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Results: 1 to 20 of 33

Cited In for PubMed (Select 21789790)


Isoform switch of pyruvate kinase m1 indeed occurs but not to pyruvate kinase m2 in human tumorigenesis.

Zhan C, Yan L, Wang L, Ma J, Jiang W, Zhang Y, Shi Y, Wang Q.

PLoS One. 2015 Mar 4;10(3):e0118663. doi: 10.1371/journal.pone.0118663. eCollection 2015.


Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.

Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Sugiyama T, Futamura M, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.

Sci Rep. 2015 Feb 27;5:8647. doi: 10.1038/srep08647.


Synergistic combination of gemcitabine and dietary molecule induces apoptosis in pancreatic cancer cells and down regulates PKM2 expression.

Pandita A, Kumar B, Manvati S, Vaishnavi S, Singh SK, Bamezai RN.

PLoS One. 2014 Sep 8;9(9):e107154. doi: 10.1371/journal.pone.0107154. eCollection 2014.


From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.

Bathe OF, Farshidfar F.

Genes (Basel). 2014 Jul 22;5(3):536-60. doi: 10.3390/genes5030536.


Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis.

Grüning NM, Du D, Keller MA, Luisi BF, Ralser M.

Open Biol. 2014 Mar 5;4:130232. doi: 10.1098/rsob.130232.


Geroncogenesis: metabolic changes during aging as a driver of tumorigenesis.

Wu LE, Gomes AP, Sinclair DA.

Cancer Cell. 2014 Jan 13;25(1):12-9. doi: 10.1016/j.ccr.2013.12.005.


Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.

Onodera Y, Nam JM, Bissell MJ.

J Clin Invest. 2014 Jan;124(1):367-84. doi: 10.1172/JCI63146. Epub 2013 Dec 9.


Stress eating and tuning out: cancer cells re-wire metabolism to counter stress.

Stine ZE, Dang CV.

Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):609-19. doi: 10.3109/10409238.2013.844093. Epub 2013 Oct 7. Review.


Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.

Desai S, Ding M, Wang B, Lu Z, Zhao Q, Shaw K, Yung WK, Weinstein JN, Tan M, Yao J.

Oncotarget. 2014 Sep 30;5(18):8202-10.


Secreted human adipose leptin decreases mitochondrial respiration in HCT116 colon cancer cells.

Yehuda-Shnaidman E, Nimri L, Tarnovscki T, Kirshtein B, Rudich A, Schwartz B.

PLoS One. 2013 Sep 20;8(9):e74843. doi: 10.1371/journal.pone.0074843. eCollection 2013.


Nuclear PKM2 regulates the Warburg effect.

Yang W, Lu Z.

Cell Cycle. 2013 Oct 1;12(19):3154-8. doi: 10.4161/cc.26182. Epub 2013 Aug 26.


Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab.

Chimenti MS, Tucci P, Candi E, Perricone R, Melino G, Willis AE.

Cell Cycle. 2013 Sep 15;12(18):3025-36. doi: 10.4161/cc.26067. Epub 2013 Aug 19.


Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator.

Filipp FV.

J Carcinog. 2013 Jul 24;12:14. doi: 10.4103/1477-3163.115423. eCollection 2013.


Epithelial cancers in the post-genomic era: should we reconsider our lifestyle?

Holly JM, Zeng L, Perks CM.

Cancer Metastasis Rev. 2013 Dec;32(3-4):673-705. doi: 10.1007/s10555-013-9445-5. Review.


Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.

Iqbal MA, Siddiqui FA, Gupta V, Chattopadhyay S, Gopinath P, Kumar B, Manvati S, Chaman N, Bamezai RN.

Mol Cancer. 2013 Jul 9;12:72. doi: 10.1186/1476-4598-12-72.


M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation.

Morgan HP, O'Reilly FJ, Wear MA, O'Neill JR, Fothergill-Gilmore LA, Hupp T, Walkinshaw MD.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5881-6. doi: 10.1073/pnas.1217157110. Epub 2013 Mar 25.


PKM2, a Central Point of Regulation in Cancer Metabolism.

Wong N, De Melo J, Tang D.

Int J Cell Biol. 2013;2013:242513. doi: 10.1155/2013/242513. Epub 2013 Feb 14.


Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.

Mukherjee J, Phillips JJ, Zheng S, Wiencke J, Ronen SM, Pieper RO.

PLoS One. 2013;8(2):e57610. doi: 10.1371/journal.pone.0057610. Epub 2013 Feb 25.


Tumor-specific isoform switch of the fibroblast growth factor receptor 2 underlies the mesenchymal and malignant phenotypes of clear cell renal cell carcinomas.

Zhao Q, Caballero OL, Davis ID, Jonasch E, Tamboli P, Yung WK, Weinstein JN; Kenna Shaw for TCGA research network, Strausberg RL, Yao J.

Clin Cancer Res. 2013 May 1;19(9):2460-72. doi: 10.1158/1078-0432.CCR-12-3708. Epub 2013 Feb 26.


Recent discoveries in the cycling, growing and aging of the p53 field.

McCubrey JA, Demidenko ZN.

Aging (Albany NY). 2012 Dec;4(12):887-93. Review.

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