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Items: 18


RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

Yudina Z, Roa A, Johnson R, Biris N, de Souza Aranha Vieira DA, Tsiperson V, Reszka N, Taylor AB, Hart PJ, Demeler B, Diaz-Griffero F, Ivanov DN.

Cell Rep. 2015 Aug 4;12(5):788-97. doi: 10.1016/j.celrep.2015.06.072. Epub 2015 Jul 23.


TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.

Fletcher AJ, Christensen DE, Nelson C, Tan CP, Schaller T, Lehner PJ, Sundquist WI, Towers GJ.

EMBO J. 2015 Aug 4;34(15):2078-95. doi: 10.15252/embj.201490361. Epub 2015 Jun 22.


Potent restriction of HIV-1 and SIVmac239 replication by African green monkey TRIM5α.

Coren LV, Trivett MT, Jain S, Ayala VI, Del Prete GQ, Ohlen C, Ott DE.

Retrovirology. 2015 Feb 7;12:11. doi: 10.1186/s12977-015-0137-9.


African green monkey TRIM5α restriction in simian immunodeficiency virus-specific rhesus macaque effector CD4 T cells enhances their survival and antiviral function.

Jain S, Trivett MT, Ayala VI, Ohlen C, Ott DE.

J Virol. 2015 Apr;89(8):4449-56. doi: 10.1128/JVI.03598-14. Epub 2015 Feb 4.


Contribution of glutamine residues in the helix 4-5 loop to capsid-capsid interactions in simian immunodeficiency virus of macaques.

Tipper C, Sodroski JG.

J Virol. 2014 Sep;88(18):10289-302. doi: 10.1128/JVI.01388-14. Epub 2014 Jul 2.


Stabilized human TRIM5α protects human T cells from HIV-1 infection.

Richardson MW, Guo L, Xin F, Yang X, Riley JL.

Mol Ther. 2014 Jun;22(6):1084-95. doi: 10.1038/mt.2014.52. Epub 2014 Mar 25.


Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction.

Yang Y, Brandariz-Nuñez A, Fricke T, Ivanov DN, Sarnak Z, Diaz-Griffero F.

Virology. 2014 Jan 5;448:217-28. doi: 10.1016/j.virol.2013.10.012. Epub 2013 Oct 31.


Pressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.

Granier C, Battivelli E, Lécuroux C, Venet A, Lambotte O, Schmitt-Boulanger M, Delaugerre C, Molina JM, Chakrabarti LA, Clavel F, Hance AJ.

J Virol. 2013 Sep;87(18):10368-80. doi: 10.1128/JVI.01313-13. Epub 2013 Jul 17.


Retrovirus restriction by TRIM5 proteins requires recognition of only a small fraction of viral capsid subunits.

Shi J, Friedman DB, Aiken C.

J Virol. 2013 Aug;87(16):9271-8. doi: 10.1128/JVI.00713-13. Epub 2013 Jun 19.


Virus-specific effects of TRIM5α(rh) RING domain functions on restriction of retroviruses.

Li X, Kim J, Song B, Finzi A, Pacheco B, Sodroski J.

J Virol. 2013 Jul;87(13):7234-45. doi: 10.1128/JVI.00620-13. Epub 2013 May 1.


Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α.

Battivelli E, Lecossier D, Clavel F, Hance AJ.

PLoS One. 2013;8(1):e52434. doi: 10.1371/journal.pone.0052434. Epub 2013 Jan 8.


Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.

Brandariz-Nuñez A, Roa A, Valle-Casuso JC, Biris N, Ivanov D, Diaz-Griffero F.

Virology. 2013 Jan 20;435(2):463-71. doi: 10.1016/j.virol.2012.09.042. Epub 2012 Oct 16.


TRIM38 negatively regulates TLR3-mediated IFN-β signaling by targeting TRIF for degradation.

Xue Q, Zhou Z, Lei X, Liu X, He B, Wang J, Hung T.

PLoS One. 2012;7(10):e46825. doi: 10.1371/journal.pone.0046825. Epub 2012 Oct 8.


Recruitment and dynamics of proteasome association with rhTRIM5α cytoplasmic complexes during HIV-1 infection.

Danielson CM, Cianci GC, Hope TJ.

Traffic. 2012 Sep;13(9):1206-17. doi: 10.1111/j.1600-0854.2012.01381.x. Epub 2012 Jun 19.


Role of Human TRIM5α in Intrinsic Immunity.

Nakayama EE, Shioda T.

Front Microbiol. 2012 Mar 15;3:97. doi: 10.3389/fmicb.2012.00097. eCollection 2012.


TRIM5α and Species Tropism of HIV/SIV.

Nakayama EE, Shioda T.

Front Microbiol. 2012 Jan 24;3:13. doi: 10.3389/fmicb.2012.00013. eCollection 2012.


RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating.

Roa A, Hayashi F, Yang Y, Lienlaf M, Zhou J, Shi J, Watanabe S, Kigawa T, Yokoyama S, Aiken C, Diaz-Griffero F.

J Virol. 2012 Feb;86(3):1717-27. doi: 10.1128/JVI.05811-11. Epub 2011 Nov 23.


Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity.

Battivelli E, Migraine J, Lecossier D, Yeni P, Clavel F, Hance AJ.

J Virol. 2011 Nov;85(22):11846-54. doi: 10.1128/JVI.05201-11. Epub 2011 Sep 14.

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