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Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells.

Kalantari R, Hicks JA, Li L, Gagnon KT, Sridhara V, Lemoff A, Mirzaei H, Corey DR.

RNA. 2016 Jul;22(7):1085-98. doi: 10.1261/rna.056499.116. Epub 2016 May 19.


RNA Activation of the Vascular Endothelial Growth Factor Gene (VEGF) Promoter by Double-Stranded RNA and Hypoxia: Role of Noncoding VEGF Promoter Transcripts.

Lopez P, Wagner KD, Hofman P, Van Obberghen E.

Mol Cell Biol. 2016 May 2;36(10):1480-93. doi: 10.1128/MCB.01096-15. Print 2016 May 15.


Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics.

Matsui M, Prakash TP, Corey DR.

Mol Ther. 2016 May;24(5):946-55. doi: 10.1038/mt.2016.39. Epub 2016 Feb 23.


saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription.

Portnoy V, Lin SH, Li KH, Burlingame A, Hu ZH, Li H, Li LC.

Cell Res. 2016 Mar;26(3):320-35. doi: 10.1038/cr.2016.22. Epub 2016 Feb 23.


Small activating RNA binds to the genomic target site in a seed-region-dependent manner.

Meng X, Jiang Q, Chang N, Wang X, Liu C, Xiong J, Cao H, Liang Z.

Nucleic Acids Res. 2016 Mar 18;44(5):2274-82. doi: 10.1093/nar/gkw076. Epub 2016 Feb 11.


Activating frataxin expression by repeat-targeted nucleic acids.

Li L, Matsui M, Corey DR.

Nat Commun. 2016 Feb 4;7:10606. doi: 10.1038/ncomms10606.


Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions.

Stojic L, Niemczyk M, Orjalo A, Ito Y, Ruijter AE, Uribe-Lewis S, Joseph N, Weston S, Menon S, Odom DT, Rinn J, Gergely F, Murrell A.

Nat Commun. 2016 Feb 2;7:10406. doi: 10.1038/ncomms10406.


Cell Type- and Tissue Context-dependent Nuclear Distribution of Human Ago2.

Sharma NR, Wang X, Majerciak V, Ajiro M, Kruhlak M, Meyers C, Zheng ZM.

J Biol Chem. 2016 Jan 29;291(5):2302-9. doi: 10.1074/jbc.C115.695049. Epub 2015 Dec 23.


Regulation of mammalian transcription and splicing by Nuclear RNAi.

Kalantari R, Chiang CM, Corey DR.

Nucleic Acids Res. 2016 Jan 29;44(2):524-37. doi: 10.1093/nar/gkv1305. Epub 2015 Nov 26. Review.


Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.

Lennox KA, Behlke MA.

Nucleic Acids Res. 2016 Jan 29;44(2):863-77. doi: 10.1093/nar/gkv1206. Epub 2015 Nov 17.


Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus.

Méndez C, Ahlenstiel CL, Kelleher AD.

World J Virol. 2015 Aug 12;4(3):219-44. doi: 10.5501/wjv.v4.i3.219. Review.


Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.

Matsui M, Li L, Janowski BA, Corey DR.

Sci Rep. 2015 Aug 5;5:12855. doi: 10.1038/srep12855.


Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels.

Schraivogel D, Schindler SG, Danner J, Kremmer E, Pfaff J, Hannus S, Depping R, Meister G.

Nucleic Acids Res. 2015 Sep 3;43(15):7447-61. doi: 10.1093/nar/gkv705. Epub 2015 Jul 13.


Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs.

Laham-Karam N, Lalli M, Leinonen N, Ylä-Herttuala S.

Mol Ther Nucleic Acids. 2015 May 19;4:e243. doi: 10.1038/mtna.2015.16.


Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males.

Modzelewski AJ, Hilz S, Crate EA, Schweidenback CT, Fogarty EA, Grenier JK, Freire R, Cohen PE, Grimson A.

J Cell Sci. 2015 Jun 15;128(12):2314-27. doi: 10.1242/jcs.167148. Epub 2015 May 1.


Inducing gene expression by targeting promoter sequences using small activating RNAs.

Wang J, Place RF, Portnoy V, Huang V, Kang MR, Kosaka M, Ho MK, Li LC.

J Biol Methods. 2015 Mar 11;2(1). pii: e14.


ARGONAUTE2 cooperates with SWI/SNF complex to determine nucleosome occupancy at human Transcription Start Sites.

Carissimi C, Laudadio I, Cipolletta E, Gioiosa S, Mihailovich M, Bonaldi T, Macino G, Fulci V.

Nucleic Acids Res. 2015 Feb 18;43(3):1498-512. doi: 10.1093/nar/gku1387. Epub 2015 Jan 20.


Genetic mutation of p53 and suppression of the miR-17∼92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling.

Borkowski R, Du L, Zhao Z, McMillan E, Kosti A, Yang CR, Suraokar M, Wistuba II, Gazdar AF, Minna JD, White MA, Pertsemlidis A.

Cancer Res. 2015 Feb 15;75(4):666-75. doi: 10.1158/0008-5472.CAN-14-1329. Epub 2014 Dec 17.


A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus.

Husso T, Ylä-Herttuala S, Turunen MP.

Mol Ther Nucleic Acids. 2014 Nov 18;3:e197. doi: 10.1038/mtna.2014.48. Review.


The role of antisense long noncoding RNA in small RNA-triggered gene activation.

Zhang X, Li H, Burnett JC, Rossi JJ.

RNA. 2014 Dec;20(12):1916-28. doi: 10.1261/rna.043968.113. Epub 2014 Oct 24.

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