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IL-21 and T Cell Differentiation: Consider the Context.

Tian Y, Zajac AJ.

Trends Immunol. 2016 Aug;37(8):557-68. doi: 10.1016/ Epub 2016 Jul 4. Review.


Generalized Liver- and Blood-Derived CD8+ T-Cell Impairment in Response to Cytokines in Chronic Hepatitis C Virus Infection.

Burke Schinkel SC, Carrasco-Medina L, Cooper CL, Crawley AM.

PLoS One. 2016 Jun 17;11(6):e0157055. doi: 10.1371/journal.pone.0157055. eCollection 2016.


IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia.

Xu A, Bhanumathy KK, Wu J, Ye Z, Freywald A, Leary SC, Li R, Xiang J.

Cell Biosci. 2016 May 6;6:30. doi: 10.1186/s13578-016-0098-2. eCollection 2016.


Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC.

Basher F, Jeng EK, Wong H, Wu J.

Oncotarget. 2016 Jan 5;7(1):814-30. doi: 10.18632/oncotarget.6416.


Stable inhibitory activity of regulatory T cells requires the transcription factor Helios.

Kim HJ, Barnitz RA, Kreslavsky T, Brown FD, Moffett H, Lemieux ME, Kaygusuz Y, Meissner T, Holderried TA, Chan S, Kastner P, Haining WN, Cantor H.

Science. 2015 Oct 16;350(6258):334-9. doi: 10.1126/science.aad0616.


NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors.

Anton OM, Vielkind S, Peterson ME, Tagaya Y, Long EO.

J Immunol. 2015 Nov 15;195(10):4810-21. doi: 10.4049/jimmunol.1500414. Epub 2015 Oct 9.


STAT3 promotes CD1d-mediated lipid antigen presentation by regulating a critical gene in glycosphingolipid biosynthesis.

Iyer AK, Liu J, Gallo RM, Kaplan MH, Brutkiewicz RR.

Immunology. 2015 Nov;146(3):444-55. doi: 10.1111/imm.12521. Epub 2015 Sep 21.


Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.

Maude SL, Dolai S, Delgado-Martin C, Vincent T, Robbins A, Selvanathan A, Ryan T, Hall J, Wood AC, Tasian SK, Hunger SP, Loh ML, Mullighan CG, Wood BL, Hermiston ML, Grupp SA, Lock RB, Teachey DT.

Blood. 2015 Mar 12;125(11):1759-67. doi: 10.1182/blood-2014-06-580480. Epub 2015 Feb 2.


Intersection of mTOR and STAT signaling in immunity.

Saleiro D, Platanias LC.

Trends Immunol. 2015 Jan;36(1):21-9. doi: 10.1016/ Epub 2014 Nov 15. Review.


Regulatory T cells resist virus infection-induced apoptosis.

Che JW, Kraft AR, Selin LK, Welsh RM.

J Virol. 2015 Feb;89(4):2112-20. doi: 10.1128/JVI.02245-14. Epub 2014 Dec 3.


Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins.

Kurtulus S, Sholl A, Toe J, Tripathi P, Raynor J, Li KP, Pellegrini M, Hildeman DA.

Cell Death Differ. 2015 Jan;22(1):174-84. doi: 10.1038/cdd.2014.118. Epub 2014 Aug 15.


Regulation of tissue-dependent differences in CD8+ T cell apoptosis during viral infection.

Kapoor VN, Shin HM, Cho OH, Berg LJ, Kang J, Welsh RM.

J Virol. 2014 Sep 1;88(17):9490-503. doi: 10.1128/JVI.01223-14. Epub 2014 Jun 18.


Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells.

Huang W, Kachapati K, Adams D, Wu Y, Leung PS, Yang GX, Zhang W, Ansari AA, Flavell RA, Gershwin ME, Ridgway WM.

J Autoimmun. 2014 May;50:123-34. doi: 10.1016/j.jaut.2014.01.034. Epub 2014 Feb 18.


Longitudinal analysis of whole blood transcriptomes to explore molecular signatures associated with acute renal allograft rejection.

Shin H, Günther O, Hollander Z, Wilson-McManus JE, Ng RT, Balshaw R, Keown PA, McMaster R, McManus BM, Isbel NM, Knoll G, Tebbutt SJ.

Bioinform Biol Insights. 2014 Jan 22;8:17-33. doi: 10.4137/BBI.S13376.. eCollection 2014.


When Aging Reaches CD4+ T-Cells: Phenotypic and Functional Changes.

Moro-García MA, Alonso-Arias R, López-Larrea C.

Front Immunol. 2013 May 10;4:107. doi: 10.3389/fimmu.2013.00107. eCollection 2013.


Mcl-1 antagonizes Bax/Bak to promote effector CD4(+) and CD8(+) T-cell responses.

Tripathi P, Koss B, Opferman JT, Hildeman DA.

Cell Death Differ. 2013 Aug;20(8):998-1007. doi: 10.1038/cdd.2013.25. Epub 2013 Apr 5.


Disparate roles for STAT5 in primary and secondary CTL responses.

Mitchell DM, Williams MA.

J Immunol. 2013 Apr 1;190(7):3390-8. doi: 10.4049/jimmunol.1202674. Epub 2013 Feb 25.


Role of PI3K/Akt signaling in memory CD8 T cell differentiation.

Kim EH, Suresh M.

Front Immunol. 2013 Feb 1;4:20. doi: 10.3389/fimmu.2013.00020. eCollection 2013.


Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development.

Kurtulus S, Tripathi P, Hildeman DA.

Front Immunol. 2013 Jan 23;3:404. doi: 10.3389/fimmu.2012.00404. eCollection 2012.


Regulating the immune system via IL-15 transpresentation.

Castillo EF, Schluns KS.

Cytokine. 2012 Sep;59(3):479-90. doi: 10.1016/j.cyto.2012.06.017. Epub 2012 Jul 12. Review.

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