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Items: 19


Role of Nrf2 and Autophagy in Acute Lung Injury.

de la Vega MR, Dodson M, Gross C, Manzour H, Lantz RC, Chapman E, Wang T, Black SM, Garcia JG, Zhang DD.

Curr Pharmacol Rep. 2016 Apr;2(2):91-101. Epub 2016 Feb 6.


Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report.

Zhang X, Zhang Z, Chen S, Zhao D, Zhang F, Hu Z, Xiao F, Ma X.

Exp Ther Med. 2015 Oct;10(4):1293-1296. Epub 2015 Jul 29.


Inflammatory mechanisms of pulmonary injury induced by mustards.

Malaviya R, Sunil VR, Venosa A, Vayas KN, Heck DE, Laskin JD, Laskin DL.

Toxicol Lett. 2016 Feb 26;244:2-7. doi: 10.1016/j.toxlet.2015.10.011. Epub 2015 Oct 23. Review.


Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis.

Venosa A, Malaviya R, Choi H, Gow AJ, Laskin JD, Laskin DL.

Am J Respir Cell Mol Biol. 2016 Mar;54(3):436-46. doi: 10.1165/rcmb.2015-0120OC.


Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody.

Malaviya R, Sunil VR, Venosa A, Verissimo VL, Cervelli JA, Vayas KN, Hall L, Laskin JD, Laskin DL.

Toxicol Sci. 2015 Nov;148(1):71-88. doi: 10.1093/toxsci/kfv161. Epub 2015 Aug 4.


Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.

Yuan Q, Jiang YW, Ma TT, Fang QH, Pan L.

J Inflamm (Lond). 2014 Dec 5;11(1):40. doi: 10.1186/s12950-014-0040-5. eCollection 2014.


Topical nitrogen mustard exposure causes systemic toxic effects in mice.

Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R.

Exp Toxicol Pathol. 2015 Feb;67(2):161-70. doi: 10.1016/j.etp.2014.11.006. Epub 2014 Dec 4.


Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation.

Sunil VR, Vayas KN, Cervelli JA, Malaviya R, Hall L, Massa CB, Gow AJ, Laskin JD, Laskin DL.

Exp Mol Pathol. 2014 Aug;97(1):89-98. doi: 10.1016/j.yexmp.2014.05.009. Epub 2014 Jun 2.


Oxidative stress-induced autophagy: role in pulmonary toxicity.

Malaviya R, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2014 Mar 1;275(2):145-51. doi: 10.1016/j.taap.2013.12.022. Epub 2014 Jan 4. Review.


The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard.

Zheng R, Po I, Mishin V, Black AT, Heck DE, Laskin DL, Sinko PJ, Gerecke DR, Gordon MK, Laskin JD.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):345-55. doi: 10.1016/j.taap.2013.06.025. Epub 2013 Jul 9.


Treatment for sulfur mustard lung injuries; new therapeutic approaches from acute to chronic phase.

Poursaleh Z, Harandi AA, Vahedi E, Ghanei M.

Daru. 2012 Sep 10;20(1):27. doi: 10.1186/2008-2231-20-27.


Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor.

Malaviya R, Venosa A, Hall L, Gow AJ, Sinko PJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 Dec 15;265(3):279-91. doi: 10.1016/j.taap.2012.08.027. Epub 2012 Sep 6.


Inhalation of sulfur mustard causes long-term T cell-dependent inflammation: possible role of Th17 cells in chronic lung pathology.

Mishra NC, Rir-sima-ah J, Grotendorst GR, Langley RJ, Singh SP, Gundavarapu S, Weber WM, Pena-Philippides JC, Duncan MR, Sopori ML.

Int Immunopharmacol. 2012 May;13(1):101-8. doi: 10.1016/j.intimp.2012.03.010. Epub 2012 Mar 28.


Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.

Sunil VR, Shen J, Patel-Vayas K, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 May 15;261(1):22-30. doi: 10.1016/j.taap.2012.03.004. Epub 2012 Mar 14.


Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Sunil VR, Patel-Vayas K, Shen J, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):245-55. doi: 10.1016/j.taap.2010.10.027. Epub 2010 Nov 9.


Macrophages and tissue injury: agents of defense or destruction?

Laskin DL, Sunil VR, Gardner CR, Laskin JD.

Annu Rev Pharmacol Toxicol. 2011;51:267-88. doi: 10.1146/annurev.pharmtox.010909.105812. Review.


Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard.

Sunil VR, Patel KJ, Shen J, Reimer D, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Jan 1;250(1):10-8. doi: 10.1016/j.taap.2010.09.016. Epub 2010 Sep 29.


Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity.

Weinberger B, Laskin JD, Sunil VR, Sinko PJ, Heck DE, Laskin DL.

Pulm Pharmacol Ther. 2011 Feb;24(1):92-9. doi: 10.1016/j.pupt.2010.09.004. Epub 2010 Sep 17. Review.

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