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Items: 18

1.

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.

Wetmore BA, Wambaugh JF, Allen B, Ferguson SS, Sochaski MA, Setzer RW, Houck KA, Strope CL, Cantwell K, Judson RS, LeCluyse E, Clewell HJ, Thomas RS, Andersen ME.

Toxicol Sci. 2015 Nov;148(1):121-36. doi: 10.1093/toxsci/kfv171. Epub 2015 Aug 6.

2.

Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.

Usta OB, McCarty WJ, Bale S, Hegde M, Jindal R, Bhushan A, Golberg I, Yarmush ML.

Technology (Singap World Sci). 2015 Mar;3(1):1-26.

3.

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Goodson WH 3rd, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami GN, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Lyerly HK, Krishnan H, Ab Hamid H, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondráček J, Raju J, Roman J, Wise JP Sr, Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart ME, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van Larebeke N, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson PA, Dent P, Heneberg P, Darbre P, Sing Leung P, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, Andrade-Vieira R, Sinha RK, Mehta R, Vento R, Di Fiore R, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd Hamid R, Langie SA, Eltom SE, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engström W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu Z.

Carcinogenesis. 2015 Jun;36 Suppl 1:S254-96. doi: 10.1093/carcin/bgv039. Review. Erratum in: Carcinogenesis. 2016 Mar;37(3):344.

4.

Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions.

Kravchenko J, Corsini E, Williams MA, Decker W, Manjili MH, Otsuki T, Singh N, Al-Mulla F, Al-Temaimi R, Amedei A, Colacci AM, Vaccari M, Mondello C, Scovassi AI, Raju J, Hamid RA, Memeo L, Forte S, Roy R, Woodrick J, Salem HK, Ryan EP, Brown DG, Bisson WH, Lowe L, Lyerly HK.

Carcinogenesis. 2015 Jun;36 Suppl 1:S111-27. doi: 10.1093/carcin/bgv033. Epub 2015 May 22. Review.

5.

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.

Bal-Price A, Crofton KM, Leist M, Allen S, Arand M, Buetler T, Delrue N, FitzGerald RE, Hartung T, Heinonen T, Hogberg H, Bennekou SH, Lichtensteiger W, Oggier D, Paparella M, Axelstad M, Piersma A, Rached E, Schilter B, Schmuck G, Stoppini L, Tongiorgi E, Tiramani M, Monnet-Tschudi F, Wilks MF, Ylikomi T, Fritsche E.

Arch Toxicol. 2015 Feb;89(2):269-87. doi: 10.1007/s00204-015-1464-2. Epub 2015 Jan 25.

6.

Big data in chemical toxicity research: the use of high-throughput screening assays to identify potential toxicants.

Zhu H, Zhang J, Kim MT, Boison A, Sedykh A, Moran K.

Chem Res Toxicol. 2014 Oct 20;27(10):1643-51. doi: 10.1021/tx500145h. Epub 2014 Sep 16. Review.

7.

A short-term in vivo screen using fetal testosterone production, a key event in the phthalate adverse outcome pathway, to predict disruption of sexual differentiation.

Furr JR, Lambright CS, Wilson VS, Foster PM, Gray LE Jr.

Toxicol Sci. 2014 Aug 1;140(2):403-24. doi: 10.1093/toxsci/kfu081. Epub 2014 May 5.

8.

In silico analysis of the conservation of human toxicity and endocrine disruption targets in aquatic species.

McRobb FM, Sahagún V, Kufareva I, Abagyan R.

Environ Sci Technol. 2014;48(3):1964-72. doi: 10.1021/es404568a. Epub 2014 Jan 15.

9.

QSAR modeling: where have you been? Where are you going to?

Cherkasov A, Muratov EN, Fourches D, Varnek A, Baskin II, Cronin M, Dearden J, Gramatica P, Martin YC, Todeschini R, Consonni V, Kuz'min VE, Cramer R, Benigni R, Yang C, Rathman J, Terfloth L, Gasteiger J, Richard A, Tropsha A.

J Med Chem. 2014 Jun 26;57(12):4977-5010. doi: 10.1021/jm4004285. Epub 2014 Jan 6.

10.

A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment.

Nel AE, Nasser E, Godwin H, Avery D, Bahadori T, Bergeson L, Beryt E, Bonner JC, Boverhof D, Carter J, Castranova V, Deshazo JR, Hussain SM, Kane AB, Klaessig F, Kuempel E, Lafranconi M, Landsiedel R, Malloy T, Miller MB, Morris J, Moss K, Oberdorster G, Pinkerton K, Pleus RC, Shatkin JA, Thomas R, Tolaymat T, Wang A, Wong J.

ACS Nano. 2013 Aug 27;7(8):6422-33. doi: 10.1021/nn4037927. Epub 2013 Aug 7.

11.

Advancing human health risk assessment: integrating recent advisory committee recommendations.

Dourson M, Becker RA, Haber LT, Pottenger LH, Bredfeldt T, Fenner-Crisp PA.

Crit Rev Toxicol. 2013 Jul;43(6):467-92. doi: 10.3109/10408444.2013.807223. Review.

12.

The Tox21 robotic platform for the assessment of environmental chemicals--from vision to reality.

Attene-Ramos MS, Miller N, Huang R, Michael S, Itkin M, Kavlock RJ, Austin CP, Shinn P, Simeonov A, Tice RR, Xia M.

Drug Discov Today. 2013 Aug;18(15-16):716-23. doi: 10.1016/j.drudis.2013.05.015. Epub 2013 May 31. Review.

13.

Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.

Sipes NS, Martin MT, Kothiya P, Reif DM, Judson RS, Richard AM, Houck KA, Dix DJ, Kavlock RJ, Knudsen TB.

Chem Res Toxicol. 2013 Jun 17;26(6):878-95. doi: 10.1021/tx400021f. Epub 2013 May 16.

14.

Improving the human hazard characterization of chemicals: a Tox21 update.

Tice RR, Austin CP, Kavlock RJ, Bucher JR.

Environ Health Perspect. 2013 Jul;121(7):756-65. doi: 10.1289/ehp.1205784. Epub 2013 Apr 19. Review.

15.

A computational model predicting disruption of blood vessel development.

Kleinstreuer N, Dix D, Rountree M, Baker N, Sipes N, Reif D, Spencer R, Knudsen T.

PLoS Comput Biol. 2013 Apr;9(4):e1002996. doi: 10.1371/journal.pcbi.1002996. Epub 2013 Apr 4.

16.

A three-stage algorithm to make toxicologically relevant activity calls from quantitative high throughput screening data.

Shockley KR.

Environ Health Perspect. 2012 Aug;120(8):1107-15. doi: 10.1289/ehp.1104688. Epub 2012 May 10.

17.

Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System.

Judson RS, Martin MT, Egeghy P, Gangwal S, Reif DM, Kothiya P, Wolf M, Cathey T, Transue T, Smith D, Vail J, Frame A, Mosher S, Cohen Hubal EA, Richard AM.

Int J Mol Sci. 2012;13(2):1805-31. doi: 10.3390/ijms13021805. Epub 2012 Feb 9. Review.

18.

Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data.

Rusyn I, Sedykh A, Low Y, Guyton KZ, Tropsha A.

Toxicol Sci. 2012 May;127(1):1-9. doi: 10.1093/toxsci/kfs095. Epub 2012 Mar 2.

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