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Results: 1 to 20 of 60

1.

Biophysical fitness landscapes for transcription factor binding sites.

Haldane A, Manhart M, Morozov AV.

PLoS Comput Biol. 2014 Jul 10;10(7):e1003683. doi: 10.1371/journal.pcbi.1003683. eCollection 2014 Jul.

PMID:
25010228
[PubMed - in process]
Free PMC Article
2.

Recombination accelerates adaptation on a large-scale empirical fitness landscape in HIV-1.

Moradigaravand D, Kouyos R, Hinkley T, Haddad M, Petropoulos CJ, Engelst├Ądter J, Bonhoeffer S.

PLoS Genet. 2014 Jun 26;10(6):e1004439. doi: 10.1371/journal.pgen.1004439. eCollection 2014 Jun.

PMID:
24967626
[PubMed - in process]
Free PMC Article
3.

Adaptation of a cyanobacterium to a biochemically rich environment in experimental evolution as an initial step toward a chloroplast-like state.

Hosoda K, Habuchi M, Suzuki S, Miyazaki M, Takikawa G, Sakurai T, Kashiwagi A, Sueyoshi M, Matsumoto Y, Kiuchi A, Mori K, Yomo T.

PLoS One. 2014 May 29;9(5):e98337. doi: 10.1371/journal.pone.0098337. eCollection 2014.

PMID:
24874568
[PubMed - in process]
Free PMC Article
4.

The changing geometry of a fitness landscape along an adaptive walk.

Greene D, Crona K.

PLoS Comput Biol. 2014 May 22;10(5):e1003520. doi: 10.1371/journal.pcbi.1003520. eCollection 2014 May.

PMID:
24853069
[PubMed - in process]
Free PMC Article
5.

Epistatically interacting substitutions are enriched during adaptive protein evolution.

Gong LI, Bloom JD.

PLoS Genet. 2014 May 8;10(5):e1004328. doi: 10.1371/journal.pgen.1004328. eCollection 2014 May.

PMID:
24811236
[PubMed - in process]
Free PMC Article
6.

Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations.

Chou HH, Delaney NF, Draghi JA, Marx CJ.

PLoS Genet. 2014 Feb 27;10(2):e1004149. doi: 10.1371/journal.pgen.1004149. eCollection 2014 Feb.

PMID:
24586190
[PubMed - in process]
Free PMC Article
7.

The origins of specialization: insights from bacteria held 25 years in captivity.

Cooper VS.

PLoS Biol. 2014 Feb 18;12(2):e1001790. doi: 10.1371/journal.pbio.1001790. eCollection 2014 Feb.

PMID:
24558348
[PubMed - in process]
Free PMC Article
8.

Metabolic erosion primarily through mutation accumulation, and not tradeoffs, drives limited evolution of substrate specificity in Escherichia coli.

Leiby N, Marx CJ.

PLoS Biol. 2014 Feb 18;12(2):e1001789. doi: 10.1371/journal.pbio.1001789. eCollection 2014 Feb.

PMID:
24558347
[PubMed - in process]
Free PMC Article
9.

Rates of fitness decline and rebound suggest pervasive epistasis.

Perfeito L, Sousa A, Bataillon T, Gordo I.

Evolution. 2014 Jan;68(1):150-62. doi: 10.1111/evo.12234. Epub 2013 Sep 2.

PMID:
24372601
[PubMed - in process]
Free PMC Article
10.

Conservative sex and the benefits of transformation in Streptococcus pneumoniae.

Engelmoer DJ, Donaldson I, Rozen DE.

PLoS Pathog. 2013;9(11):e1003758. doi: 10.1371/journal.ppat.1003758. Epub 2013 Nov 14.

PMID:
24244172
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Experimental evolution of an alternating uni- and multicellular life cycle in Chlamydomonas reinhardtii.

Ratcliff WC, Herron MD, Howell K, Pentz JT, Rosenzweig F, Travisano M.

Nat Commun. 2013;4:2742. doi: 10.1038/ncomms3742.

PMID:
24193369
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance.

Miller C, Kong J, Tran TT, Arias CA, Saxer G, Shamoo Y.

Antimicrob Agents Chemother. 2013 Nov;57(11):5373-83. doi: 10.1128/AAC.01473-13. Epub 2013 Aug 19. Erratum in: Antimicrob Agents Chemother. 2014 Jan;58(1):631.

PMID:
23959318
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The conditional nature of genetic interactions: the consequences of wild-type backgrounds on mutational interactions in a genome-wide modifier screen.

Chari S, Dworkin I.

PLoS Genet. 2013;9(8):e1003661. doi: 10.1371/journal.pgen.1003661. Epub 2013 Aug 1.

PMID:
23935530
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Experiments on the role of deleterious mutations as stepping stones in adaptive evolution.

Covert AW 3rd, Lenski RE, Wilke CO, Ofria C.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3171-8. doi: 10.1073/pnas.1313424110. Epub 2013 Aug 5.

PMID:
23918358
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The cost of antibiotic resistance depends on evolutionary history in Escherichia coli.

Angst DC, Hall AR.

BMC Evol Biol. 2013 Aug 2;13:163. doi: 10.1186/1471-2148-13-163.

PMID:
23914906
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The strength of genetic interactions scales weakly with mutational effects.

Velenich A, Gore J.

Genome Biol. 2013 Jul 26;14(7):R76. doi: 10.1186/gb-2013-14-7-r76.

PMID:
23889884
[PubMed - in process]
Free PMC Article
17.

Bacterial adaptation through loss of function.

Hottes AK, Freddolino PL, Khare A, Donnell ZN, Liu JC, Tavazoie S.

PLoS Genet. 2013;9(7):e1003617. doi: 10.1371/journal.pgen.1003617. Epub 2013 Jul 11.

PMID:
23874220
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Patterns of Epistasis between beneficial mutations in an antibiotic resistance gene.

Schenk MF, Szendro IG, Salverda ML, Krug J, de Visser JA.

Mol Biol Evol. 2013 Aug;30(8):1779-87. doi: 10.1093/molbev/mst096. Epub 2013 May 15.

PMID:
23676768
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Genotype to phenotype mapping and the fitness landscape of the E. coli lac promoter.

Otwinowski J, Nemenman I.

PLoS One. 2013 May 1;8(5):e61570. doi: 10.1371/journal.pone.0061570. Print 2013.

PMID:
23650500
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence".

Tarabichi M, Antoniou A, Saiselet M, Pita JM, Andry G, Dumont JE, Detours V, Maenhaut C.

Cancer Metastasis Rev. 2013 Dec;32(3-4):403-21. doi: 10.1007/s10555-013-9431-y.

PMID:
23615877
[PubMed - in process]
Free PMC Article

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