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Items: 1 to 20 of 107

1.

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits.

Ulirsch JC, Nandakumar SK, Wang L, Giani FC, Zhang X, Rogov P, Melnikov A, McDonel P, Do R, Mikkelsen TS, Sankaran VG.

Cell. 2016 Jun 2;165(6):1530-45. doi: 10.1016/j.cell.2016.04.048.

PMID:
27259154
2.

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay.

Tewhey R, Kotliar D, Park DS, Liu B, Winnicki S, Reilly SK, Andersen KG, Mikkelsen TS, Lander ES, Schaffner SF, Sabeti PC.

Cell. 2016 Jun 2;165(6):1519-29. doi: 10.1016/j.cell.2016.04.027.

PMID:
27259153
3.

Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks.

Kelley DR, Snoek J, Rinn JL.

Genome Res. 2016 Jul;26(7):990-9. doi: 10.1101/gr.200535.115. Epub 2016 May 3.

4.

Interactions between pluripotency factors specify cis-regulation in embryonic stem cells.

Fiore C, Cohen BA.

Genome Res. 2016 Jun;26(6):778-86. doi: 10.1101/gr.200733.115. Epub 2016 Apr 15.

PMID:
27197208
5.

Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.

Verfaillie A, Svetlichnyy D, Imrichova H, Davie K, Fiers M, Kalender Atak Z, Hulselmans G, Christiaens V, Aerts S.

Genome Res. 2016 Jul;26(7):882-95. doi: 10.1101/gr.204149.116. Epub 2016 May 18.

6.

Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo.

Sayal R, Dresch JM, Pushel I, Taylor BR, Arnosti DN.

Elife. 2016 May 6;5. pii: e08445. doi: 10.7554/eLife.08445.

7.

Strategies for targeting primate neural circuits with viral vectors.

El-Shamayleh Y, Ni AM, Horwitz GD.

J Neurophysiol. 2016 Jul 1;116(1):122-34. doi: 10.1152/jn.00087.2016. Epub 2016 Apr 6. Review.

PMID:
27052579
8.

Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations.

Peterman N, Levine E.

BMC Genomics. 2016 Mar 9;17:206. doi: 10.1186/s12864-016-2533-5.

9.

Comprehensive Analysis of the SUL1 Promoter of Saccharomyces cerevisiae.

Rich MS, Payen C, Rubin AF, Ong GT, Sanchez MR, Yachie N, Dunham MJ, Fields S.

Genetics. 2016 May;203(1):191-202. doi: 10.1534/genetics.116.188037. Epub 2016 Mar 2.

PMID:
26936925
10.

A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening.

Diao Y, Li B, Meng Z, Jung I, Lee AY, Dixon J, Maliskova L, Guan KL, Shen Y, Ren B.

Genome Res. 2016 Mar;26(3):397-405. doi: 10.1101/gr.197152.115. Epub 2016 Jan 26.

PMID:
26813977
11.

Contrasting Frequencies and Effects of cis- and trans-Regulatory Mutations Affecting Gene Expression.

Metzger BP, Duveau F, Yuan DC, Tryban S, Yang B, Wittkopp PJ.

Mol Biol Evol. 2016 May;33(5):1131-46. doi: 10.1093/molbev/msw011. Epub 2016 Jan 18.

PMID:
26782996
12.

Common variation in atrial fibrillation: navigating the path from genetic association to mechanism.

Tucker NR, Clauss S, Ellinor PT.

Cardiovasc Res. 2016 Apr 1;109(4):493-501. doi: 10.1093/cvr/cvv283. Epub 2016 Jan 4. Review.

PMID:
26733238
13.

Genome-wide identification of hypoxia-induced enhancer regions.

Kamps-Hughes N, Preston JL, Randel MA, Johnson EA.

PeerJ. 2015 Dec 21;3:e1527. doi: 10.7717/peerj.1527. eCollection 2015.

14.

Compensatory Drift and the Evolutionary Dynamics of Dosage-Sensitive Duplicate Genes.

Thompson A, Zakon HH, Kirkpatrick M.

Genetics. 2016 Feb;202(2):765-74. doi: 10.1534/genetics.115.178137. Epub 2015 Dec 12.

PMID:
26661114
15.

Massively Systematic Transcript End Readout, "MASTER": Transcription Start Site Selection, Transcriptional Slippage, and Transcript Yields.

Vvedenskaya IO, Zhang Y, Goldman SR, Valenti A, Visone V, Taylor DM, Ebright RH, Nickels BE.

Mol Cell. 2015 Dec 17;60(6):953-65. doi: 10.1016/j.molcel.2015.10.029. Epub 2015 Nov 25.

PMID:
26626484
16.

Advanced Applications of RNA Sequencing and Challenges.

Han Y, Gao S, Muegge K, Zhang W, Zhou B.

Bioinform Biol Insights. 2015 Nov 15;9(Suppl 1):29-46. doi: 10.4137/BBI.S28991. eCollection 2015. Review.

17.

Platform for high-throughput antibody selection using synthetically-designed antibody libraries.

Batonick M, Holland EG, Busygina V, Alderman D, Kay BK, Weiner MP, Kiss MM.

N Biotechnol. 2016 Sep 25;33(5 Pt A):565-73. doi: 10.1016/j.nbt.2015.11.005. Epub 2015 Nov 24.

PMID:
26607994
18.

Epistatic Interactions in the Arabinose Cis-Regulatory Element.

Lagator M, Igler C, Moreno AB, Guet CC, Bollback JP.

Mol Biol Evol. 2016 Mar;33(3):761-9. doi: 10.1093/molbev/msv269. Epub 2015 Nov 20.

19.

Massively parallel cis-regulatory analysis in the mammalian central nervous system.

Shen SQ, Myers CA, Hughes AE, Byrne LC, Flannery JG, Corbo JC.

Genome Res. 2016 Feb;26(2):238-55. doi: 10.1101/gr.193789.115. Epub 2015 Nov 17.

20.

Uncovering drug-responsive regulatory elements.

Luizon MR, Ahituv N.

Pharmacogenomics. 2015 Nov;16(16):1829-41. doi: 10.2217/pgs.15.121. Epub 2015 Nov 10.

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