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Items: 1 to 20 of 47

1.

A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit.

Cundell MJ, Hutter LH, Nunes Bastos R, Poser E, Holder J, Mohammed S, Novak B, Barr FA.

J Cell Biol. 2016 Aug 29;214(5):539-54. doi: 10.1083/jcb.201606033. Epub 2016 Aug 22.

PMID:
27551054
2.

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.

Campbell J, Ryan CJ, Brough R, Bajrami I, Pemberton HN, Chong IY, Costa-Cabral S, Frankum J, Gulati A, Holme H, Miller R, Postel-Vinay S, Rafiq R, Wei W, Williamson CT, Quigley DA, Tym J, Al-Lazikani B, Fenton T, Natrajan R, Strauss SJ, Ashworth A, Lord CJ.

Cell Rep. 2016 Mar 15;14(10):2490-501. doi: 10.1016/j.celrep.2016.02.023. Epub 2016 Mar 3.

3.

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

Voets E, Marsman J, Demmers J, Beijersbergen R, Wolthuis R.

Sci Rep. 2015 Oct 1;5:14798. doi: 10.1038/srep14798.

4.

Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes.

Pfender S, Kuznetsov V, Pasternak M, Tischer T, Santhanam B, Schuh M.

Nature. 2015 Aug 13;524(7564):239-42. doi: 10.1038/nature14568. Epub 2015 Jul 6.

5.

LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential.

Hong CS, Ho W, Zhang C, Yang C, Elder JB, Zhuang Z.

Cancer Biol Ther. 2015;16(6):821-33. doi: 10.1080/15384047.2015.1040961. Epub 2015 Apr 21. Review.

6.

MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C.

Voets E, Wolthuis R.

Biol Open. 2015 Mar 6;4(4):484-95. doi: 10.1242/bio.201410793.

7.

Entry into mitosis: a solution to the decades-long enigma of MPF.

Kishimoto T.

Chromosoma. 2015 Dec;124(4):417-28. doi: 10.1007/s00412-015-0508-y. Epub 2015 Feb 25. Review.

8.

Increased ARPP-19 expression is associated with hepatocellular carcinoma.

Song H, Pan J, Liu Y, Wen H, Wang L, Cui J, Liu Y, Hu B, Yao Z, Ji G.

Int J Mol Sci. 2014 Dec 24;16(1):178-92. doi: 10.3390/ijms16010178.

9.

Inefficient degradation of cyclin B1 re-activates the spindle checkpoint right after sister chromatid disjunction.

Clijsters L, van Zon W, Riet BT, Voets E, Boekhout M, Ogink J, Rumpf-Kienzl C, Wolthuis RM.

Cell Cycle. 2014;13(15):2370-8. doi: 10.4161/cc.29336.

10.

Regulation of Greatwall kinase by protein stabilization and nuclear localization.

Yamamoto TM, Wang L, Fisher LA, Eckerdt FD, Peng A.

Cell Cycle. 2014;13(22):3565-75. doi: 10.4161/15384101.2014.962942.

11.

Mastl kinase, a promising therapeutic target, promotes cancer recurrence.

Wang L, Luong VQ, Giannini PJ, Peng A.

Oncotarget. 2014 Nov 30;5(22):11479-89.

12.

Hybrid and rogue kinases encoded in the genomes of model eukaryotes.

Rakshambikai R, Gnanavel M, Srinivasan N.

PLoS One. 2014 Sep 25;9(9):e107956. doi: 10.1371/journal.pone.0107956. eCollection 2014.

13.

Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II.

Adhikari D, Diril MK, Busayavalasa K, Risal S, Nakagawa S, Lindkvist R, Shen Y, Coppola V, Tessarollo L, Kudo NR, Kaldis P, Liu K.

J Cell Biol. 2014 Sep 29;206(7):843-53. doi: 10.1083/jcb.201406033. Epub 2014 Sep 22.

14.

Phosphatase 1 nuclear targeting subunit is an essential regulator of M-phase entry, maintenance, and exit.

Fisher LA, Wang L, Wu L, Peng A.

J Biol Chem. 2014 Aug 22;289(34):23745-52. doi: 10.1074/jbc.M114.572149. Epub 2014 Jul 7.

15.

α-endosulfine (ENSA) regulates exit from prophase I arrest in mouse oocytes.

Matthews LM, Evans JP.

Cell Cycle. 2014;13(10):1639-49. doi: 10.4161/cc.28606. Epub 2014 Mar 25.

16.

Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events.

McCloy RA, Rogers S, Caldon CE, Lorca T, Castro A, Burgess A.

Cell Cycle. 2014;13(9):1400-12. doi: 10.4161/cc.28401. Epub 2014 Mar 6.

17.

Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers.

Williams BC, Filter JJ, Blake-Hodek KA, Wadzinski BE, Fuda NJ, Shalloway D, Goldberg ML.

Elife. 2014 Mar 11;3:e01695. doi: 10.7554/eLife.01695.

18.

Cyclin B-Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase-independent mechanism.

Okumura E, Morita A, Wakai M, Mochida S, Hara M, Kishimoto T.

J Cell Biol. 2014 Mar 17;204(6):881-9. doi: 10.1083/jcb.201307160. Epub 2014 Mar 10.

19.

PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.

Hégarat N, Vesely C, Vinod PK, Ocasio C, Peter N, Gannon J, Oliver AW, Novák B, Hochegger H.

PLoS Genet. 2014 Jan;10(1):e1004004. doi: 10.1371/journal.pgen.1004004. Epub 2014 Jan 2. Erratum in: PLoS Genet. 2014 Feb;10(2):e1004259.

20.

Robust mitotic entry is ensured by a latching switch.

Tuck C, Zhang T, Potapova T, Malumbres M, Novák B.

Biol Open. 2013 Jul 26;2(9):924-31. doi: 10.1242/bio.20135199. eCollection 2013.

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