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Items: 1 to 20 of 22


Is the risk of motor neuron disease increased or decreased after cancer? An Australian case-control study.

Stoyanov A, Pamphlett R.

PLoS One. 2014 Jul 24;9(7):e103572. doi: 10.1371/journal.pone.0103572. eCollection 2014.


Stem cell factor-activated bone marrow ameliorates amyotrophic lateral sclerosis by promoting protective microglial migration.

Terashima T, Kojima H, Urabe H, Yamakawa I, Ogawa N, Kawai H, Chan L, Maegawa H.

J Neurosci Res. 2014 Jul;92(7):856-69.


Microglia centered pathogenesis in ALS: insights in cell interconnectivity.

Brites D, Vaz AR.

Front Cell Neurosci. 2014 May 22;8:117. doi: 10.3389/fncel.2014.00117. eCollection 2014. Review.


Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons.

van Dis V, Kuijpers M, Haasdijk ED, Teuling E, Oakes SA, Hoogenraad CC, Jaarsma D.

Acta Neuropathol Commun. 2014 Apr 7;2:38. doi: 10.1186/2051-5960-2-38.


Species-dependent neuropathology in transgenic SOD1 pigs.

Yang H, Wang G, Sun H, Shu R, Liu T, Wang CE, Liu Z, Zhao Y, Zhao B, Ouyang Z, Yang D, Huang J, Zhou Y, Li S, Jiang X, Xiao Z, Li XJ, Lai L.

Cell Res. 2014 Apr;24(4):464-81. doi: 10.1038/cr.2014.25. Epub 2014 Feb 28.


Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis.

Tan W, Pasinelli P, Trotti D.

Biochim Biophys Acta. 2014 Aug;1842(8):1295-301. doi: 10.1016/j.bbadis.2014.02.009. Epub 2014 Feb 22. Review.


ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.

Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, Roberson ED, Tourtellotte WG, Chen B, Tsai LH, Huang EJ.

J Clin Invest. 2014 Mar;124(3):981-99. doi: 10.1172/JCI72723. Epub 2014 Feb 10.


ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation.

Seijffers R, Zhang J, Matthews JC, Chen A, Tamrazian E, Babaniyi O, Selig M, Hynynen M, Woolf CJ, Brown RH Jr.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1622-7. doi: 10.1073/pnas.1314826111. Epub 2014 Jan 13.


Proteomic analysis reveals differentially regulated protein acetylation in human amyotrophic lateral sclerosis spinal cord.

Liu D, Liu C, Li J, Azadzoi K, Yang Y, Fei Z, Dou K, Kowall NW, Choi HP, Vieira F, Yang JH.

PLoS One. 2013 Dec 2;8(12):e80779. doi: 10.1371/journal.pone.0080779. eCollection 2013.


Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis.

Westphal D, Kluck RM, Dewson G.

Cell Death Differ. 2014 Feb;21(2):196-205. doi: 10.1038/cdd.2013.139. Epub 2013 Oct 25. Review.


Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?

Muyderman H, Chen T.

Br J Pharmacol. 2014 Apr;171(8):2191-205. doi: 10.1111/bph.12476. Review.


Therapeutic neuroprotective agents for amyotrophic lateral sclerosis.

Pandya RS, Zhu H, Li W, Bowser R, Friedlander RM, Wang X.

Cell Mol Life Sci. 2013 Dec;70(24):4729-45. doi: 10.1007/s00018-013-1415-0. Epub 2013 Jul 18. Review.


IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA.

Science. 2012 Nov 9;338(6108):818-22. doi: 10.1126/science.1226191. Epub 2012 Oct 4.


Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK.

Katz SG, Fisher JK, Correll M, Bronson RT, Ligon KL, Walensky LD.

Oncogene. 2013 Aug 29;32(35):4078-85. doi: 10.1038/onc.2012.421. Epub 2012 Sep 17.


Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis.

Gupta S, Read DE, Deepti A, Cawley K, Gupta A, Oommen D, Verfaillie T, Matus S, Smith MA, Mott JL, Agostinis P, Hetz C, Samali A.

Cell Death Dis. 2012 Jun 28;3:e333. doi: 10.1038/cddis.2012.74.


Axonal degeneration as a therapeutic target in the CNS.

Lingor P, Koch JC, Tönges L, Bähr M.

Cell Tissue Res. 2012 Jul;349(1):289-311. doi: 10.1007/s00441-012-1362-3. Epub 2012 Mar 6. Review.


Glial-derived prodegenerative signaling in the Drosophila neuromuscular system.

Keller LC, Cheng L, Locke CJ, Müller M, Fetter RD, Davis GW.

Neuron. 2011 Dec 8;72(5):760-75. doi: 10.1016/j.neuron.2011.09.031.


Protein misdirection inside and outside motor neurons in Amyotrophic Lateral Sclerosis (ALS): a possible clue for therapeutic strategies.

Ido A, Fukuyama H, Urushitani M.

Int J Mol Sci. 2011;12(10):6980-7003. doi: 10.3390/ijms12106980. Epub 2011 Oct 19. Review.


Neuroprotection in metabolism-based therapy.

Hartman AL.

Epilepsy Res. 2012 Jul;100(3):286-94. doi: 10.1016/j.eplepsyres.2011.04.016. Epub 2011 Aug 26. Review.


Modeling mitochondrial dysfunctions in the brain: from mice to men.

Breuer ME, Willems PH, Russel FG, Koopman WJ, Smeitink JA.

J Inherit Metab Dis. 2012 Mar;35(2):193-210. doi: 10.1007/s10545-011-9375-8. Epub 2011 Jul 14. Review.

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