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Results: 1 to 20 of 21

1.

Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.

Stanley SA, Barczak AK, Silvis MR, Luo SS, Sogi K, Vokes M, Bray MA, Carpenter AE, Moore CB, Siddiqi N, Rubin EJ, Hung DT.

PLoS Pathog. 2014 Feb 20;10(2):e1003946. doi: 10.1371/journal.ppat.1003946. eCollection 2014 Feb.

PMID:
24586159
[PubMed - in process]
Free PMC Article
2.

Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with Trastuzumab.

Hughes JB, Rødland MS, Hasmann M, Madshus IH, Stang E.

Pharmaceuticals (Basel). 2012 Jun 28;5(7):674-89. doi: 10.3390/ph5070674.

PMID:
24281706
[PubMed]
Free PMC Article
3.

Sym004, a novel anti-EGFR antibody mixture, augments radiation response in human lung and head and neck cancers.

Huang S, Peet CR, Saker J, Li C, Armstrong EA, Kragh M, Pedersen MW, Harari PM.

Mol Cancer Ther. 2013 Dec;12(12):2772-81. doi: 10.1158/1535-7163.MCT-13-0587. Epub 2013 Oct 15.

PMID:
24130052
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.

Donaldson JM, Zer C, Avery KN, Bzymek KP, Horne DA, Williams JC.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17456-61. doi: 10.1073/pnas.1307309110. Epub 2013 Oct 7.

PMID:
24101516
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Vascular endothelial growth factor (VEGF) and platelet (PF-4) factor 4 inputs modulate human microvascular endothelial signaling in a three-dimensional matrix migration context.

Hang TC, Tedford NC, Reddy RJ, Rimchala T, Wells A, White FM, Kamm RD, Lauffenburger DA.

Mol Cell Proteomics. 2013 Dec;12(12):3704-18. doi: 10.1074/mcp.M113.030528. Epub 2013 Sep 9.

PMID:
24023389
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2.

Maron R, Schechter B, Mancini M, Mahlknecht G, Yarden Y, Sela M.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15389-94. doi: 10.1073/pnas.1313857110. Epub 2013 Sep 3.

PMID:
24003140
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

p38 signaling and receptor recycling events in a microfluidic endothelial cell adhesion assay.

Vickers DA, Chory EJ, Harless MC, Murthy SK.

PLoS One. 2013 Jun 7;8(6):e65828. doi: 10.1371/journal.pone.0065828. Print 2013.

PMID:
23762436
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve.

Er EE, Mendoza MC, Mackey AM, Rameh LE, Blenis J.

Sci Signal. 2013 Jun 11;6(279):ra45. doi: 10.1126/scisignal.2004015.

PMID:
23757022
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth.

Mahlknecht G, Maron R, Mancini M, Schechter B, Sela M, Yarden Y.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8170-5. doi: 10.1073/pnas.1302594110. Epub 2013 Apr 29.

PMID:
23630281
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Molecular dynamics simulations of transitions for ECD epidermal growth factor receptors show key differences between human and drosophila forms of the receptors.

Perilla JR, Leahy DJ, Woolf TB.

Proteins. 2013 Jul;81(7):1113-26. doi: 10.1002/prot.24257. Epub 2013 Apr 10.

PMID:
23348956
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR.

Ferraro DA, Gaborit N, Maron R, Cohen-Dvashi H, Porat Z, Pareja F, Lavi S, Lindzen M, Ben-Chetrit N, Sela M, Yarden Y.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1815-20. doi: 10.1073/pnas.1220763110. Epub 2013 Jan 14.

PMID:
23319610
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Rapid conformational epitope mapping of anti-gp120 antibodies with a designed mutant panel displayed on yeast.

Mata-Fink J, Kriegsman B, Yu HX, Zhu H, Hanson MC, Irvine DJ, Wittrup KD.

J Mol Biol. 2013 Jan 23;425(2):444-56. doi: 10.1016/j.jmb.2012.11.010. Epub 2012 Nov 15.

PMID:
23159556
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.

Sukhanova A, Gorin A, Serebriiskii IG, Gabitova L, Zheng H, Restifo D, Egleston BL, Cunningham D, Bagnyukova T, Liu H, Nikonova A, Adams GP, Zhou Y, Yang DH, Mehra R, Burtness B, Cai KQ, Klein-Szanto A, Kratz LE, Kelley RI, Weiner LM, Herman GE, Golemis EA, Astsaturov I.

Cancer Discov. 2013 Jan;3(1):96-111. doi: 10.1158/2159-8290.CD-12-0031. Epub 2012 Nov 2.

PMID:
23125191
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Triepitopic antibody fusions inhibit cetuximab-resistant BRAF and KRAS mutant tumors via EGFR signal repression.

Spangler JB, Manzari MT, Rosalia EK, Chen TF, Wittrup KD.

J Mol Biol. 2012 Sep 28;422(4):532-44. doi: 10.1016/j.jmb.2012.06.014. Epub 2012 Jun 15.

PMID:
22706026
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Impaired degradation followed by enhanced recycling of epidermal growth factor receptor caused by hypo-phosphorylation of tyrosine 1045 in RBE cells.

Gui A, Kobayashi A, Motoyama H, Kitazawa M, Takeoka M, Miyagawa S.

BMC Cancer. 2012 May 16;12:179. doi: 10.1186/1471-2407-12-179.

PMID:
22591401
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Epidermal growth factor receptor downregulation by small heterodimeric binding proteins.

Hackel BJ, Neil JR, White FM, Wittrup KD.

Protein Eng Des Sel. 2012 Feb;25(2):47-57. doi: 10.1093/protein/gzr056. Epub 2011 Dec 9.

PMID:
22160867
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling.

Boersma YL, Chao G, Steiner D, Wittrup KD, Plückthun A.

J Biol Chem. 2011 Dec 2;286(48):41273-85. doi: 10.1074/jbc.M111.293266. Epub 2011 Oct 6.

PMID:
21979953
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Emerging antibody combinations in oncology.

Demarest SJ, Hariharan K, Dong J.

MAbs. 2011 Jul-Aug;3(4):338-51. Epub 2011 Jul 1. Review.

PMID:
21697653
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

New antibody to stop tumor angiogenesis and lymphatic spread by blocking receptor partnering.

McDonald DM.

Cancer Cell. 2010 Dec 14;18(6):541-3. doi: 10.1016/j.ccr.2010.11.030.

PMID:
21156277
[PubMed]
Free PMC Article
20.

Polyclonal immune responses to antigens associated with cancer signaling pathways and new strategies to enhance cancer vaccines.

Clay TM, Osada T, Hartman ZC, Hobeika A, Devi G, Morse MA, Lyerly HK.

Immunol Res. 2011 Apr;49(1-3):235-47. doi: 10.1007/s12026-010-8186-6.

PMID:
21136201
[PubMed - indexed for MEDLINE]
Free PMC Article

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