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Items: 1 to 20 of 149


Targeting Transcription Factors in Cancer.

Bhagwat AS, Vakoc CR.

Trends Cancer. 2015 Sep 1;1(1):53-65.


Microgranular variant of acute promyelocytic leukemia with der(17) ins(17;15): A case report and review of the literature.

Guan H, Liu J, Guo X, Wu C, Yu H.

Exp Ther Med. 2015 Sep;10(3):1009-1012. Epub 2015 Jun 18.


Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells.

Wang L, Xiao H, Zhang X, Liao W, Fu S, Huang H.

Int J Oncol. 2015 Nov;47(5):1685-95. doi: 10.3892/ijo.2015.3163. Epub 2015 Sep 14.


Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation.

Wang QQ, Zhou XY, Zhang YF, Bu N, Zhou J, Cao FL, Naranmandura H.

Oncotarget. 2015 Sep 22;6(28):25646-59. doi: 10.18632/oncotarget.4662.


Tetraarsenictetrasulfide and Arsenic Trioxide Exert Synergistic Effects on Induction of Apoptosis and Differentiation in Acute Promyelocytic Leukemia Cells.

Wang S, Zhou M, Ouyang J, Geng Z, Wang Z.

PLoS One. 2015 Jun 25;10(6):e0130343. doi: 10.1371/journal.pone.0130343. eCollection 2015.


Development and validation of a 3-Plex RT-qPCR assay for the simultaneous detection and quantitation of the three PML-RARa fusion transcripts in acute promyelocytic leukemia.

Chen Z, Tong Y, Li Y, Gao Q, Wang Q, Fu C, Xia Z.

PLoS One. 2015 Mar 27;10(3):e0122530. doi: 10.1371/journal.pone.0122530. eCollection 2015.


Simple, rapid and accurate molecular diagnosis of acute promyelocytic leukemia by loop mediated amplification technology.

Spinelli O, Rambaldi A, Rigo F, Zanghì P, D'Agostini E, Amicarelli G, Colotta F, Divona M, Ciardi C, Coco FL, Minnucci G.

Oncoscience. 2014 Dec 27;2(1):50-8. eCollection 2015.


Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A.

Uchino Y, Iriyama N, Hatta Y, Takei M.

Cancer Cell Int. 2015 Mar 12;15:30. doi: 10.1186/s12935-015-0176-2. eCollection 2015.


Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles.

Nott TJ, Petsalaki E, Farber P, Jervis D, Fussner E, Plochowietz A, Craggs TD, Bazett-Jones DP, Pawson T, Forman-Kay JD, Baldwin AJ.

Mol Cell. 2015 Mar 5;57(5):936-47. doi: 10.1016/j.molcel.2015.01.013.


Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression.

Chen Y, Wright J, Meng X, Leppard KN.

Mol Cell Biol. 2015 May;35(10):1660-72. doi: 10.1128/MCB.01478-14. Epub 2015 Mar 2.


Dose-dependent effects of selenite (Se(4+)) on arsenite (As(3+))-induced apoptosis and differentiation in acute promyelocytic leukemia cells.

Wang S, Geng Z, Shi N, Li X, Wang Z.

Cell Death Dis. 2015 Jan 15;6:e1596. doi: 10.1038/cddis.2014.563.


PML nuclear bodies: assembly and oxidative stress-sensitive sumoylation.

Sahin U, de Thé H, Lallemand-Breitenbach V.

Nucleus. 2014;5(6):499-507. doi: 10.4161/19491034.2014.970104. Review.


Global characteristics of childhood acute promyelocytic leukemia.

Zhang L, Samad A, Pombo-de-Oliveira MS, Scelo G, Smith MT, Feusner J, Wiemels JL, Metayer C.

Blood Rev. 2015 Mar;29(2):101-25. doi: 10.1016/j.blre.2014.09.013. Epub 2014 Sep 30. Review.


Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia.

Werner B, Gallagher RE, Paietta EM, Litzow MR, Tallman MS, Wiernik PH, Slack JL, Willman CL, Sun Z, Traulsen A, Dingli D.

Cancer Res. 2014 Oct 1;74(19):5386-96. doi: 10.1158/0008-5472.CAN-14-1210. Epub 2014 Jul 31.


p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells.

Trocoli A, Bensadoun P, Richard E, Labrunie G, Merhi F, Schläfli AM, Brigger D, Souquere S, Pierron G, Pasquet JM, Soubeyran P, Reiffers J, Ségal-Bendirdjian E, Tschan MP, Djavaheri-Mergny M.

Cell Death Differ. 2014 Dec;21(12):1852-61. doi: 10.1038/cdd.2014.102. Epub 2014 Jul 18.


Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.

Luo F, Zhuang Y, Sides MD, Sanchez CG, Shan B, White ES, Lasky JA.

Respir Res. 2014 Apr 24;15:51. doi: 10.1186/1465-9921-15-51.


Retinoid receptor signaling and autophagy in acute promyelocytic leukemia.

Orfali N, McKenna SL, Cahill MR, Gudas LJ, Mongan NP.

Exp Cell Res. 2014 May 15;324(1):1-12. doi: 10.1016/j.yexcr.2014.03.018. Epub 2014 Mar 30. Review.


A Dialog on the First 20 Years of PML Research and the Next 20 Ahead.

Bernardi R, Pandolfi PP.

Front Oncol. 2014 Feb 10;4:23. doi: 10.3389/fonc.2014.00023. eCollection 2014. Review.


The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1.

Mathieu MG, Miles AK, Ahmad M, Buczek ME, Pockley AG, Rees RC, Regad T.

Cell Death Dis. 2014 Feb 13;5:e1061. doi: 10.1038/cddis.2014.29.


Topoisomerase II and leukemia.

Pendleton M, Lindsey RH Jr, Felix CA, Grimwade D, Osheroff N.

Ann N Y Acad Sci. 2014 Mar;1310:98-110. doi: 10.1111/nyas.12358. Epub 2014 Feb 3. Review.

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