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Results: 1 to 20 of 73

1.

New Approaches to Target T-ALL.

Roti G, Stegmaier K.

Front Oncol. 2014 Jul 8;4:170. doi: 10.3389/fonc.2014.00170. eCollection 2014. Review.

PMID:
25072021
[PubMed]
Free PMC Article
2.

The challenge of targeting notch in hematologic malignancies.

Hernandez Tejada FN, Galvez Silva JR, Zweidler-McKay PA.

Front Pediatr. 2014 Jun 10;2:54. doi: 10.3389/fped.2014.00054. eCollection 2014. Review.

PMID:
24959528
[PubMed]
Free PMC Article
3.

Proteinase-Activated Receptor 1 (PAR1) regulates leukemic stem cell functions.

Bäumer N, Krause A, Köhler G, Lettermann S, Evers G, Hascher A, Bäumer S, Berdel WE, Müller-Tidow C, Tickenbrock L.

PLoS One. 2014 Apr 16;9(4):e94993. doi: 10.1371/journal.pone.0094993. eCollection 2014.

PMID:
24740120
[PubMed - in process]
Free PMC Article
4.

Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.

Alaña L, Sesé M, Cánovas V, Punyal Y, Fernández Y, Abasolo I, de Torres I, Ruiz C, Espinosa L, Bigas A, Y Cajal SR, Fernández PL, Serras F, Corominas M, Thomson TM, Paciucci R.

Mol Cancer. 2014 Mar 31;13:74. doi: 10.1186/1476-4598-13-74.

PMID:
24684754
[PubMed - in process]
Free PMC Article
5.

Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia.

Belyea BC, Xu F, Pentz ES, Medrano S, Li M, Hu Y, Turner S, Legallo R, Jones CA, Tario JD, Liang P, Gross KW, Sequeira-Lopez ML, Gomez RA.

Nat Commun. 2014;5:3273. doi: 10.1038/ncomms4273.

PMID:
24549417
[PubMed - in process]
Free PMC Article
6.

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts.

Kode A, Manavalan JS, Mosialou I, Bhagat G, Rathinam CV, Luo N, Khiabanian H, Lee A, Murty VV, Friedman R, Brum A, Park D, Galili N, Mukherjee S, Teruya-Feldstein J, Raza A, Rabadan R, Berman E, Kousteni S.

Nature. 2014 Feb 13;506(7487):240-4. doi: 10.1038/nature12883. Epub 2014 Jan 15.

PMID:
24429522
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Animal models to study the mutational landscape for oral cavity and oropharyngeal cancers.

Spiotto MT, Pytynia M, Liu GF, Ranck MC, Widau R.

J Oral Maxillofac Res. 2013 Apr 1;4(1):e1. doi: 10.5037/jomr.2013.4101. Review.

PMID:
24422024
[PubMed]
Free PMC Article
8.

Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells.

Xiong H, Maraver A, Latkowski JA, Henderson T, Schlessinger K, Ding Y, Shen J, Tadokoro CE, Lafaille JJ.

PLoS One. 2013 Dec 27;8(12):e84841. doi: 10.1371/journal.pone.0084841. eCollection 2013.

PMID:
24386421
[PubMed - in process]
Free PMC Article
9.

Alternative lengthening of telomeres: recurrent cytogenetic aberrations and chromosome stability under extreme telomere dysfunction.

Sakellariou D, Chiourea M, Raftopoulou C, Gagos S.

Neoplasia. 2013 Nov;15(11):1301-13.

PMID:
24339742
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Disparity expression of Notch1 in benign and malignant colorectal diseases.

Huang R, Tang Q, You Q, Liu Z, Wang G, Chen Y, Sun Y, Muhammad S, Wang X.

PLoS One. 2013 Dec 3;8(12):e81005. doi: 10.1371/journal.pone.0081005. eCollection 2013.

PMID:
24312514
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Pituitary gland development and disease: from stem cell to hormone production.

Davis SW, Ellsworth BS, Peréz Millan MI, Gergics P, Schade V, Foyouzi N, Brinkmeier ML, Mortensen AH, Camper SA.

Curr Top Dev Biol. 2013;106:1-47. doi: 10.1016/B978-0-12-416021-7.00001-8. Review.

PMID:
24290346
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.

Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL.

J Exp Med. 2013 Nov 18;210(12):2641-59. doi: 10.1084/jem.20131141. Epub 2013 Nov 11.

PMID:
24218140
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.

De Obaldia ME, Bell JJ, Wang X, Harly C, Yashiro-Ohtani Y, DeLong JH, Zlotoff DA, Sultana DA, Pear WS, Bhandoola A.

Nat Immunol. 2013 Dec;14(12):1277-84. doi: 10.1038/ni.2760. Epub 2013 Nov 3.

PMID:
24185616
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.

Phelan JD, Saba I, Zeng H, Kosan C, Messer MS, Olsson HA, Fraszczak J, Hildeman DA, Aronow BJ, Möröy T, Grimes HL.

PLoS Genet. 2013;9(9):e1003713. doi: 10.1371/journal.pgen.1003713. Epub 2013 Sep 12.

PMID:
24068942
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells.

Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link KA, Mizukawa B, Grimes HL, Kurokawa M, Liu PP, Huang G, Mulloy JC.

J Clin Invest. 2013 Sep 3;123(9):3876-88. doi: 10.1172/JCI68557. Epub 2013 Aug 27. Erratum in: J Clin Invest. 2013 Nov 1;123(11):4979.

PMID:
23979164
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Oral cavity and oropharyngeal squamous cell carcinoma genomics.

Tan M, Myers JN, Agrawal N.

Otolaryngol Clin North Am. 2013 Aug;46(4):545-66. doi: 10.1016/j.otc.2013.04.001. Epub 2013 Jun 17. Review.

PMID:
23910469
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Gamma secretase inhibitors of Notch signaling.

Olsauskas-Kuprys R, Zlobin A, Osipo C.

Onco Targets Ther. 2013 Jul 23;6:943-55. doi: 10.2147/OTT.S33766. Print 2013.

PMID:
23901284
[PubMed]
Free PMC Article
18.

Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.

Sandy AR, Stoolman J, Malott K, Pongtornpipat P, Segal BM, Maillard I.

J Immunol. 2013 Aug 15;191(4):1606-13. doi: 10.4049/jimmunol.1301116. Epub 2013 Jul 3.

PMID:
23825310
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors.

Dailey DD, Anfinsen KP, Pfaff LE, Ehrhart EJ, Charles JB, Bønsdorff TB, Thamm DH, Powers BE, Jonasdottir TJ, Duval DL.

BMC Vet Res. 2013 Jul 1;9:130. doi: 10.1186/1746-6148-9-130.

PMID:
23816051
[PubMed - in process]
Free PMC Article
20.

miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.

Chen P, Price C, Li Z, Li Y, Cao D, Wiley A, He C, Gurbuxani S, Kunjamma RB, Huang H, Jiang X, Arnovitz S, Xu M, Hong GM, Elkahloun AG, Neilly MB, Wunderlich M, Larson RA, Le Beau MM, Mulloy JC, Liu PP, Rowley JD, Chen J.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11511-6. doi: 10.1073/pnas.1310144110. Epub 2013 Jun 24.

PMID:
23798388
[PubMed - indexed for MEDLINE]
Free PMC Article

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