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Items: 1 to 20 of 173


Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications.

Quintanal-Villalonga A, Paz-Ares L, Ferrer I, Molina-Pinelo S.

Dis Markers. 2016;2016:9214056. doi: 10.1155/2016/9214056. Epub 2016 Jul 26. Review.


MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.

Shelby SJ, Feathers KL, Ganios AM, Jia L, Miller JM, Thompson DA.

Exp Eye Res. 2015 Nov;140:28-40. doi: 10.1016/j.exer.2015.08.006. Epub 2015 Aug 15.


Targeting Protein Kinase C Downstream of Growth Factor and Adhesion Signalling.

Dowling CM, Kiely PA.

Cancers (Basel). 2015 Jul 15;7(3):1271-91. doi: 10.3390/cancers7030836. Review.


Tag7 (PGLYRP1) in Complex with Hsp70 Induces Alternative Cytotoxic Processes in Tumor Cells via TNFR1 Receptor.

Yashin DV, Ivanova OK, Soshnikova NV, Sheludchenkov AA, Romanova EA, Dukhanina EA, Tonevitsky AG, Gnuchev NV, Gabibov AG, Georgiev GP, Sashchenko LP.

J Biol Chem. 2015 Aug 28;290(35):21724-31. doi: 10.1074/jbc.M115.639732. Epub 2015 Jul 16.


Receptor tyrosine kinases: legacy of the first two decades.

Schlessinger J.

Cold Spring Harb Perspect Biol. 2014 Mar 1;6(3). pii: a008912. doi: 10.1101/cshperspect.a008912. Review.


Phosphoinositides: tiny lipids with giant impact on cell regulation.

Balla T.

Physiol Rev. 2013 Jul;93(3):1019-137. doi: 10.1152/physrev.00028.2012. Review.


EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells.

Abhold EL, Kiang A, Rahimy E, Kuo SZ, Wang-Rodriguez J, Lopez JP, Blair KJ, Yu MA, Haas M, Brumund KT, Altuna X, Patel A, Weisman RA, Ongkeko WM.

PLoS One. 2012;7(2):e32459. doi: 10.1371/journal.pone.0032459. Epub 2012 Feb 27.


Membrane depolarization increases membrane PtdIns(4,5)P2 levels through mechanisms involving PKC βII and PI4 kinase.

Chen X, Zhang X, Jia C, Xu J, Gao H, Zhang G, Du X, Zhang H.

J Biol Chem. 2011 Nov 18;286(46):39760-7. doi: 10.1074/jbc.M111.289090. Epub 2011 Sep 27.


Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition.

Tang QY, Zhang Z, Xia J, Ren D, Logothetis DE.

J Biol Chem. 2010 Jun 18;285(25):19259-66. doi: 10.1074/jbc.M109.100156. Epub 2010 Apr 14.


Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition.

Wang J, Peng Q, Lin Q, Childress C, Carey D, Yang W.

J Biol Chem. 2010 Apr 16;285(16):12279-88. doi: 10.1074/jbc.M109.086405. Epub 2010 Feb 19.


Phospholipase C-delta extends intercellular signalling range and responses to injury-released growth factors in non-excitable cells.

Mi LY, Ettenson DS, Edelman ER.

Cell Prolif. 2008 Aug;41(4):671-90. doi: 10.1111/j.1365-2184.2008.00544.x. Epub 2008 Jun 19.


Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.

Galisteo ML, Yang Y, Ureña J, Schlessinger J.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9796-801. Epub 2006 Jun 15.


Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factor.

Wang Y, Wu J, Wang Z.

Mol Biol Cell. 2006 May;17(5):2267-77. Epub 2006 Mar 8.


Activation of EGF receptor kinase by L1-mediated homophilic cell interactions.

Islam R, Kristiansen LV, Romani S, Garcia-Alonso L, Hortsch M.

Mol Biol Cell. 2004 Apr;15(4):2003-12. Epub 2004 Jan 12.


The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease.

Hunter T.

Philos Trans R Soc Lond B Biol Sci. 1998 Apr 29;353(1368):583-605. Review.


Requirement for phospholipase C-gamma1 enzymatic activity in growth factor-induced mitogenesis.

Wang Z, Glück S, Zhang L, Moran MF.

Mol Cell Biol. 1998 Jan;18(1):590-7.


On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins.

Birnbaumer L, Zhu X, Jiang M, Boulay G, Peyton M, Vannier B, Brown D, Platano D, Sadeghi H, Stefani E, Birnbaumer M.

Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15195-202. Review.

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