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Results: 14

1.

Inhibition of notch signaling in combination with Paclitaxel reduces platinum-resistant ovarian tumor growth.

Groeneweg JW, DiGloria CM, Yuan J, Richardson WS, Growdon WB, Sathyanarayanan S, Foster R, Rueda BR.

Front Oncol. 2014 Jul 7;4:171. doi: 10.3389/fonc.2014.00171. eCollection 2014.

PMID:
25072022
[PubMed]
Free PMC Article
2.

Cancer stem cells in glioma: challenges and opportunities.

Wang J, Ma Y, Cooper MK.

Transl Cancer Res. 2013 Oct 1;2(5):429-441.

PMID:
24634854
[PubMed]
Free PMC Article
3.

Notch signalling in adult neurons: a potential target for microtubule stabilization.

Bonini SA, Ferrari-Toninelli G, Montinaro M, Memo M.

Ther Adv Neurol Disord. 2013 Nov;6(6):375-85. doi: 10.1177/1756285613490051.

PMID:
24228073
[PubMed]
Free PMC Article
4.

Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition.

Espinoza I, Pochampally R, Xing F, Watabe K, Miele L.

Onco Targets Ther. 2013 Sep 6;6:1249-59. doi: 10.2147/OTT.S36162. Review.

PMID:
24043949
[PubMed]
Free PMC Article
5.

Notch inhibitors for cancer treatment.

Espinoza I, Miele L.

Pharmacol Ther. 2013 Aug;139(2):95-110. doi: 10.1016/j.pharmthera.2013.02.003. Epub 2013 Feb 28. Review.

PMID:
23458608
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors.

Schott AF, Landis MD, Dontu G, Griffith KA, Layman RM, Krop I, Paskett LA, Wong H, Dobrolecki LE, Lewis MT, Froehlich AM, Paranilam J, Hayes DF, Wicha MS, Chang JC.

Clin Cancer Res. 2013 Mar 15;19(6):1512-24. doi: 10.1158/1078-0432.CCR-11-3326. Epub 2013 Jan 22.

PMID:
23340294
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Bone sarcomas: from biology to targeted therapies.

Gaspar N, Di Giannatale A, Geoerger B, Redini F, Corradini N, Enz-Werle N, Tirode F, Marec-Berard P, Gentet JC, Laurence V, Piperno-Neumann S, Oberlin O, Brugieres L.

Sarcoma. 2012;2012:301975. doi: 10.1155/2012/301975. Epub 2012 Nov 27.

PMID:
23226965
[PubMed]
Free PMC Article
8.

Optimizing drug development of anti-cancer drugs in children using modelling and simulation.

van Hasselt JG, van Eijkelenburg NK, Beijnen JH, Schellens JH, Huitema AD.

Br J Clin Pharmacol. 2013 Jul;76(1):30-47. doi: 10.1111/bcp.12062. Review.

PMID:
23216601
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Notch signaling in pediatric soft tissue sarcomas.

Rota R, Ciarapica R, Miele L, Locatelli F.

BMC Med. 2012 Nov 16;10:141. doi: 10.1186/1741-7015-10-141. Review.

PMID:
23158439
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Molecular pathways: context-dependent approaches to Notch targeting as cancer therapy.

Egloff AM, Grandis JR.

Clin Cancer Res. 2012 Oct 1;18(19):5188-95. doi: 10.1158/1078-0432.CCR-11-2258. Epub 2012 Jul 6.

PMID:
22773520
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models.

Mizuma M, Rasheed ZA, Yabuuchi S, Omura N, Campbell NR, de Wilde RF, De Oliveira E, Zhang Q, Puig O, Matsui W, Hidalgo M, Maitra A, Rajeshkumar NV.

Mol Cancer Ther. 2012 Sep;11(9):1999-2009. doi: 10.1158/1535-7163.MCT-12-0017. Epub 2012 Jul 2.

PMID:
22752426
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma.

Andolfo I, Liguori L, De Antonellis P, Cusanelli E, Marinaro F, Pistollato F, Garzia L, De Vita G, Petrosino G, Accordi B, Migliorati R, Basso G, Iolascon A, Cinalli G, Zollo M.

Neuro Oncol. 2012 May;14(5):596-612. doi: 10.1093/neuonc/nos002. Epub 2012 Mar 12.

PMID:
22411914
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Myc proteins in brain tumor development and maintenance.

Swartling FJ.

Ups J Med Sci. 2012 May;117(2):122-31. doi: 10.3109/03009734.2012.658975. Epub 2012 Feb 21.

PMID:
22348395
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.

Groth C, Fortini ME.

Semin Cell Dev Biol. 2012 Jun;23(4):465-72. doi: 10.1016/j.semcdb.2012.01.016. Epub 2012 Jan 30. Review.

PMID:
22309842
[PubMed - indexed for MEDLINE]
Free PMC Article

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