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Items: 1 to 20 of 35


The Extended Family of CD1d-Restricted NKT Cells: Sifting through a Mixed Bag of TCRs, Antigens, and Functions.

Macho-Fernandez E, Brigl M.

Front Immunol. 2015 Jul 28;6:362. doi: 10.3389/fimmu.2015.00362. eCollection 2015. Review.


Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition.

Rödström KE, Regenthal P, Lindkvist-Petersson K.

PLoS One. 2015 Jul 6;10(7):e0131988. doi: 10.1371/journal.pone.0131988. eCollection 2015.


Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.

Motozono C, Pearson JA, De Leenheer E, Rizkallah PJ, Beck K, Trimby A, Sewell AK, Wong FS, Cole DK.

J Biol Chem. 2015 Jul 31;290(31):18924-33. doi: 10.1074/jbc.M114.622522. Epub 2015 Jun 17.


Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.

Osinski T, Pomés A, Majorek KA, Glesner J, Offermann LR, Vailes LD, Chapman MD, Minor W, Chruszcz M.

J Immunol. 2015 Jul 1;195(1):307-16. doi: 10.4049/jimmunol.1402199. Epub 2015 May 29.


T cells in the control of organ-specific autoimmunity.

Bluestone JA, Bour-Jordan H, Cheng M, Anderson M.

J Clin Invest. 2015 Jun;125(6):2250-60. doi: 10.1172/JCI78089. Epub 2015 May 18. Review.


The T cell antigen receptor: the Swiss army knife of the immune system.

Attaf M, Legut M, Cole DK, Sewell AK.

Clin Exp Immunol. 2015 Jul;181(1):1-18. doi: 10.1111/cei.12622. Epub 2015 May 14. Review.


The first step of peptide selection in antigen presentation by MHC class I molecules.

Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, Hoppes R, Stadnik M, Janssen L, Ovaa H, van Veelen PA, Perrakis A, Neefjes J.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1505-10. doi: 10.1073/pnas.1416543112. Epub 2015 Jan 20.


Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.

Madura F, Rizkallah PJ, Holland CJ, Fuller A, Bulek A, Godkin AJ, Schauenburg AJ, Cole DK, Sewell AK.

Eur J Immunol. 2015 Feb;45(2):584-91. doi: 10.1002/eji.201445114. Epub 2014 Dec 28.


Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.

Tungatt K, Bianchi V, Crowther MD, Powell WE, Schauenburg AJ, Trimby A, Donia M, Miles JJ, Holland CJ, Cole DK, Godkin AJ, Peakman M, Straten PT, Svane IM, Sewell AK, Dolton G.

J Immunol. 2015 Jan 1;194(1):463-74. doi: 10.4049/jimmunol.1401785. Epub 2014 Dec 1.


Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells.

Ziegler S, Skibbe K, Walker A, Ke X, Heinemann FM, Heinold A, Mok JY, van Esch WJ, Yang D, Wölfl M, Timm J.

J Virol. 2014 Oct;88(19):11080-90. doi: 10.1128/JVI.01590-14. Epub 2014 Jul 9.


Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity.

Stadinski BD, Trenh P, Duke B, Huseby PG, Li G, Stern LJ, Huseby ES.

J Immunol. 2014 Jun 15;192(12):6071-82. doi: 10.4049/jimmunol.1303209. Epub 2014 May 9.


Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells.

Dolton G, Lissina A, Skowera A, Ladell K, Tungatt K, Jones E, Kronenberg-Versteeg D, Akpovwa H, Pentier JM, Holland CJ, Godkin AJ, Cole DK, Neller MA, Miles JJ, Price DA, Peakman M, Sewell AK.

Clin Exp Immunol. 2014 Jul;177(1):47-63. doi: 10.1111/cei.12339.


Advances in the cellular immunological pathogenesis of type 1 diabetes.

Li M, Song LJ, Qin XY.

J Cell Mol Med. 2014 May;18(5):749-58. doi: 10.1111/jcmm.12270. Epub 2014 Mar 14. Review.


A mathematical model of immune activation with a unified self-nonself concept.

Khailaie S, Bahrami F, Janahmadi M, Milanez-Almeida P, Huehn J, Meyer-Hermann M.

Front Immunol. 2013 Dec 26;4:474. doi: 10.3389/fimmu.2013.00474. eCollection 2013.


The versatility of the αβ T-cell antigen receptor.

Bhati M, Cole DK, McCluskey J, Sewell AK, Rossjohn J.

Protein Sci. 2014 Mar;23(3):260-72. doi: 10.1002/pro.2412. Epub 2014 Jan 28. Review.


Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop.

Sethi DK, Gordo S, Schubert DA, Wucherpfennig KW.

Nat Commun. 2013;4:2623. doi: 10.1038/ncomms3623.


Intravenous immunoglobulin modulates the expansion and cytotoxicity of CD8+ T cells.

Trépanier P, Chabot D, Bazin R.

Immunology. 2014 Feb;141(2):233-41. doi: 10.1111/imm.12189.


Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets.

Kanatsuna N, Taneera J, Vaziri-Sani F, Wierup N, Larsson HE, Delli A, Skärstrand H, Balhuizen A, Bennet H, Steiner DF, Törn C, Fex M, Lernmark Å.

J Biol Chem. 2013 Oct 4;288(40):29013-23. doi: 10.1074/jbc.M113.478222. Epub 2013 Aug 9.


Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode.

Cole DK, Sami M, Scott DR, Rizkallah PJ, Borbulevych OY, Todorov PT, Moysey RK, Jakobsen BK, Boulter JM, Baker BM, Yi Li.

Front Immunol. 2013 Jun 26;4:168. doi: 10.3389/fimmu.2013.00168. eCollection 2013.


Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.

Graham KL, Sutherland RM, Mannering SI, Zhao Y, Chee J, Krishnamurthy B, Thomas HE, Lew AM, Kay TW.

Rev Diabet Stud. 2012 Winter;9(4):148-68. doi: 10.1900/RDS.2012.9.148. Epub 2012 Dec 28. Review.

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