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Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.

Mohammed MK, Shao C, Wang J, Wei Q, Wang X, Collier Z, Tang S, Liu H, Zhang F, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Shi LL, Athiviraham A, He TC, Lee MJ.

Genes Dis. 2016 Mar;3(1):11-40. Epub 2016 Jan 14.


Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6.

Schumacher CA, Joiner DM, Less KD, Drewry MO, Williams BO.

Bone Res. 2016 Mar 1;4:15042. doi: 10.1038/boneres.2015.42. eCollection 2016.


Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development.

Maruyama EO, Lin H, Chiu SY, Yu HM, Porter GA, Hsu W.

Sci Rep. 2016 Feb 17;6:20999. doi: 10.1038/srep20999.


Ectodermal Wnt controls nasal pit morphogenesis through modulation of the BMP/FGF/JNK signaling axis.

Zhu XJ, Liu Y, Yuan X, Wang M, Zhao W, Yang X, Zhang X, Hsu W, Qiu M, Zhang Z, Zhang Z.

Dev Dyn. 2016 Mar;245(3):414-26. doi: 10.1002/dvdy.24376. Epub 2016 Jan 8.


Differential variability and correlation of gene expression identifies key genes involved in neuronal differentiation.

Ando T, Kato R, Honda H.

BMC Syst Biol. 2015 Nov 19;9:82. doi: 10.1186/s12918-015-0231-6.


Molecular basis of cleft palates in mice.

Funato N, Nakamura M, Yanagisawa H.

World J Biol Chem. 2015 Aug 26;6(3):121-38. doi: 10.4331/wjbc.v6.i3.121. Review.


A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.

Maupin KA, Droscha CJ, Williams BO.

Bone Res. 2013 Mar 29;1(1):27-71. doi: 10.4248/BR201301004. eCollection 2013 Mar. Review.


Genome-Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR-140-5p.

Barter MJ, Tselepi M, Gómez R, Woods S, Hui W, Smith GR, Shanley DP, Clark IM, Young DA.

Stem Cells. 2015 Nov;33(11):3266-80. doi: 10.1002/stem.2093. Epub 2015 Jul 29.


Distinct requirements for Wntless in habenular development.

Kuan YS, Roberson S, Akitake CM, Fortuno L, Gamse J, Moens C, Halpern ME.

Dev Biol. 2015 Oct 15;406(2):117-28. doi: 10.1016/j.ydbio.2015.06.006. Epub 2015 Jun 23.


Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.

Das S, Yu S, Sakamori R, Vedula P, Feng Q, Flores J, Hoffman A, Fu J, Stypulkowski E, Rodriguez A, Dobrowolski R, Harada A, Hsu W, Bonder EM, Verzi MP, Gao N.

Development. 2015 Jun 15;142(12):2147-62. doi: 10.1242/dev.121046. Epub 2015 May 26.


Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation.

Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L.

BMC Biol. 2015 Apr 11;13:24. doi: 10.1186/s12915-015-0134-4.


Roles of GasderminA3 in Catagen-Telogen Transition During Hair Cycling.

Bai X, Lei M, Shi J, Yu Y, Qiu W, Lai X, Liu Y, Yang T, Yang L, Widelitz RB, Chuong CM, Lian X.

J Invest Dermatol. 2015 Sep;135(9):2162-72. doi: 10.1038/jid.2015.147. Epub 2015 Apr 10.


Wntless regulates dentin apposition and root elongation in the mandibular molar.

Bae CH, Kim TH, Ko SO, Lee JC, Yang X, Cho ES.

J Dent Res. 2015 Mar;94(3):439-45. doi: 10.1177/0022034514567198. Epub 2015 Jan 16.


Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.

Bankhead EJ, Colasanto MP, Dyorich KM, Jamrich M, Murtaugh LC, Fuhrmann S.

Am J Pathol. 2015 Jan;185(1):197-213. doi: 10.1016/j.ajpath.2014.09.002. Epub 2014 Nov 3.


Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation.

Tan SH, Senarath-Yapa K, Chung MT, Longaker MT, Wu JY, Nusse R.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5262-71. doi: 10.1073/pnas.1420463111. Epub 2014 Nov 24.


BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin.

Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z.

PLoS Genet. 2014 Oct 16;10(10):e1004687. doi: 10.1371/journal.pgen.1004687. eCollection 2014 Oct.


Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration.

Fu J, Yu HM, Chiu SY, Mirando AJ, Maruyama EO, Cheng JG, Hsu W.

PLoS Genet. 2014 Oct 9;10(10):e1004579. doi: 10.1371/journal.pgen.1004579. eCollection 2014 Oct.


High-throughput transcriptome sequencing identifies candidate genetic modifiers of vulnerability to fetal alcohol spectrum disorders.

Garic A, Berres ME, Smith SM.

Alcohol Clin Exp Res. 2014 Jul;38(7):1874-82. doi: 10.1111/acer.12457. Epub 2014 Jun 24.


Concentration-dependent effects of WNTLESS on WNT1/3A signaling.

Galli LM, Szabo LA, Li L, Htaik YM, Onguka O, Burrus LW.

Dev Dyn. 2014 Sep;243(9):1095-105. doi: 10.1002/dvdy.24149. Epub 2014 Jun 25.


Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.

Goodnough LH, Dinuoscio GJ, Ferguson JW, Williams T, Lang RA, Atit RP.

PLoS Genet. 2014 Feb 20;10(2):e1004152. doi: 10.1371/journal.pgen.1004152. eCollection 2014 Feb.

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