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Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence.

Fridley BL, Ghosh TM, Wang A, Raghavan R, Dai J, Goode EL, Lamba JK.

Front Genet. 2016 Mar 22;7:37. doi: 10.3389/fgene.2016.00037. eCollection 2016.


Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation.

Ho MF, Bongartz T, Liu M, Kalari KR, Goss PE, Shepherd LE, Goetz MP, Kubo M, Ingle JN, Wang L, Weinshilboum RM.

Mol Endocrinol. 2016 Mar;30(3):382-98. doi: 10.1210/me.2015-1267. Epub 2016 Feb 11.


Computational discovery of transcription factors associated with drug response.

Hanson C, Cairns J, Wang L, Sinha S.

Pharmacogenomics J. 2015 Oct 27. doi: 10.1038/tpj.2015.74. [Epub ahead of print]


Transcriptomic Signatures of Auger Electron Radioimmunotherapy Using Nuclear Targeting (111)In-Trastuzumab for Potential Combination Therapies.

Li HK, Morokoshi Y, Daino K, Furukawa T, Kamada T, Saga T, Hasegawa S.

Cancer Biother Radiopharm. 2015 Oct;30(8):349-58. doi: 10.1089/cbr.2015.1882.


Mutations of the human interferon alpha-2b (hIFN╬▒-2b) gene in cancer patients receiving radiotherapy.

Shahid S, Chaudhry MN, Mahmood N.

Am J Cancer Res. 2015 Jul 15;5(8):2455-66. eCollection 2015.


Bora downregulation results in radioresistance by promoting repair of double strand breaks.

Cairns J, Peng Y, Yee VC, Lou Z, Wang L.

PLoS One. 2015 Mar 5;10(3):e0119208. doi: 10.1371/journal.pone.0119208. eCollection 2015.


In vitro human cell line models to predict clinical response to anticancer drugs.

Niu N, Wang L.

Pharmacogenomics. 2015;16(3):273-85. doi: 10.2217/pgs.14.170. Review.


Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs).

Tong Y, Niu N, Jenkins G, Batzler A, Li L, Kalari KR, Wang L.

Front Genet. 2015 Jan 13;5:465. doi: 10.3389/fgene.2014.00465. eCollection 2014.


Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease.

Peprah E, Xu H, Tekola-Ayele F, Royal CD.

Public Health Genomics. 2015;18(1):40-51. Epub 2014 Nov 26. Review.


Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Liu M, Goss PE, Ingle JN, Kubo M, Furukawa Y, Batzler A, Jenkins GD, Carlson EE, Nakamura Y, Schaid DJ, Chapman JA, Shepherd LE, Ellis MJ, Khosla S, Wang L, Weinshilboum RM.

Mol Endocrinol. 2014 Oct;28(10):1740-51. doi: 10.1210/me.2014-1147. Epub 2014 Aug 22.


Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer.

Pu X, Wang L, Chang JY, Hildebrandt MA, Ye Y, Lu C, Skinner HD, Niu N, Jenkins GD, Komaki R, Minna JD, Roth JA, Weinshilboum RM, Wu X.

Clin Pharmacol Ther. 2014 Nov;96(5):609-15. doi: 10.1038/clpt.2014.154. Epub 2014 Jul 23.


Radiation-induced apoptosis varies among individuals and is modified by sex and age.

Applebaum MA, Skol AD, Bond EE, Overholtzer M, Bond GL, Onel K.

Int J Radiat Biol. 2014 Oct;90(10):903-8. doi: 10.3109/09553002.2014.925603. Epub 2014 Jun 25.


Treatment of Radiation Injury.

Akita S.

Adv Wound Care (New Rochelle). 2014 Jan 1;3(1):1-11. Review.


Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.

Matimba A, Li F, Livshits A, Cartwright CS, Scully S, Fridley BL, Jenkins G, Batzler A, Wang L, Weinshilboum R, Lennard L.

Pharmacogenomics. 2014 Mar;15(4):433-47. doi: 10.2217/pgs.13.226.


Genetic variation is the major determinant of individual differences in leukocyte endothelial adhesion.

Grassi MA, Rao V, Winkler KP, Zhang W, Bogaard JD, Chen S, LaCroix B, Lenkala D, Rehman J, Malik AB, Cox NJ, Huang RS.

PLoS One. 2014 Feb 10;9(2):e87883. doi: 10.1371/journal.pone.0087883. eCollection 2014.


Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

Li L, Fridley BL, Kalari K, Niu N, Jenkins G, Batzler A, Abo RP, Schaid D, Wang L.

BMC Genomics. 2014 Feb 1;15:93. doi: 10.1186/1471-2164-15-93.


Radiogenomics: using genetics to identify cancer patients at risk for development of adverse effects following radiotherapy.

Kerns SL, Ostrer H, Rosenstein BS.

Cancer Discov. 2014 Feb;4(2):155-65. doi: 10.1158/2159-8290.CD-13-0197. Epub 2014 Jan 17. Review.


New aQTL SNPs for the CYP2D6 identified by a novel mediation analysis of genome-wide SNP arrays, gene expression arrays, and CYP2D6 activity.

Jiang G, Chakraborty A, Wang Z, Boustani M, Liu Y, Skaar T, Li L.

Biomed Res Int. 2013;2013:493019. doi: 10.1155/2013/493019. Epub 2013 Oct 22.


Integrative gene set analysis: application to platinum pharmacogenomics.

Fridley BL, Abo R, Tan XL, Jenkins GD, Batzler A, Moyer AM, Biernacka JM, Wang L.

OMICS. 2014 Jan;18(1):34-41. doi: 10.1089/omi.2013.0099. Epub 2013 Nov 7.

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