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Items: 1 to 20 of 22


Cancer as a channelopathy: ion channels and pumps in tumor development and progression.

Litan A, Langhans SA.

Front Cell Neurosci. 2015 Mar 17;9:86. doi: 10.3389/fncel.2015.00086. eCollection 2015. Review.


High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.

Rabjerg M, Oliván-Viguera A, Hansen LK, Jensen L, Sevelsted-Møller L, Walter S, Jensen BL, Marcussen N, Köhler R.

PLoS One. 2015 Apr 7;10(4):e0122992. doi: 10.1371/journal.pone.0122992. eCollection 2015.


Involvement of large-conductance Ca2+-activated K+ channels in chloroquine-induced force alterations in pre-contracted airway smooth muscle.

Wei MY, Xue L, Tan L, Sai WB, Liu XC, Jiang QJ, Shen J, Peng YB, Zhao P, Yu MF, Chen W, Ma LQ, Zhai K, Zou C, Guo D, Qin G, Zheng YM, Wang YX, Ji G, Liu QH.

PLoS One. 2015 Mar 30;10(3):e0121566. doi: 10.1371/journal.pone.0121566. eCollection 2015.


The large conductance Ca(2+) -activated K(+) (BKCa) channel regulates cell proliferation in SH-SY5Y neuroblastoma cells by activating the staurosporine-sensitive protein kinases.

Curci A, Mele A, Camerino GM, Dinardo MM, Tricarico D.

Front Physiol. 2014 Dec 9;5:476. doi: 10.3389/fphys.2014.00476. eCollection 2014.


Cl- and K+ channels and their role in primary brain tumour biology.

Turner KL, Sontheimer H.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 3;369(1638):20130095. doi: 10.1098/rstb.2013.0095. Print 2014 Mar 19. Review.


Potassium channels in cell cycle and cell proliferation.

Urrego D, Tomczak AP, Zahed F, Stühmer W, Pardo LA.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 3;369(1638):20130094. doi: 10.1098/rstb.2013.0094. Print 2014 Mar 19. Review.


Application of ion-sensitive field effect transistors for ion channel screening.

Walsh KB, DeRoller N, Zhu Y, Koley G.

Biosens Bioelectron. 2014 Apr 15;54:448-54. doi: 10.1016/j.bios.2013.11.038. Epub 2013 Nov 20.


Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors.

Sallam AA, Houssen WE, Gissendanner CR, Orabi KY, Foudah AI, El Sayed KA.

Medchemcomm. 2013 Oct;4(10). doi: 10.1039/C3MD00198A.


KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo.

D'Alessandro G, Catalano M, Sciaccaluga M, Chece G, Cipriani R, Rosito M, Grimaldi A, Lauro C, Cantore G, Santoro A, Fioretti B, Franciolini F, Wulff H, Limatola C.

Cell Death Dis. 2013 Aug 15;4:e773. doi: 10.1038/cddis.2013.279.


TRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activity.

Agarwal JJ, Zhu Y, Zhang QY, Mongin AA, Hough LB.

PLoS One. 2013 May 7;8(5):e63028. doi: 10.1371/journal.pone.0063028. Print 2013.


Novel phenolic inhibitors of small/intermediate-conductance Ca²⁺-activated K⁺ channels, KCa3.1 and KCa2.3.

Oliván-Viguera A, Valero MS, Murillo MD, Wulff H, García-Otín AL, Arbonés-Mainar JM, Köhler R.

PLoS One. 2013;8(3):e58614. doi: 10.1371/journal.pone.0058614. Epub 2013 Mar 14.


STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion.

Motiani RK, Hyzinski-García MC, Zhang X, Henkel MM, Abdullaev IF, Kuo YH, Matrougui K, Mongin AA, Trebak M.

Pflugers Arch. 2013 Sep;465(9):1249-60. doi: 10.1007/s00424-013-1254-8. Epub 2013 Mar 21.


The inhibition of KCa3.1 channels activity reduces cell motility in glioblastoma derived cancer stem cells.

Ruggieri P, Mangino G, Fioretti B, Catacuzzeno L, Puca R, Ponti D, Miscusi M, Franciolini F, Ragona G, Calogero A.

PLoS One. 2012;7(10):e47825. doi: 10.1371/journal.pone.0047825. Epub 2012 Oct 22.


Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels.

Lambertsen KL, Gramsbergen JB, Sivasaravanaparan M, Ditzel N, Sevelsted-Møller LM, Oliván-Viguera A, Rabjerg M, Wulff H, Köhler R.

PLoS One. 2012;7(10):e47744. doi: 10.1371/journal.pone.0047744. Epub 2012 Oct 15.


Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death.

McFerrin MB, Turner KL, Cuddapah VA, Sontheimer H.

Am J Physiol Cell Physiol. 2012 Nov 15;303(10):C1070-8. doi: 10.1152/ajpcell.00040.2012. Epub 2012 Sep 19.


Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas.

Engler JR, Robinson AE, Smirnov I, Hodgson JG, Berger MS, Gupta N, James CD, Molinaro A, Phillips JJ.

PLoS One. 2012;7(8):e43339. doi: 10.1371/journal.pone.0043339. Epub 2012 Aug 22.


Glioma big potassium channel expression in human cancers and possible T cell epitopes for their immunotherapy.

Ge L, Hoa NT, Cornforth AN, Bota DA, Mai A, Kim DI, Chiou SK, Hickey MJ, Kruse CA, Jadus MR.

J Immunol. 2012 Sep 1;189(5):2625-34. doi: 10.4049/jimmunol.1102965. Epub 2012 Jul 27.


Expression and Role of the Intermediate-Conductance Calcium-Activated Potassium Channel KCa3.1 in Glioblastoma.

Catacuzzeno L, Fioretti B, Franciolini F.

J Signal Transduct. 2012;2012:421564. doi: 10.1155/2012/421564. Epub 2012 May 17.


Activation of BK(Ca) channels in zoledronic acid-induced apoptosis of MDA-MB-231 breast cancer cells.

Ma YG, Liu WC, Dong S, Du C, Wang XJ, Li JS, Xie XP, Wu L, Ma DC, Yu ZB, Xie MJ.

PLoS One. 2012;7(5):e37451. doi: 10.1371/journal.pone.0037451. Epub 2012 May 24.


Ion channels in glioblastoma.

Molenaar RJ.

ISRN Neurol. 2011;2011:590249. doi: 10.5402/2011/590249. Epub 2011 Nov 29.

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