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Results: 9

1.

Strategies to control the binding mode of de novo designed protein interactions.

Der BS, Kuhlman B.

Curr Opin Struct Biol. 2013 Aug;23(4):639-46. doi: 10.1016/j.sbi.2013.04.010. Epub 2013 May 31. Review.

PMID:
23731800
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Combined computational design of a zinc-binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin binding.

Der BS, Jha RK, Lewis SM, Thompson PM, Guntas G, Kuhlman B.

Proteins. 2013 Jul;81(7):1245-55. doi: 10.1002/prot.24280. Epub 2013 Apr 20. Erratum in: Proteins. 2013 Sep;81(9):1678. Jha, Raamesh K [corrected to Jha, Ramesh K].

PMID:
23504819
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Structure-based redesign of proteins for minimal T-cell epitope content.

Choi Y, Griswold KE, Bailey-Kellogg C.

J Comput Chem. 2013 Apr 5;34(10):879-91. doi: 10.1002/jcc.23213. Epub 2013 Jan 8.

PMID:
23299435
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds.

Stranges PB, Kuhlman B.

Protein Sci. 2013 Jan;22(1):74-82. doi: 10.1002/pro.2187. Epub 2012 Nov 29.

PMID:
23139141
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi.

Jia M, Li J, Zhu J, Wen W, Zhang M, Wang W.

J Biol Chem. 2012 Oct 26;287(44):36766-76. doi: 10.1074/jbc.M112.391607. Epub 2012 Sep 5.

PMID:
22952234
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core.

Murphy GS, Mills JL, Miley MJ, Machius M, Szyperski T, Kuhlman B.

Structure. 2012 Jun 6;20(6):1086-96. doi: 10.1016/j.str.2012.03.026. Epub 2012 May 24.

PMID:
22632833
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Computational design of a symmetric homodimer using β-strand assembly.

Stranges PB, Machius M, Miley MJ, Tripathy A, Kuhlman B.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20562-7. doi: 10.1073/pnas.1115124108. Epub 2011 Dec 5.

PMID:
22143762
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.

Der BS, Machius M, Miley MJ, Mills JL, Szyperski T, Kuhlman B.

J Am Chem Soc. 2012 Jan 11;134(1):375-85. doi: 10.1021/ja208015j. Epub 2011 Dec 15.

PMID:
22092237
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

RosettaRemodel: a generalized framework for flexible backbone protein design.

Huang PS, Ban YE, Richter F, Andre I, Vernon R, Schief WR, Baker D.

PLoS One. 2011;6(8):e24109. doi: 10.1371/journal.pone.0024109. Epub 2011 Aug 31.

PMID:
21909381
[PubMed - indexed for MEDLINE]
Free PMC Article
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