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Results: 17

1.

The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.

Tourette C, Farina F, Vazquez-Manrique RP, Orfila AM, Voisin J, Hernandez S, Offner N, Parker JA, Menet S, Kim J, Lyu J, Choi SH, Cormier K, Edgerly CK, Bordiuk OL, Smith K, Louise A, Halford M, Stacker S, Vert JP, Ferrante RJ, Lu W, Neri C.

PLoS Biol. 2014 Jun 24;12(6):e1001895. doi: 10.1371/journal.pbio.1001895. eCollection 2014 Jun.

PMID:
24960609
[PubMed - in process]
Free PMC Article
2.

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.

Rotblat B, Southwell AL, Ehrnhoefer DE, Skotte NH, Metzler M, Franciosi S, Leprivier G, Somasekharan SP, Barokas A, Deng Y, Tang T, Mathers J, Cetinbas N, Daugaard M, Kwok B, Li L, Carnie CJ, Fink D, Nitsch R, Galpin JD, Ahern CA, Melino G, Penninger JM, Hayden MR, Sorensen PH.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3032-7. doi: 10.1073/pnas.1314421111. Epub 2014 Feb 10.

PMID:
24516159
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Maintenance of basal levels of autophagy in huntington's disease mouse models displaying metabolic dysfunction.

Baldo B, Soylu R, Petersén A.

PLoS One. 2013 Dec 20;8(12):e83050. doi: 10.1371/journal.pone.0083050. eCollection 2013.

PMID:
24376631
[PubMed - in process]
Free PMC Article
4.

Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice.

Young D, Mayer F, Vidotto N, Schweizer T, Berth R, Abramowski D, Shimshek DR, van der Putten PH, Schmid P.

PLoS One. 2013 Sep 23;8(9):e75108. doi: 10.1371/journal.pone.0075108. eCollection 2013.

PMID:
24086450
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence.

Parmentier F, Lejeune FX, Neri C.

Front Aging Neurosci. 2013 Jun 13;5:22. doi: 10.3389/fnagi.2013.00022. eCollection 2013.

PMID:
23781200
[PubMed]
Free PMC Article
6.

A novel cognitive-neurophysiological state biomarker in premanifest Huntington's disease validated on longitudinal data.

Beste C, Stock AK, Ness V, Hoffmann R, Lukas C, Saft C.

Sci Rep. 2013;3:1797. doi: 10.1038/srep01797.

PMID:
23652721
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo.

Ramos AD, Diaz A, Nellore A, Delgado RN, Park KY, Gonzales-Roybal G, Oldham MC, Song JS, Lim DA.

Cell Stem Cell. 2013 May 2;12(5):616-28. doi: 10.1016/j.stem.2013.03.003. Epub 2013 Apr 11.

PMID:
23583100
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Role of cerebral cortex in the neuropathology of Huntington's disease.

Estrada-Sánchez AM, Rebec GV.

Front Neural Circuits. 2013 Feb 18;7:19. doi: 10.3389/fncir.2013.00019. eCollection 2013. Review.

PMID:
23423362
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mouse models of polyglutamine diseases: review and data table. Part I.

Figiel M, Szlachcic WJ, Switonski PM, Gabka A, Krzyzosiak WJ.

Mol Neurobiol. 2012 Oct;46(2):393-429. doi: 10.1007/s12035-012-8315-4. Epub 2012 Sep 7. Review.

PMID:
22956270
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element.

Keilani S, Chandwani S, Dolios G, Bogush A, Beck H, Hatzopoulos AK, Rao GN, Thomas EA, Wang R, Ehrlich ME.

J Neurosci. 2012 May 16;32(20):6808-18. doi: 10.1523/JNEUROSCI.5448-11.2012.

PMID:
22593050
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.

Tang B, Becanovic K, Desplats PA, Spencer B, Hill AM, Connolly C, Masliah E, Leavitt BR, Thomas EA.

Hum Mol Genet. 2012 Jul 15;21(14):3097-111. doi: 10.1093/hmg/dds132. Epub 2012 Apr 6.

PMID:
22492998
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Huntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of disease.

Ehrlich ME.

Neurotherapeutics. 2012 Apr;9(2):270-84. doi: 10.1007/s13311-012-0112-2. Review.

PMID:
22441874
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease.

Lerner RP, Trejo Martinez Ldel C, Zhu C, Chesselet MF, Hickey MA.

Brain Res Bull. 2012 Apr 10;87(6):571-8. doi: 10.1016/j.brainresbull.2012.01.012. Epub 2012 Feb 4.

PMID:
22326483
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

Huntington's Disease and Striatal Signaling.

Roze E, Cahill E, Martin E, Bonnet C, Vanhoutte P, Betuing S, Caboche J.

Front Neuroanat. 2011 Aug 23;5:55. doi: 10.3389/fnana.2011.00055. eCollection 2011.

PMID:
22007160
[PubMed]
Free PMC Article
16.

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.

Raymond LA, André VM, Cepeda C, Gladding CM, Milnerwood AJ, Levine MS.

Neuroscience. 2011 Dec 15;198:252-73. doi: 10.1016/j.neuroscience.2011.08.052. Epub 2011 Aug 27. Review.

PMID:
21907762
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function.

Kim SH, Thomas CA, André VM, Cummings DM, Cepeda C, Levine MS, Ehrlich ME.

ASN Neuro. 2011 Jun 7;3(3):e00060. doi: 10.1042/AN20110009.

PMID:
21542802
[PubMed - indexed for MEDLINE]
Free PMC Article

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