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Results: 16

Cited In for PubMed (Select 21873373)


Predicting the future: opportunities and challenges for the chemical industry to apply 21st-century toxicity testing.

Settivari RS, Ball N, Murphy L, Rasoulpour R, Boverhof DR, Carney EW.

J Am Assoc Lab Anim Sci. 2015;54(2):214-23.


International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.

Bal-Price A, Crofton KM, Leist M, Allen S, Arand M, Buetler T, Delrue N, FitzGerald RE, Hartung T, Heinonen T, Hogberg H, Bennekou SH, Lichtensteiger W, Oggier D, Paparella M, Axelstad M, Piersma A, Rached E, Schilter B, Schmuck G, Stoppini L, Tongiorgi E, Tiramani M, Monnet-Tschudi F, Wilks MF, Ylikomi T, Fritsche E.

Arch Toxicol. 2015 Feb;89(2):269-87. doi: 10.1007/s00204-015-1464-2. Epub 2015 Jan 25.


Big data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicants.

Zhu H, Zhang J, Kim MT, Boison A, Sedykh A, Moran K.

Chem Res Toxicol. 2014 Oct 20;27(10):1643-51. doi: 10.1021/tx500145h. Epub 2014 Sep 16.


From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.

Balmer NV, Klima S, Rempel E, Ivanova VN, Kolde R, Weng MK, Meganathan K, Henry M, Sachinidis A, Berthold MR, Hengstler JG, Rahnenf├╝hrer J, Waldmann T, Leist M.

Arch Toxicol. 2014 Jul;88(7):1451-68. doi: 10.1007/s00204-014-1279-6. Epub 2014 Jun 17.


Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery.

Zimmer B, Pallocca G, Dreser N, Foerster S, Waldmann T, Westerhout J, Julien S, Krause KH, van Thriel C, Hengstler JG, Sachinidis A, Bosgra S, Leist M.

Arch Toxicol. 2014 May;88(5):1109-26. doi: 10.1007/s00204-014-1231-9. Epub 2014 Apr 2.


A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment.

Nel AE, Nasser E, Godwin H, Avery D, Bahadori T, Bergeson L, Beryt E, Bonner JC, Boverhof D, Carter J, Castranova V, Deshazo JR, Hussain SM, Kane AB, Klaessig F, Kuempel E, Lafranconi M, Landsiedel R, Malloy T, Miller MB, Morris J, Moss K, Oberdorster G, Pinkerton K, Pleus RC, Shatkin JA, Thomas R, Tolaymat T, Wang A, Wong J.

ACS Nano. 2013 Aug 27;7(8):6422-33. doi: 10.1021/nn4037927. Epub 2013 Aug 7.


Advancing human health risk assessment: integrating recent advisory committee recommendations.

Dourson M, Becker RA, Haber LT, Pottenger LH, Bredfeldt T, Fenner-Crisp PA.

Crit Rev Toxicol. 2013 Jul;43(6):467-92. doi: 10.3109/10408444.2013.807223. Review.


Current perspectives on the use of alternative species in human health and ecological hazard assessments.

Perkins EJ, Ankley GT, Crofton KM, Garcia-Reyero N, LaLone CA, Johnson MS, Tietge JE, Villeneuve DL.

Environ Health Perspect. 2013 Sep;121(9):1002-10. doi: 10.1289/ehp.1306638. Epub 2013 Jun 12. Review.


The Tox21 robotic platform for the assessment of environmental chemicals--from vision to reality.

Attene-Ramos MS, Miller N, Huang R, Michael S, Itkin M, Kavlock RJ, Austin CP, Shinn P, Simeonov A, Tice RR, Xia M.

Drug Discov Today. 2013 Aug;18(15-16):716-23. doi: 10.1016/j.drudis.2013.05.015. Epub 2013 May 31. Review.


Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.

Sipes NS, Martin MT, Kothiya P, Reif DM, Judson RS, Richard AM, Houck KA, Dix DJ, Kavlock RJ, Knudsen TB.

Chem Res Toxicol. 2013 Jun 17;26(6):878-95. doi: 10.1021/tx400021f. Epub 2013 May 16.


Improving the human hazard characterization of chemicals: a Tox21 update.

Tice RR, Austin CP, Kavlock RJ, Bucher JR.

Environ Health Perspect. 2013 Jul;121(7):756-65. doi: 10.1289/ehp.1205784. Epub 2013 Apr 18. Review.


A computational model predicting disruption of blood vessel development.

Kleinstreuer N, Dix D, Rountree M, Baker N, Sipes N, Reif D, Spencer R, Knudsen T.

PLoS Comput Biol. 2013 Apr;9(4):e1002996. doi: 10.1371/journal.pcbi.1002996. Epub 2013 Apr 4.


Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.

Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, Baird WM.

Toxicol Appl Pharmacol. 2013 Mar 1;267(2):192-9. doi: 10.1016/j.taap.2012.12.011. Epub 2012 Dec 27.


Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System.

Judson RS, Martin MT, Egeghy P, Gangwal S, Reif DM, Kothiya P, Wolf M, Cathey T, Transue T, Smith D, Vail J, Frame A, Mosher S, Cohen Hubal EA, Richard AM.

Int J Mol Sci. 2012;13(2):1805-31. doi: 10.3390/ijms13021805. Epub 2012 Feb 9.


Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data.

Rusyn I, Sedykh A, Low Y, Guyton KZ, Tropsha A.

Toxicol Sci. 2012 May;127(1):1-9. doi: 10.1093/toxsci/kfs095. Epub 2012 Mar 2.


Environmental impact on vascular development predicted by high-throughput screening.

Kleinstreuer NC, Judson RS, Reif DM, Sipes NS, Singh AV, Chandler KJ, Dewoskin R, Dix DJ, Kavlock RJ, Knudsen TB.

Environ Health Perspect. 2011 Nov;119(11):1596-603. doi: 10.1289/ehp.1103412. Epub 2011 Jul 25.

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