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Items: 1 to 20 of 88

1.

Network science for the identification of novel therapeutic targets in epilepsy.

Scott RC.

F1000Res. 2016 May 16;5. pii: F1000 Faculty Rev-893. doi: 10.12688/f1000research.8214.1. eCollection 2016. Review.

2.

Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.

Abdelmagid N, Bereczky-Veress B, Atanur S, Musilová A, Zídek V, Saba L, Warnecke A, Khademi M, Studahl M, Aurelius E, Hjalmarsson A, Garcia-Diaz A, Denis CV, Bergström T, Sköldenberg B, Kockum I, Aitman T, Hübner N, Olsson T, Pravenec M, Diez M.

PLoS One. 2016 May 25;11(5):e0155832. doi: 10.1371/journal.pone.0155832. eCollection 2016.

3.

The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages.

Rutkowska A, O'Sullivan SA, Christen I, Zhang J, Sailer AW, Dev KK.

Sci Rep. 2016 May 11;6:25520. doi: 10.1038/srep25520.

4.

Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility.

Ram R, Mehta M, Nguyen QT, Larma I, Boehm BO, Pociot F, Concannon P, Morahan G.

J Immunol. 2016 Apr 1;196(7):3043-53. doi: 10.4049/jimmunol.1502056. Epub 2016 Feb 24.

PMID:
26912320
5.

Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression.

Rakitsch B, Stegle O.

Genome Biol. 2016 Feb 24;17:33. doi: 10.1186/s13059-016-0895-2.

6.

Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics.

Lamparter D, Marbach D, Rueedi R, Kutalik Z, Bergmann S.

PLoS Comput Biol. 2016 Jan 25;12(1):e1004714. doi: 10.1371/journal.pcbi.1004714. eCollection 2016 Jan.

7.

Cofunctional Subpathways Were Regulated by Transcription Factor with Common Motif, Common Family, or Common Tissue.

Su F, Shang D, Xu Y, Feng L, Yang H, Liu B, Su S, Chen L, Li X.

Biomed Res Int. 2015;2015:780357. doi: 10.1155/2015/780357. Epub 2015 Nov 24.

8.

MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues.

Lewin A, Saadi H, Peters JE, Moreno-Moral A, Lee JC, Smith KG, Petretto E, Bottolo L, Richardson S.

Bioinformatics. 2016 Feb 15;32(4):523-32. doi: 10.1093/bioinformatics/btv568. Epub 2015 Oct 26.

9.

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

Bentham J, Morris DL, Cunninghame Graham DS, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC, Rönnblom L, Graham RR, Wither JE, Rioux JD, Alarcón-Riquelme ME, Vyse TJ.

Nat Genet. 2015 Dec;47(12):1457-64. doi: 10.1038/ng.3434. Epub 2015 Oct 26.

10.

Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis.

Nevius E, Pinho F, Dhodapkar M, Jin H, Nadrah K, Horowitz MC, Kikuta J, Ishii M, Pereira JP.

J Exp Med. 2015 Oct 19;212(11):1931-46. doi: 10.1084/jem.20150088. Epub 2015 Oct 5.

11.

G protein-coupled receptor 183 facilitates endothelial-to-hematopoietic transition via Notch1 inhibition.

Zhang P, He Q, Chen D, Liu W, Wang L, Zhang C, Ma D, Li W, Liu B, Liu F.

Cell Res. 2015 Oct;25(10):1093-107. doi: 10.1038/cr.2015.109. Epub 2015 Sep 11.

12.

Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages.

Christofidou P, Nelson CP, Nikpay M, Qu L, Li M, Loley C, Debiec R, Braund PS, Denniff M, Charchar FJ, Arjo AR, Trégouët DA, Goodall AH, Cambien F, Ouwehand WH, Roberts R, Schunkert H, Hengstenberg C, Reilly MP, Erdmann J, McPherson R, König IR, Thompson JR, Samani NJ, Tomaszewski M.

Am J Hum Genet. 2015 Aug 6;97(2):228-37. doi: 10.1016/j.ajhg.2015.06.001. Epub 2015 Jul 9.

13.

Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study.

Poitou C, Perret C, Mathieu F, Truong V, Blum Y, Durand H, Alili R, Chelghoum N, Pelloux V, Aron-Wisnewsky J, Torcivia A, Bouillot JL, Parks BW, Ninio E, Clément K, Tiret L.

PLoS One. 2015 May 4;10(5):e0125718. doi: 10.1371/journal.pone.0125718. eCollection 2015.

14.

7α, 25-dihydroxycholesterol-mediated activation of EBI2 in immune regulation and diseases.

Sun S, Liu C.

Front Pharmacol. 2015 Mar 24;6:60. doi: 10.3389/fphar.2015.00060. eCollection 2015. Review.

15.

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium, Todd JA, Wallace C, Concannon P, Rich SS.

Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9.

16.

Type 1 diabetes and gut microbiota: Friend or foe?

Hu C, Wong FS, Wen L.

Pharmacol Res. 2015 Aug;98:9-15. doi: 10.1016/j.phrs.2015.02.006. Epub 2015 Mar 5. Review.

PMID:
25747961
17.

Network representations of immune system complexity.

Subramanian N, Torabi-Parizi P, Gottschalk RA, Germain RN, Dutta B.

Wiley Interdiscip Rev Syst Biol Med. 2015 Jan-Feb;7(1):13-38. doi: 10.1002/wsbm.1288. Epub 2015 Jan 27. Review.

18.

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.

Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PL, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E.

Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031.

19.

Type I diabetes mellitus: genetic factors and presumptive enteroviral etiology or protection.

Precechtelova J, Borsanyiova M, Sarmirova S, Bopegamage S.

J Pathog. 2014;2014:738512. doi: 10.1155/2014/738512. Epub 2014 Dec 10. Review.

20.

Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease.

Johnson MD, Mueller M, Adamowicz-Brice M, Collins MJ, Gellert P, Maratou K, Srivastava PK, Rotival M, Butt S, Game L, Atanur SS, Silver N, Norsworthy PJ, Langley SR, Petretto E, Pravenec M, Aitman TJ.

PLoS Genet. 2014 Dec 4;10(12):e1004813. doi: 10.1371/journal.pgen.1004813. eCollection 2014 Dec.

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