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Results: 13

1.

Probabilistic drug connectivity mapping.

Parkkinen JA, Kaski S.

BMC Bioinformatics. 2014 Apr 17;15:113. doi: 10.1186/1471-2105-15-113.

PMID:
24742351
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Metabolic effects of acute thiamine depletion are reversed by rapamycin in breast and leukemia cells.

Liu S, Miriyala S, Keaton MA, Jordan CT, Wiedl C, Clair DK, Moscow JA.

PLoS One. 2014 Jan 15;9(1):e85702. doi: 10.1371/journal.pone.0085702. eCollection 2014.

PMID:
24454921
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.

Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML.

Chem Biol. 2013 Nov 21;20(11):1352-63. doi: 10.1016/j.chembiol.2013.09.014. Epub 2013 Oct 31.

PMID:
24183972
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Integrative radiogenomic profiling of squamous cell lung cancer.

Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M.

Cancer Res. 2013 Oct 15;73(20):6289-98. doi: 10.1158/0008-5472.CAN-13-1616. Epub 2013 Aug 26.

PMID:
23980093
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells.

Xu Y, Fang F, Miriyala S, Crooks PA, Oberley TD, Chaiswing L, Noel T, Holley AK, Zhao Y, Kiningham KK, Clair DK, Clair WH.

Cancer Res. 2013 Jul 15;73(14):4406-17. doi: 10.1158/0008-5472.CAN-12-4297. Epub 2013 May 14.

PMID:
23674500
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.

Sen S, Hassane DC, Corbett C, Becker MW, Jordan CT, Guzman ML.

Exp Hematol. 2013 Sep;41(9):799-807.e4. doi: 10.1016/j.exphem.2013.04.012. Epub 2013 May 6.

PMID:
23660068
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia.

Chiarini F, Lonetti A, Teti G, Orsini E, Bressanin D, Cappellini A, Ricci F, Tazzari PL, Ognibene A, Falconi M, Pagliaro P, Iacobucci I, Martinelli G, Amadori S, McCubrey JA, Martelli AM.

Oncotarget. 2012 Dec;3(12):1615-28.

PMID:
23271044
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.

Czyz M, Koprowska K, Sztiller-Sikorska M.

Cancer Biol Ther. 2013 Feb;14(2):135-45. doi: 10.4161/cbt.22952. Epub 2012 Nov 28.

PMID:
23192276
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Transcriptional data: a new gateway to drug repositioning?

Iorio F, Rittman T, Ge H, Menden M, Saez-Rodriguez J.

Drug Discov Today. 2013 Apr;18(7-8):350-7. doi: 10.1016/j.drudis.2012.07.014. Epub 2012 Aug 7.

PMID:
22897878
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.

Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT.

Cell Stem Cell. 2012 Sep 7;11(3):359-72. doi: 10.1016/j.stem.2012.05.024. Epub 2012 Aug 2.

PMID:
22863534
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic and proteomic approaches to identify cancer drug targets.

Roti G, Stegmaier K.

Br J Cancer. 2012 Jan 17;106(2):254-61. doi: 10.1038/bjc.2011.543. Epub 2011 Dec 13. Review.

PMID:
22166799
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, as (19)f NMR probes in deuterium-free environments.

Woods JR, Mo H, Bieberich AA, Alavanja T, Colby DA.

J Med Chem. 2011 Nov 24;54(22):7934-41. doi: 10.1021/jm201114t. Epub 2011 Oct 27.

PMID:
22029741
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Breast cancer stem cells, cytokine networks, and the tumor microenvironment.

Korkaya H, Liu S, Wicha MS.

J Clin Invest. 2011 Oct;121(10):3804-9. doi: 10.1172/JCI57099. Epub 2011 Oct 3. Review.

PMID:
21965337
[PubMed - indexed for MEDLINE]
Free PMC Article
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