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Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes.

Hulot JS, Stillitano F, Salem JE, Kovacic JC, Fuster V, Hajjar RJ.

Stem Cell Res Ther. 2014 Jan 9;5(1):1. doi: 10.1186/scrt390. Review.


Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models.

Larochelle A, Dunbar CE.

Semin Hematol. 2013 Apr;50(2):101-30. Review. No abstract available.


Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer.

Ozturk F, Park PJ, Tellez J, Colletti E, Eiden MV, Almeida-Porada G, Porada CD.

J Gene Med. 2012 Mar;14(3):169-81. doi: 10.1002/jgm.2607.


RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.

Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG.

EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285.


Contributions of gene marking to cell and gene therapies.

Barese CN, Dunbar CE.

Hum Gene Ther. 2011 Jun;22(6):659-68. doi: 10.1089/hum.2010.237. Epub 2011 May 5. Review.


Lentiviral vectors in gene therapy: their current status and future potential.

Escors D, Breckpot K.

Arch Immunol Ther Exp (Warsz). 2010 Apr;58(2):107-19. doi: 10.1007/s00005-010-0063-4. Epub 2010 Feb 9. Review.


Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.

Zhao H, Pestina TI, Nasimuzzaman M, Mehta P, Hargrove PW, Persons DA.

Blood. 2009 Jun 4;113(23):5747-56. doi: 10.1182/blood-2008-10-186684. Epub 2009 Apr 13.


Lentiviral transduction of apoAI into hematopoietic progenitor cells and macrophages: applications to cell therapy of atherosclerosis.

Su YR, Blakemore JL, Zhang Y, Linton MF, Fazio S.

Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1439-46. doi: 10.1161/ATVBAHA.107.160093. Epub 2008 May 22.


Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection.

Milsom MD, Williams DA.

DNA Repair (Amst). 2007 Aug 1;6(8):1210-21. Epub 2007 May 7. Review.


In vitro culture during retroviral transduction improves thymic repopulation and output after total body irradiation and autologous peripheral blood progenitor cell transplantation in rhesus macaques.

Loré K, Seggewiss R, Guenaga FJ, Pittaluga S, Donahue RE, Krouse A, Metzger ME, Koup RA, Reilly C, Douek DC, Dunbar CE.

Stem Cells. 2006 Jun;24(6):1539-48. Epub 2006 Feb 23.


Mobilization as a preparative regimen for hematopoietic stem cell transplantation.

Chen J, Larochelle A, Fricker S, Bridger G, Dunbar CE, Abkowitz JL.

Blood. 2006 May 1;107(9):3764-71. Epub 2006 Jan 26.


Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes.

Lucas ML, Seidel NE, Porada CD, Quigley JG, Anderson SM, Malech HL, Abkowitz JL, Zanjani ED, Bodine DM.

Blood. 2005 Jul 1;106(1):51-8. Epub 2005 Mar 17.


Differential regulation of the human and murine CD34 genes in hematopoietic stem cells.

Okuno Y, Iwasaki H, Huettner CS, Radomska HS, Gonzalez DA, Tenen DG, Akashi K.

Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6246-51.


Transplantable hematopoietic stem cells in human fetal liver have a CD34(+) side population (SP)phenotype.

Uchida N, Fujisaki T, Eaves AC, Eaves CJ.

J Clin Invest. 2001 Oct;108(7):1071-7.


Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates.

Takatoku M, Sellers S, Agricola BA, Metzger ME, Kato I, Donahue RE, Dunbar CE.

J Clin Invest. 2001 Aug;108(3):447-55.


Lentivirus vector-mediated hematopoietic stem cell gene transfer of common gamma-chain cytokine receptor in rhesus macaques.

An DS, Kung SK, Bonifacino A, Wersto RP, Metzger ME, Agricola BA, Mao SH, Chen IS, Donahue RE.

J Virol. 2001 Apr;75(8):3547-55.


HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV replication and cell death.

Brodie SJ, Patterson BK, Lewinsohn DA, Diem K, Spach D, Greenberg PD, Riddell SR, Corey L.

J Clin Invest. 2000 May;105(10):1407-17. Retraction in: J Clin Invest. 2010 Sep;120(9):3401.


Gene therapy for the hemoglobin disorders: past, present, and future.

Persons DA, Nienhuis AW.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5022-4. Review. No abstract available.


Marking and gene expression by a lentivirus vector in transplanted human and nonhuman primate CD34(+) cells.

An DS, Wersto RP, Agricola BA, Metzger ME, Lu S, Amado RG, Chen IS, Donahue RE.

J Virol. 2000 Feb;74(3):1286-95.

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