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Results: 1 to 20 of 76

1.

Stress granule-defective mutants deregulate stress responsive transcripts.

Yang X, Shen Y, Garre E, Hao X, Krumlinde D, Cvijović M, Arens C, Nyström T, Liu B, Sunnerhagen P.

PLoS Genet. 2014 Nov 6;10(11):e1004763. doi: 10.1371/journal.pgen.1004763. eCollection 2014 Nov.

PMID:
25375155
[PubMed - in process]
Free PMC Article
2.

RNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress response.

Zhang T, Baldie G, Periz G, Wang J.

PLoS Genet. 2014 Oct 16;10(10):e1004693. doi: 10.1371/journal.pgen.1004693. eCollection 2014 Oct.

PMID:
25329970
[PubMed - in process]
Free PMC Article
3.

Functions of FUS/TLS from DNA repair to stress response: implications for ALS.

Sama RR, Ward CL, Bosco DA.

ASN Neuro. 2014 Jun 1;6(4). pii: 1759091414544472. doi: 10.1177/1759091414544472.

PMID:
25289647
[PubMed - in process]
Free PMC Article
4.

FUS-regulated RNA metabolism and DNA damage repair: Implications for amyotrophic lateral sclerosis and frontotemporal dementia pathogenesis.

Zhou Y, Liu S, Oztürk A, Hicks GG.

Rare Dis. 2014 Jun 12;2:e29515. doi: 10.4161/rdis.29515. eCollection 2014.

PMID:
25083344
[PubMed]
Free PMC Article
5.

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.

Schwartz JC, Podell ER, Han SS, Berry JD, Eggan KC, Cech TR.

Mol Biol Cell. 2014 Sep 1;25(17):2571-8. doi: 10.1091/mbc.E14-05-1007. Epub 2014 Jul 9.

PMID:
25009283
[PubMed - in process]
Free PMC Article
6.

Fishing for causes and cures of motor neuron disorders.

Patten SA, Armstrong GA, Lissouba A, Kabashi E, Parker JA, Drapeau P.

Dis Model Mech. 2014 Jul;7(7):799-809. doi: 10.1242/dmm.015719.

PMID:
24973750
[PubMed - in process]
Free PMC Article
7.

Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics.

Figley MD, Bieri G, Kolaitis RM, Taylor JP, Gitler AD.

J Neurosci. 2014 Jun 11;34(24):8083-97. doi: 10.1523/JNEUROSCI.0543-14.2014.

PMID:
24920614
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells.

Acosta JR, Goldsbury C, Winnick C, Badrock AP, Fraser ST, Laird AS, Hall TE, Don EK, Fifita JA, Blair IP, Nicholson GA, Cole NJ.

PLoS One. 2014 Jun 9;9(6):e90572. doi: 10.1371/journal.pone.0090572. eCollection 2014.

PMID:
24912067
[PubMed - in process]
Free PMC Article
9.

FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage.

Deng Q, Holler CJ, Taylor G, Hudson KF, Watkins W, Gearing M, Ito D, Murray ME, Dickson DW, Seyfried NT, Kukar T.

J Neurosci. 2014 Jun 4;34(23):7802-13. doi: 10.1523/JNEUROSCI.0172-14.2014.

PMID:
24899704
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases.

Ayers JI, Xu G, Pletnikova O, Troncoso JC, Hart PJ, Borchelt DR.

Acta Neuropathol Commun. 2014 May 14;2:55. doi: 10.1186/2051-5960-2-55.

PMID:
24887207
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans.

Therrien M, Parker JA.

Front Genet. 2014 Apr 17;5:85. doi: 10.3389/fgene.2014.00085. eCollection 2014. Review.

PMID:
24860590
[PubMed]
Free PMC Article
12.

Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms.

Shelkovnikova TA, Robinson HK, Southcombe JA, Ninkina N, Buchman VL.

Hum Mol Genet. 2014 Oct 1;23(19):5211-26. doi: 10.1093/hmg/ddu243. Epub 2014 May 19.

PMID:
24842888
[PubMed - in process]
Free PMC Article
13.

Pu-erh tea extract induces the degradation of FET family proteins involved in the pathogenesis of amyotrophic lateral sclerosis.

Yu Y, Hayashi S, Cai X, Fang C, Shi W, Tsutsui H, Sheng J.

Biomed Res Int. 2014;2014:254680. doi: 10.1155/2014/254680. Epub 2014 Apr 7.

PMID:
24804206
[PubMed - in process]
Free PMC Article
14.

Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue.

Heck MV, Azizov M, Stehning T, Walter M, Kedersha N, Auburger G.

Neurogenetics. 2014 May;15(2):135-44.

PMID:
24659297
[PubMed - in process]
Free PMC Article
15.

ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor.

Liu-Yesucevitz L, Lin AY, Ebata A, Boon JY, Reid W, Xu YF, Kobrin K, Murphy GJ, Petrucelli L, Wolozin B.

J Neurosci. 2014 Mar 19;34(12):4167-74. doi: 10.1523/JNEUROSCI.2350-13.2014.

PMID:
24647938
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules.

Yasuda K, Zhang H, Loiselle D, Haystead T, Macara IG, Mili S.

J Cell Biol. 2013 Dec 9;203(5):737-46. doi: 10.1083/jcb.201306058. Epub 2013 Dec 2.

PMID:
24297750
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation.

Zhou Y, Liu S, Liu G, Oztürk A, Hicks GG.

PLoS Genet. 2013 Oct;9(10):e1003895. doi: 10.1371/journal.pgen.1003895. Epub 2013 Oct 31.

PMID:
24204307
[PubMed - in process]
Free PMC Article
18.

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.

Baron DM, Kaushansky LJ, Ward CL, Sama RR, Chian RJ, Boggio KJ, Quaresma AJ, Nickerson JA, Bosco DA.

Mol Neurodegener. 2013 Aug 31;8:30. doi: 10.1186/1750-1326-8-30.

PMID:
24090136
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ewing sarcoma protein: a key player in human cancer.

Paronetto MP.

Int J Cell Biol. 2013;2013:642853. doi: 10.1155/2013/642853. Epub 2013 Sep 3. Review.

PMID:
24082883
[PubMed]
Free PMC Article
20.

Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.

Shelkovnikova TA, Robinson HK, Connor-Robson N, Buchman VL.

Cell Cycle. 2013 Oct 1;12(19):3194-202. doi: 10.4161/cc.26241. Epub 2013 Sep 4.

PMID:
24013423
[PubMed - indexed for MEDLINE]
Free PMC Article

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