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Results: 15

1.

Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins.

Mattoo RU, Goloubinoff P.

Cell Mol Life Sci. 2014 Sep;71(17):3311-25. doi: 10.1007/s00018-014-1627-y. Epub 2014 Apr 24.

PMID:
24760129
[PubMed - in process]
Free PMC Article
2.

Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies.

Ebrahimi-Fakhari D, Saidi LJ, Wahlster L.

Acta Neuropathol Commun. 2013 Dec 5;1(1):79. doi: 10.1186/2051-5960-1-79.

PMID:
24314025
[PubMed - in process]
Free PMC Article
3.

Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model.

Cushman-Nick M, Bonini NM, Shorter J.

PLoS Genet. 2013;9(9):e1003781. doi: 10.1371/journal.pgen.1003781. Epub 2013 Sep 5.

PMID:
24039611
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Life cycle of cytosolic prions.

Hofmann J, Vorberg I.

Prion. 2013 Sep-Oct;7(5):369-77. doi: 10.4161/pri.26414. Epub 2013 Sep 10. Review.

PMID:
24021964
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Aging, protein aggregation, chaperones, and neurodegenerative disorders: mechanisms of coupling and therapeutic opportunities.

Cohen E.

Rambam Maimonides Med J. 2012 Oct 31;3(4):e0021. doi: 10.5041/RMMJ.10088. Print 2012 Oct.

PMID:
23908845
[PubMed]
Free PMC Article
6.

Mutational analysis of Sse1 (Hsp110) suggests an integral role for this chaperone in yeast prion propagation in vivo.

Moran C, Kinsella GK, Zhang ZR, Perrett S, Jones GW.

G3 (Bethesda). 2013 Aug 7;3(8):1409-18. doi: 10.1534/g3.113.007112.

PMID:
23797105
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.

Kurnellas MP, Adams CM, Sobel RA, Steinman L, Rothbard JB.

Sci Transl Med. 2013 Apr 3;5(179):179ra42. doi: 10.1126/scitranslmed.3005681.

PMID:
23552370
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Chaperones: needed for both the good times and the bad times.

Quinlan RA, Ellis RJ.

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 25;368(1617):20130091. doi: 10.1098/rstb.2013.0091. Print 2013 May 5.

PMID:
23530265
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mechanism of an ATP-independent protein disaggregase: I. structure of a membrane protein aggregate reveals a mechanism of recognition by its chaperone.

Nguyen TX, Jaru-Ampornpan P, Lam VQ, Cao P, Piszkiewicz S, Hess S, Shan SO.

J Biol Chem. 2013 May 10;288(19):13420-30. doi: 10.1074/jbc.M113.462812. Epub 2013 Mar 22.

PMID:
23525109
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Aggregation of human S100A8 and S100A9 amyloidogenic proteins perturbs proteostasis in a yeast model.

Eremenko E, Ben-Zvi A, Morozova-Roche LA, Raveh D.

PLoS One. 2013;8(3):e58218. doi: 10.1371/journal.pone.0058218. Epub 2013 Mar 6.

PMID:
23483999
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Aging and the aggregating proteome.

David DC.

Front Genet. 2012 Nov 20;3:247. doi: 10.3389/fgene.2012.00247. eCollection 2012.

PMID:
23181070
[PubMed]
Free PMC Article
12.

Hsp104 drives "protein-only" positive selection of Sup35 prion strains encoding strong [PSI(+)].

DeSantis ME, Shorter J.

Chem Biol. 2012 Nov 21;19(11):1400-10. doi: 10.1016/j.chembiol.2012.09.013.

PMID:
23177195
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cellular strategies for regulating functional and nonfunctional protein aggregation.

Gsponer J, Babu MM.

Cell Rep. 2012 Nov 29;2(5):1425-37. doi: 10.1016/j.celrep.2012.09.036. Epub 2012 Nov 15.

PMID:
23168257
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients.

DeSantis ME, Leung EH, Sweeny EA, Jackrel ME, Cushman-Nick M, Neuhaus-Follini A, Vashist S, Sochor MA, Knight MN, Shorter J.

Cell. 2012 Nov 9;151(4):778-93. doi: 10.1016/j.cell.2012.09.038.

PMID:
23141537
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular mechanisms of spatial protein quality control.

Alberti S.

Prion. 2012 Nov-Dec;6(5):437-42. doi: 10.4161/pri.22470. Epub 2012 Oct 10.

PMID:
23051707
[PubMed - indexed for MEDLINE]
Free PMC Article

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