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Items: 11


Emerging Vaccine Technologies.

Loomis RJ, Johnson PR.

Vaccines (Basel). 2015 May 26;3(2):429-47. doi: 10.3390/vaccines3020429. Review.


Computational design and experimental verification of a symmetric protein homodimer.

Mou Y, Huang PS, Hsu FC, Huang SJ, Mayo SL.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10714-9. doi: 10.1073/pnas.1505072112. Epub 2015 Aug 12.


Strategies to control the binding mode of de novo designed protein interactions.

Der BS, Kuhlman B.

Curr Opin Struct Biol. 2013 Aug;23(4):639-46. doi: 10.1016/ Epub 2013 May 31. Review.


Combined computational design of a zinc-binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin binding.

Der BS, Jha RK, Lewis SM, Thompson PM, Guntas G, Kuhlman B.

Proteins. 2013 Jul;81(7):1245-55. doi: 10.1002/prot.24280. Epub 2013 Apr 20. Erratum in: Proteins. 2013 Sep;81(9):1678. Jha, Raamesh K [corrected to Jha, Ramesh K].


Structure-based redesign of proteins for minimal T-cell epitope content.

Choi Y, Griswold KE, Bailey-Kellogg C.

J Comput Chem. 2013 Apr 5;34(10):879-91. doi: 10.1002/jcc.23213. Epub 2013 Jan 8.


A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds.

Stranges PB, Kuhlman B.

Protein Sci. 2013 Jan;22(1):74-82. doi: 10.1002/pro.2187. Epub 2012 Nov 29.


Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi.

Jia M, Li J, Zhu J, Wen W, Zhang M, Wang W.

J Biol Chem. 2012 Oct 26;287(44):36766-76. doi: 10.1074/jbc.M112.391607. Epub 2012 Sep 5.


Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core.

Murphy GS, Mills JL, Miley MJ, Machius M, Szyperski T, Kuhlman B.

Structure. 2012 Jun 6;20(6):1086-96. doi: 10.1016/j.str.2012.03.026. Epub 2012 May 24.


Computational design of a symmetric homodimer using β-strand assembly.

Stranges PB, Machius M, Miley MJ, Tripathy A, Kuhlman B.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20562-7. doi: 10.1073/pnas.1115124108. Epub 2011 Dec 5.


Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.

Der BS, Machius M, Miley MJ, Mills JL, Szyperski T, Kuhlman B.

J Am Chem Soc. 2012 Jan 11;134(1):375-85. doi: 10.1021/ja208015j. Epub 2011 Dec 15.


RosettaRemodel: a generalized framework for flexible backbone protein design.

Huang PS, Ban YE, Richter F, Andre I, Vernon R, Schief WR, Baker D.

PLoS One. 2011;6(8):e24109. doi: 10.1371/journal.pone.0024109. Epub 2011 Aug 31.

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