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A Molecular and Whole Body Insight of the Mechanisms Surrounding Glucose Disposal and Insulin Resistance with Hypoxic Treatment in Skeletal Muscle.

Mackenzie RW, Watt P.

J Diabetes Res. 2016;2016:6934937. doi: 10.1155/2016/6934937. Epub 2016 May 5. Review.


Hypoxia promotes drug resistance in osteosarcoma cells via activating AMP-activated protein kinase (AMPK) signaling.

Zhao C, Zhang Q, Yu T, Sun S, Wang W, Liu G.

J Bone Oncol. 2016 Jan 28;5(1):22-9. doi: 10.1016/j.jbo.2016.01.002. eCollection 2016 Mar.


Combined pharmacological activation of AMPK and PPAR╬┤ potentiates the effects of exercise in trained mice.

Manio MC, Inoue K, Fujitani M, Matsumura S, Fushiki T.

Physiol Rep. 2016 Mar;4(5). pii: e12625. doi: 10.14814/phy2.12625.



Arulkumaran N, Deutschman CS, Pinsky MR, Zuckerbraun B, Schumacker PT, Gomez H, Gomez A, Murray P, Kellum JA; ADQI XIV Workgroup.

Shock. 2016 Mar;45(3):271-81. doi: 10.1097/SHK.0000000000000463.


O2 sensing, mitochondria and ROS signaling: The fog is lifting.

Waypa GB, Smith KA, Schumacker PT.

Mol Aspects Med. 2016 Feb-Mar;47-48:76-89. doi: 10.1016/j.mam.2016.01.002. Epub 2016 Jan 14. Review.


Interplay between oxidant species and energy metabolism.

Quijano C, Trujillo M, Castro L, Trostchansky A.

Redox Biol. 2016 Aug;8:28-42. doi: 10.1016/j.redox.2015.11.010. Epub 2015 Nov 30.


Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4.

Suresh K, Servinsky L, Reyes J, Baksh S, Undem C, Caterina M, Pearse DB, Shimoda LA.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1467-77. doi: 10.1152/ajplung.00275.2015. Epub 2015 Oct 9.


Store-Operated Calcium Channels.

Prakriya M, Lewis RS.

Physiol Rev. 2015 Oct;95(4):1383-436. doi: 10.1152/physrev.00020.2014. Review.


Effect of metformin on Schwann cells under hypoxia condition.

Ma J, Liu J, Yu H, Chen Y, Wang Q, Xiang L.

Int J Clin Exp Pathol. 2015 Jun 1;8(6):6748-55. eCollection 2015.


The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism.

Allende-Vega N, Krzywinska E, Orecchioni S, Lopez-Royuela N, Reggiani F, Talarico G, Rossi JF, Rossignol R, Hicheri Y, Cartron G, Bertolini F, Villalba M.

Oncotarget. 2015 Aug 7;6(22):19228-45.


Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells.

Chen S, Sang N.

J Cell Biochem. 2016 Feb;117(2):267-78. doi: 10.1002/jcb.25283.


Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling.

Sinha RA, Singh BK, Zhou J, Wu Y, Farah BL, Ohba K, Lesmana R, Gooding J, Bay BH, Yen PM.

Autophagy. 2015;11(8):1341-57. doi: 10.1080/15548627.2015.1061849.


AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1╬▒ and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol.

Chen S, Yin C, Lao T, Liang D, He D, Wang C, Sang N.

Cell Cycle. 2015 Aug 3;14(15):2520-36. doi: 10.1080/15384101.2015.1055426. Epub 2015 Jun 10.


Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism.

Liemburg-Apers DC, Willems PH, Koopman WJ, Grefte S.

Arch Toxicol. 2015 Aug;89(8):1209-26. doi: 10.1007/s00204-015-1520-y. Epub 2015 Jun 6. Review.


Antioxidant Therapy: Is it your Gateway to Improved Cardiovascular Health?

Abid MR, Sellke FW.

Pharm Anal Acta. 2015 Jan;6(1). pii: 323.


A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice.

Rousset CI, Leiper FC, Kichev A, Gressens P, Carling D, Hagberg H, Thornton C.

J Neurochem. 2015 Apr;133(2):242-52. doi: 10.1111/jnc.13034. Epub 2015 Feb 24.


Hypoxia-dependent reactive oxygen species signaling in the pulmonary circulation: focus on ion channels.

Veit F, Pak O, Brandes RP, Weissmann N.

Antioxid Redox Signal. 2015 Feb 20;22(6):537-52. doi: 10.1089/ars.2014.6234. Review.


Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis.

Nijland PG, Witte ME, van het Hof B, van der Pol S, Bauer J, Lassmann H, van der Valk P, de Vries HE, van Horssen J.

Acta Neuropathol Commun. 2014 Dec 10;2:170. doi: 10.1186/s40478-014-0170-2.


Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation.

Groenendijk FH, Mellema WW, van der Burg E, Schut E, Hauptmann M, Horlings HM, Willems SM, van den Heuvel MM, Jonkers J, Smit EF, Bernards R.

Int J Cancer. 2015 Mar 15;136(6):1434-44. doi: 10.1002/ijc.29113. Epub 2014 Aug 8.


AMPK knockdown in placental trophoblast cells results in altered morphology and function.

Carey EA, Albers RE, Doliboa SR, Hughes M, Wyatt CN, Natale DR, Brown TL.

Stem Cells Dev. 2014 Dec 1;23(23):2921-30. doi: 10.1089/scd.2014.0092. Epub 2014 Aug 18.

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