TE, Kops GJ.

Nat Commun. 2015 Dec 1;6:8987. doi: 10.1038/ncomms9987.


Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells.

Tauchman EC, Boehm FJ, DeLuca JG.

Nat Commun. 2015 Dec 1;6:10036. doi: 10.1038/ncomms10036.


The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling.

Krenn V, Musacchio A.

Front Oncol. 2015 Oct 16;5:225. doi: 10.3389/fonc.2015.00225. eCollection 2015. Review.


Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy.

Bennett A, Bechi B, Tighe A, Thompson S, Procter DJ, Taylor SS.

Oncotarget. 2015 Aug 28;6(25):20921-32.


Predictive and prognostic values of BubR1 and synuclein-gamma expression in breast cancer.

Cirak Y, Furuncuoglu Y, Yapicier O, Alici S, Argon A.

Int J Clin Exp Pathol. 2015 May 1;8(5):5345-53. eCollection 2015.


The equatorial position of the metaphase plate ensures symmetric cell divisions.

Tan CH, Gasic I, Huber-Reggi SP, Dudka D, Barisic M, Maiato H, Meraldi P.

Elife. 2015 Jul 18;4. doi: 10.7554/eLife.05124.


An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes.

Metchat A, Eguren M, Hossain JM, Politi AZ, Huet S, Ellenberg J.

Nat Commun. 2015 Jul 15;6:7784. doi: 10.1038/ncomms8784. Retraction in: Nat Commun. 2015;6:8124.


Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment.

Krefman NI, Drubin DG, Barnes G.

Mol Biol Cell. 2015 Jul 15;26(14):2620-39. doi: 10.1091/mbc.E15-05-0276. Epub 2015 May 28.


Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores.

Kim S, Yu H.

J Cell Biol. 2015 Jan 19;208(2):181-96. doi: 10.1083/jcb.201407074.


The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C.

Izawa D, Pines J.

Nature. 2015 Jan 29;517(7536):631-4. doi: 10.1038/nature13911. Epub 2014 Nov 12.


Signalling dynamics in the spindle checkpoint response.

London N, Biggins S.

Nat Rev Mol Cell Biol. 2014 Nov;15(11):736-47. doi: 10.1038/nrm3888. Epub 2014 Oct 10. Review.


Characterization of ring-like F-actin structure as a mechanical partner for spindle positioning in mitosis.

Lu H, Zhao Q, Jiang H, Zhu T, Xia P, Seffens W, Aikhionbare F, Wang D, Dou Z, Yao X.

PLoS One. 2014 Oct 9;9(10):e102547. doi: 10.1371/journal.pone.0102547. eCollection 2014.


Co-activator independent differences in how the metaphase and anaphase APC/C recognise the same substrate.

Matsusaka T, Enquist-Newman M, Morgan DO, Pines J.

Biol Open. 2014 Sep 12;3(10):904-12. doi: 10.1242/bio.20149415.


Spatial-temporal model for silencing of the mitotic spindle assembly checkpoint.

Chen J, Liu J.

Nat Commun. 2014 Sep 12;5:4795. doi: 10.1038/ncomms5795.


Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

Foijer F, Xie SZ, Simon JE, Bakker PL, Conte N, Davis SH, Kregel E, Jonkers J, Bradley A, Sorger PK.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13427-32. doi: 10.1073/pnas.1400892111. Epub 2014 Sep 2.


Tethering sister centromeres to each other suggests the spindle checkpoint detects stretch within the kinetochore.

Nannas NJ, Murray AW.

PLoS Genet. 2014 Aug 7;10(8):e1004492. doi: 10.1371/journal.pgen.1004492. eCollection 2014 Aug.


The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.

Britigan EM, Wan J, Zasadil LM, Ryan SD, Weaver BA.

Mol Biol Cell. 2014 Sep 15;25(18):2761-73. doi: 10.1091/mbc.E14-05-0966. Epub 2014 Jul 23.


Direct kinetochore-spindle pole connections are not required for chromosome segregation.

Sikirzhytski V, Magidson V, Steinman JB, He J, Le Berre M, Tikhonenko I, Ault JG, McEwen BF, Chen JK, Sui H, Piel M, Kapoor TM, Khodjakov A.

J Cell Biol. 2014 Jul 21;206(2):231-43. doi: 10.1083/jcb.201401090. Epub 2014 Jul 14.


An overview of the spindle assembly checkpoint status in oral cancer.

Teixeira JH, Silva PM, Reis RM, Moura IM, Marques S, Fonseca J, Monteiro LS, Bousbaa H.

Biomed Res Int. 2014;2014:145289. doi: 10.1155/2014/145289. Epub 2014 Jun 3. Review.

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