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Items: 1 to 20 of 24

1.

The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events.

Nuche-Berenguer B, Ramos-Álvarez I, Jensen RT.

Biochim Biophys Acta. 2016 Jun;1862(6):1122-36. doi: 10.1016/j.bbadis.2016.02.008. Epub 2016 Feb 18.

PMID:
26912410
2.

Protein Kinase D Enzymes as Regulators of EMT and Cancer Cell Invasion.

Durand N, Borges S, Storz P.

J Clin Med. 2016 Feb 3;5(2). pii: E20. doi: 10.3390/jcm5020020. Review.

3.

The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma.

Döppler H, Bastea L, Borges S, Geiger X, Storz P.

Oncotarget. 2015 Oct 6;6(30):29740-52. doi: 10.18632/oncotarget.4965.

4.

Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.

Durand N, Borges S, Storz P.

Cell Mol Life Sci. 2015 Nov;72(22):4369-82. doi: 10.1007/s00018-015-2011-2. Epub 2015 Aug 8. Review.

PMID:
26253275
5.

GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis.

Xu X, Gera N, Li H, Yun M, Zhang L, Wang Y, Wang QJ, Jin T.

Mol Biol Cell. 2015 Mar 1;26(5):874-86. doi: 10.1091/mbc.E14-05-0982. Epub 2015 Jan 7.

6.

Increasing radiosensitivity with the downregulation of cofilin-1 in U251 human glioma cells.

Du HQ, Chen L, Wang Y, Wang LJ, Yan H, Liu HY, Xiao H.

Mol Med Rep. 2015 May;11(5):3354-60. doi: 10.3892/mmr.2014.3125. Epub 2014 Dec 22.

7.

Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks.

Navarro MN, Goebel J, Hukelmann JL, Cantrell DA.

Mol Cell Proteomics. 2014 Dec;13(12):3544-57. doi: 10.1074/mcp.M113.037242. Epub 2014 Sep 29.

8.

Protein kinase d isoforms differentially modulate cofilin-driven directed cell migration.

Döppler H, Bastea LI, Borges S, Spratley SJ, Pearce SE, Storz P.

PLoS One. 2014 May 19;9(5):e98090. doi: 10.1371/journal.pone.0098090. eCollection 2014.

9.

A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells.

Borges S, Döppler HR, Storz P.

Breast Cancer Res Treat. 2014 Feb;144(1):79-91. doi: 10.1007/s10549-014-2857-2. Epub 2014 Feb 8.

10.

Regulation of VASP by phosphorylation: consequences for cell migration.

Döppler H, Storz P.

Cell Adh Migr. 2013 Nov-Dec;7(6):482-6. doi: 10.4161/cam.27351. Epub 2013 Dec 5.

11.

PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart.

Xiang SY, Ouyang K, Yung BS, Miyamoto S, Smrcka AV, Chen J, Heller Brown J.

Sci Signal. 2013 Dec 17;6(306):ra108. doi: 10.1126/scisignal.2004405.

12.

Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.

Borges S, Döppler H, Perez EA, Andorfer CA, Sun Z, Anastasiadis PZ, Thompson E, Geiger XJ, Storz P.

Breast Cancer Res. 2013 Aug 23;15(2):R66. doi: 10.1186/bcr3460.

13.

Protein kinase D1-mediated phosphorylations regulate vasodilator-stimulated phosphoprotein (VASP) localization and cell migration.

Döppler HR, Bastea LI, Lewis-Tuffin LJ, Anastasiadis PZ, Storz P.

J Biol Chem. 2013 Aug 23;288(34):24382-93. doi: 10.1074/jbc.M113.474676. Epub 2013 Jul 11.

14.

Protein kinase D-mediated phosphorylation at Ser99 regulates localization of p21-activated kinase 4.

Bastea LI, Döppler H, Pearce SE, Durand N, Spratley SJ, Storz P.

Biochem J. 2013 Oct 15;455(2):251-60. doi: 10.1042/BJ20130281.

15.

Functions of cofilin in cell locomotion and invasion.

Bravo-Cordero JJ, Magalhaes MA, Eddy RJ, Hodgson L, Condeelis J.

Nat Rev Mol Cell Biol. 2013 Jul;14(7):405-15. doi: 10.1038/nrm3609. Epub 2013 Jun 19. Review.

16.

Mathematical modeling of sustainable synaptogenesis by repetitive stimuli suggests signaling mechanisms in vivo.

Takizawa H, Hiroi N, Funahashi A.

PLoS One. 2012;7(12):e51000. doi: 10.1371/journal.pone.0051000. Epub 2012 Dec 20.

17.

PKD controls mitotic Golgi complex fragmentation through a Raf-MEK1 pathway.

Kienzle C, Eisler SA, Villeneuve J, Brummer T, Olayioye MA, Hausser A.

Mol Biol Cell. 2013 Feb;24(3):222-33. doi: 10.1091/mbc.E12-03-0198. Epub 2012 Dec 14.

18.

Neuregulin mediates F-actin-driven cell migration through inhibition of protein kinase D1 via Rac1 protein.

Döppler H, Bastea LI, Eiseler T, Storz P.

J Biol Chem. 2013 Jan 4;288(1):455-65. doi: 10.1074/jbc.M112.397448. Epub 2012 Nov 12.

19.

Principles of branch dynamics governing shape characteristics of cerebellar Purkinje cell dendrites.

Fujishima K, Horie R, Mochizuki A, Kengaku M.

Development. 2012 Sep;139(18):3442-55. doi: 10.1242/dev.081315.

20.

GIT1 phosphorylation on serine 46 by PKD3 regulates paxillin trafficking and cellular protrusive activity.

Huck B, Kemkemer R, Franz-Wachtel M, Macek B, Hausser A, Olayioye MA.

J Biol Chem. 2012 Oct 5;287(41):34604-13. doi: 10.1074/jbc.M112.374652. Epub 2012 Aug 13.

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