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Items: 1 to 20 of 180


Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression.

Goldstein JD, Burlion A, Zaragoza B, Sendeyo K, Polansky JK, Huehn J, Piaggio E, Salomon BL, Marodon G.

PLoS One. 2016 Apr 14;11(4):e0153682. doi: 10.1371/journal.pone.0153682. eCollection 2016.


Signaling in T cells - is anything the m(a)TOR with the picture(s)?

Boothby M.

F1000Res. 2016 Feb 18;5. pii: F1000 Faculty Rev-191. doi: 10.12688/f1000research.7027.1. eCollection 2016. Review.


(Compl)Ex-Th17-Treg cell inter-relationship.

Obermajer N, Dahlke MH.

Oncoimmunology. 2015 Apr 27;5(1):e1040217. eCollection 2016.


T-bet Regulates Natural Regulatory T Cell Afferent Lymphatic Migration and Suppressive Function.

Xiong Y, Ahmad S, Iwami D, Brinkman CC, Bromberg JS.

J Immunol. 2016 Mar 15;196(6):2526-40. doi: 10.4049/jimmunol.1502537. Epub 2016 Feb 15.


Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity.

Haque M, Song J, Fino K, Sandhu P, Song X, Lei F, Zheng S, Ni B, Fang D, Song J.

Sci Rep. 2016 Feb 5;6:20588. doi: 10.1038/srep20588.


Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.

Bothur E, Raifer H, Haftmann C, Stittrich AB, Brüstle A, Brenner D, Bollig N, Bieringer M, Kang CH, Reinhard K, Camara B, Huber M, Visekruna A, Steinhoff U, Repenning A, Bauer UM, Sexl V, Radbruch A, Sparwasser T, Mashreghi MF, Wah Mak T, Lohoff M.

Nat Commun. 2015 Oct 13;6:8576. doi: 10.1038/ncomms9576.


Disrupted regulatory T cell homeostasis in inflammatory bowel diseases.

Pedros C, Duguet F, Saoudi A, Chabod M.

World J Gastroenterol. 2016 Jan 21;22(3):974-95. doi: 10.3748/wjg.v22.i3.974. Review.


Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis.

Wei J, Long L, Yang K, Guy C, Shrestha S, Chen Z, Wu C, Vogel P, Neale G, Green DR, Chi H.

Nat Immunol. 2016 Mar;17(3):277-85. doi: 10.1038/ni.3365. Epub 2016 Jan 25.


Treg stability: to be or not to be.

Overacre AE, Vignali DA.

Curr Opin Immunol. 2016 Apr;39:39-43. doi: 10.1016/j.coi.2015.12.009. Epub 2016 Jan 15. Review.


Unstable FoxP3+ T regulatory cells in NZW mice.

Dépis F, Kwon HK, Mathis D, Benoist C.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1345-50. doi: 10.1073/pnas.1524660113. Epub 2016 Jan 14.


Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection.

Wiesner DL, Smith KD, Kotov DI, Nielsen JN, Bohjanen PR, Nielsen K.

J Immunol. 2016 Jan 1;196(1):365-74. doi: 10.4049/jimmunol.1501871. Epub 2015 Nov 20.


Enhanced renewal of regulatory T cells in relation to CD4(+) conventional T lymphocytes in the peripheral compartment.

Nogueira Jde S, Canto FB, Nunes CF, Vianna PH, Paiva Lde S, Nóbrega A, Bellio M, Fucs R.

Immunology. 2016 Feb;147(2):221-39. doi: 10.1111/imm.12555. Epub 2015 Dec 17.


Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression.

Bending D, Giannakopoulou E, Lom H, Wedderburn LR.

J Immunol. 2015 Dec 15;195(12):5616-24. doi: 10.4049/jimmunol.1500391. Epub 2015 Nov 11.


Stable inhibitory activity of regulatory T cells requires the transcription factor Helios.

Kim HJ, Barnitz RA, Kreslavsky T, Brown FD, Moffett H, Lemieux ME, Kaygusuz Y, Meissner T, Holderried TA, Chan S, Kastner P, Haining WN, Cantor H.

Science. 2015 Oct 16;350(6258):334-9. doi: 10.1126/science.aad0616.


IL-7R signaling in regulatory T cells maintains peripheral and allograft tolerance in mice.

Schmaler M, Broggi MA, Lagarde N, Stöcklin BF, King CG, Finke D, Rossi SW.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13330-5. doi: 10.1073/pnas.1510045112. Epub 2015 Oct 8.


FOXP3(+) Treg Cells and Gender Bias in Autoimmune Diseases.

Nie J, Li YY, Zheng SG, Tsun A, Li B.

Front Immunol. 2015 Sep 28;6:493. doi: 10.3389/fimmu.2015.00493. eCollection 2015. Review.


Targeting Treg signaling for the treatment of autoimmune diseases.

Spence A, Klementowicz JE, Bluestone JA, Tang Q.

Curr Opin Immunol. 2015 Dec;37:11-20. doi: 10.1016/j.coi.2015.09.002. Epub 2015 Sep 29. Review.


Requirement for CD28 in Effector Regulatory T Cell Differentiation, CCR6 Induction, and Skin Homing.

Zhang R, Borges CM, Fan MY, Harris JE, Turka LA.

J Immunol. 2015 Nov 1;195(9):4154-61. doi: 10.4049/jimmunol.1500945. Epub 2015 Sep 25.


Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH.

J Exp Med. 2015 Sep 21;212(10):1603-21. doi: 10.1084/jem.20141030. Epub 2015 Sep 14.


Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.

Sekiya T, Kondo T, Shichita T, Morita R, Ichinose H, Yoshimura A.

J Exp Med. 2015 Sep 21;212(10):1623-40. doi: 10.1084/jem.20142088. Epub 2015 Aug 24.

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