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Items: 1 to 20 of 27


Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins.

Calejo AI, Taskén K.

Front Pharmacol. 2015 Sep 8;6:192. doi: 10.3389/fphar.2015.00192. eCollection 2015. Review.


Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder.

Nygren PJ, Scott JD.

Front Pharmacol. 2015 Jul 28;6:158. doi: 10.3389/fphar.2015.00158. eCollection 2015. Review.


Compartmentalization role of A-kinase anchoring proteins (AKAPs) in mediating protein kinase A (PKA) signaling and cardiomyocyte hypertrophy.

Rababa'h A, Singh S, Suryavanshi SV, Altarabsheh SE, Deo SV, McConnell BK.

Int J Mol Sci. 2014 Dec 24;16(1):218-29. doi: 10.3390/ijms16010218. Review.


Anchored protein kinase A signalling in cardiac cellular electrophysiology.

Soni S, Scholten A, Vos MA, van Veen TA.

J Cell Mol Med. 2014 Nov;18(11):2135-46. doi: 10.1111/jcmm.12365. Epub 2014 Sep 12. Review.


A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases.

Poppinga WJ, Muñoz-Llancao P, González-Billault C, Schmidt M.

Br J Pharmacol. 2014 Dec;171(24):5603-23. doi: 10.1111/bph.12882. Review.


cAMP signaling in subcellular compartments.

Lefkimmiatis K, Zaccolo M.

Pharmacol Ther. 2014 Sep;143(3):295-304. doi: 10.1016/j.pharmthera.2014.03.008. Epub 2014 Apr 1. Review.


Advances in targeting cyclic nucleotide phosphodiesterases.

Maurice DH, Ke H, Ahmad F, Wang Y, Chung J, Manganiello VC.

Nat Rev Drug Discov. 2014 Apr;13(4):290-314. doi: 10.1038/nrd4228. Review.


Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.

Oldenburger A, Maarsingh H, Schmidt M.

Pharmaceuticals (Basel). 2012 Nov 30;5(12):1291-331. doi: 10.3390/ph5121291.


AKAP signaling complexes: pointing towards the next generation of therapeutic targets?

Esseltine JL, Scott JD.

Trends Pharmacol Sci. 2013 Dec;34(12):648-55. doi: 10.1016/ Epub 2013 Nov 12. Review.


Local cAMP signaling in disease at a glance.

Gold MG, Gonen T, Scott JD.

J Cell Sci. 2013 Oct 15;126(Pt 20):4537-43. doi: 10.1242/jcs.133751. Review.


Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions.

Schäfer G, Milić J, Eldahshan A, Götz F, Zühlke K, Schillinger C, Kreuchwig A, Elkins JM, Abdul Azeez KR, Oder A, Moutty MC, Masada N, Beerbaum M, Schlegel B, Niquet S, Schmieder P, Krause G, von Kries JP, Cooper DM, Knapp S, Rademann J, Rosenthal W, Klussmann E.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12187-91. doi: 10.1002/anie.201304686. Epub 2013 Sep 23. No abstract available.


Protein kinase A and phosphodiesterase-4D3 binding to coding polymorphisms of cardiac muscle anchoring protein (mAKAP).

Rababa'h A, Craft JW Jr, Wijaya CS, Atrooz F, Fan Q, Singh S, Guillory AN, Katsonis P, Lichtarge O, McConnell BK.

J Mol Biol. 2013 Sep 23;425(18):3277-88. doi: 10.1016/j.jmb.2013.06.014. Epub 2013 Jun 25.


Engineering A-kinase anchoring protein (AKAP)-selective regulatory subunits of protein kinase A (PKA) through structure-based phage selection.

Gold MG, Fowler DM, Means CK, Pawson CT, Stephany JJ, Langeberg LK, Fields S, Scott JD.

J Biol Chem. 2013 Jun 14;288(24):17111-21. doi: 10.1074/jbc.M112.447326. Epub 2013 Apr 26.


Small-molecule screening identifies modulators of aquaporin-2 trafficking.

Bogum J, Faust D, Zühlke K, Eichhorst J, Moutty MC, Furkert J, Eldahshan A, Neuenschwander M, von Kries JP, Wiesner B, Trimpert C, Deen PM, Valenti G, Rosenthal W, Klussmann E.

J Am Soc Nephrol. 2013 Apr;24(5):744-58. doi: 10.1681/ASN.2012030295. Epub 2013 Apr 4.


Refinement and discovery of new hotspots of copy-number variation associated with autism spectrum disorder.

Girirajan S, Dennis MY, Baker C, Malig M, Coe BP, Campbell CD, Mark K, Vu TH, Alkan C, Cheng Z, Biesecker LG, Bernier R, Eichler EE.

Am J Hum Genet. 2013 Feb 7;92(2):221-37. doi: 10.1016/j.ajhg.2012.12.016. Epub 2013 Jan 31.


Creating order from chaos: cellular regulation by kinase anchoring.

Scott JD, Dessauer CW, Taskén K.

Annu Rev Pharmacol Toxicol. 2013;53:187-210. doi: 10.1146/annurev-pharmtox-011112-140204. Epub 2012 Oct 8. Review.


Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation.

Jones BW, Brunet S, Gilbert ML, Nichols CB, Su T, Westenbroek RE, Scott JD, Catterall WA, McKnight GS.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17099-104. doi: 10.1073/pnas.1215219109. Epub 2012 Oct 3.


Anchoring proteins as regulators of signaling pathways.

Perino A, Ghigo A, Scott JD, Hirsch E.

Circ Res. 2012 Aug 3;111(4):482-92. doi: 10.1161/CIRCRESAHA.111.262899. Review.


Molecular evolution of A-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization.

Johnson KR, Nicodemus-Johnson J, Carnegie GK, Danziger RS.

BMC Evol Biol. 2012 Jul 26;12:125. doi: 10.1186/1471-2148-12-125.

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