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Items: 1 to 20 of 227

1.

Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype.

Sun WY, Kim HM, Jung WH, Koo JS.

J Transl Med. 2016 Jun 8;14(1):168. doi: 10.1186/s12967-016-0915-8.

2.

Increased Expression of PHGDH and Prognostic Significance in Colorectal Cancer.

Jia XQ, Zhang S, Zhu HJ, Wang W, Zhu JH, Wang XD, Qiang JF.

Transl Oncol. 2016 Jun;9(3):191-6. doi: 10.1016/j.tranon.2016.03.006. Epub 2016 May 10.

3.

Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow.

Ser Z, Gao X, Johnson C, Mehrmohamadi M, Liu X, Li S, Locasale JW.

Cell Rep. 2016 Jun 14;15(11):2367-76. doi: 10.1016/j.celrep.2016.05.035. Epub 2016 Jun 2.

4.

Adaptive response to l-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts.

Sayano T, Kawano Y, Kusada W, Arimoto Y, Esaki K, Hamano M, Udono M, Katakura Y, Ogawa T, Kato H, Hirabayashi Y, Furuya S.

FEBS Open Bio. 2016 Mar 3;6(4):303-16. doi: 10.1002/2211-5463.12038. eCollection 2016 Apr.

5.

Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.

Ducker GS, Chen L, Morscher RJ, Ghergurovich JM, Esposito M, Teng X, Kang Y, Rabinowitz JD.

Cell Metab. 2016 Jun 14;23(6):1140-53. doi: 10.1016/j.cmet.2016.04.016. Epub 2016 May 19.

PMID:
27211901
6.

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.

Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, Liu CM, Zhou M, Koh MJ, Chung H, Davidson SM, Luengo A, Wang AQ, Xu X, Yasgar A, Liu L, Rai G, Westover KD, Vander Heiden MG, Shen M, Gray NS, Boxer MB, Sabatini DM.

Nat Chem Biol. 2016 Jun;12(6):452-8. doi: 10.1038/nchembio.2070. Epub 2016 Apr 25.

PMID:
27110680
7.

Simultaneous tracing of carbon and nitrogen isotopes in human cells.

Nilsson R, Jain M.

Mol Biosyst. 2016 May 24;12(6):1929-37. doi: 10.1039/c6mb00009f.

PMID:
27098229
8.

KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment.

Zeitouni D, Pylayeva-Gupta Y, Der CJ, Bryant KL.

Cancers (Basel). 2016 Apr 18;8(4). pii: E45. doi: 10.3390/cancers8040045. Review.

9.

A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection.

Wang Q, Sun T, Cao Y, Gao P, Dong J, Fang Y, Fang Z, Sun X, Zhu Z.

Onco Targets Ther. 2016 Mar 11;9:1389-98. doi: 10.2147/OTT.S95862. eCollection 2016.

10.

Parkin Regulates the Activity of Pyruvate Kinase M2.

Liu K, Li F, Han H, Chen Y, Mao Z, Luo J, Zhao Y, Zheng B, Gu W, Zhao W.

J Biol Chem. 2016 May 6;291(19):10307-17. doi: 10.1074/jbc.M115.703066. Epub 2016 Mar 14.

11.

The specific role of plastidial glycolysis in photosynthetic and heterotrophic cells under scrutiny through the study of glyceraldehyde-3-phosphate dehydrogenase.

Anoman AD, Flores-Tornero M, Rosa-Telléz S, Muñoz-Bertomeu J, Segura J, Ros R.

Plant Signal Behav. 2016 Mar 3;11(3):e1128614. doi: 10.1080/15592324.2015.1128614.

PMID:
26953506
12.

Metabolic Heterogeneity in Human Lung Tumors.

Hensley CT, Faubert B, Yuan Q, Lev-Cohain N, Jin E, Kim J, Jiang L, Ko B, Skelton R, Loudat L, Wodzak M, Klimko C, McMillan E, Butt Y, Ni M, Oliver D, Torrealba J, Malloy CR, Kernstine K, Lenkinski RE, DeBerardinis RJ.

Cell. 2016 Feb 11;164(4):681-94. doi: 10.1016/j.cell.2015.12.034. Epub 2016 Feb 4.

PMID:
26853473
13.

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.

Mullarky E, Lucki NC, Beheshti Zavareh R, Anglin JL, Gomes AP, Nicolay BN, Wong JC, Christen S, Takahashi H, Singh PK, Blenis J, Warren JD, Fendt SM, Asara JM, DeNicola GM, Lyssiotis CA, Lairson LL, Cantley LC.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83. doi: 10.1073/pnas.1521548113. Epub 2016 Feb 1. Erratum in: Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1585.

PMID:
26831078
14.

Analysis of Host Gene Expression Profile in HIV-1 and HIV-2 Infected T-Cells.

Devadas K, Biswas S, Haleyurgirisetty M, Wood O, Ragupathy V, Lee S, Hewlett I.

PLoS One. 2016 Jan 28;11(1):e0147421. doi: 10.1371/journal.pone.0147421. eCollection 2016.

15.

Role of Increased n-acetylaspartate Levels in Cancer.

Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK.

J Natl Cancer Inst. 2016 Jan 26;108(6):djv426. doi: 10.1093/jnci/djv426.

PMID:
26819345
16.

Energy disruptors: rising stars in anticancer therapy?

Bost F, Decoux-Poullot AG, Tanti JF, Clavel S.

Oncogenesis. 2016 Jan 18;5:e188. doi: 10.1038/oncsis.2015.46. Review.

17.

ONE-CLASS DETECTION OF CELL STATES IN TUMOR SUBTYPES.

Sokolov A, Paull EO, Stuart JM.

Pac Symp Biocomput. 2016;21:405-16.

18.

KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism.

Zhao E, Ding J, Xia Y, Liu M, Ye B, Choi JH, Yan C, Dong Z, Huang S, Zha Y, Yang L, Cui H, Ding HF.

Cell Rep. 2016 Jan 26;14(3):506-19. doi: 10.1016/j.celrep.2015.12.053. Epub 2016 Jan 7.

19.

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.

Maddocks OD, Labuschagne CF, Adams PD, Vousden KH.

Mol Cell. 2016 Jan 21;61(2):210-21. doi: 10.1016/j.molcel.2015.12.014. Epub 2016 Jan 7.

20.

The Emerging Hallmarks of Cancer Metabolism.

Pavlova NN, Thompson CB.

Cell Metab. 2016 Jan 12;23(1):27-47. doi: 10.1016/j.cmet.2015.12.006. Review.

PMID:
26771115
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