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Results: 18

1.

Differential Synaptic and Extrasynaptic Glutamate-Receptor Alterations in Striatal Medium-Sized Spiny Neurons of Aged YAC128 Huntington's Disease Mice.

Botelho EP, Wang E, Chen JY, Holley S, Andre V, Cepeda C, Levine MS.

PLoS Curr. 2014 May;6. pii: ecurrents.hd.34957c4f8bd7cb1f5ec47381dfc811c3. doi: 10.1371/currents.hd.34957c4f8bd7cb1f5ec47381dfc811c3.

PMID:
24894506
[PubMed]
Free PMC Article
2.

Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington disease.

Kolodziejczyk K, Parsons MP, Southwell AL, Hayden MR, Raymond LA.

PLoS One. 2014 Apr 11;9(4):e94562. doi: 10.1371/journal.pone.0094562. eCollection 2014.

PMID:
24728353
[PubMed - in process]
Free PMC Article
3.

Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.

Xu Q, Huang S, Song M, Wang CE, Yan S, Liu X, Gaertig MA, Yu SP, Li H, Li S, Li XJ.

J Cell Biol. 2013 Sep 30;202(7):1123-38. doi: 10.1083/jcb.201303146.

PMID:
24081492
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.

Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, Alberch J, Wesseling JF, Pérez-Otaño I.

Nat Med. 2013 Aug;19(8):1030-8. doi: 10.1038/nm.3246. Epub 2013 Jul 14.

PMID:
23852340
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Age-Dependent Resistance to Excitotoxicity in Htt CAG140 Mice and the Effect of Strain Background.

Strong MK, Southwell AL, Yonan JM, Hayden MR, Macgregor GR, Thompson LM, Steward O.

J Huntingtons Dis. 2012 Jan;1(2):221-41. doi: 10.3233/JHD-129005.

PMID:
23833693
[PubMed - in process]
Free PMC Article
6.

Multiple sources of striatal inhibition are differentially affected in Huntington's disease mouse models.

Cepeda C, Galvan L, Holley SM, Rao SP, André VM, Botelho EP, Chen JY, Watson JB, Deisseroth K, Levine MS.

J Neurosci. 2013 Apr 24;33(17):7393-406. doi: 10.1523/JNEUROSCI.2137-12.2013.

PMID:
23616545
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models.

Horne EA, Coy J, Swinney K, Fung S, Cherry AE, Marrs WR, Naydenov AV, Lin YH, Sun X, Keene CD, Grouzmann E, Muchowski P, Bates GP, Mackie K, Stella N.

Eur J Neurosci. 2013 Feb;37(3):429-40. doi: 10.1111/ejn.12045. Epub 2012 Nov 21.

PMID:
23167744
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mouse models of polyglutamine diseases: review and data table. Part I.

Figiel M, Szlachcic WJ, Switonski PM, Gabka A, Krzyzosiak WJ.

Mol Neurobiol. 2012 Oct;46(2):393-429. doi: 10.1007/s12035-012-8315-4. Epub 2012 Sep 7. Review.

PMID:
22956270
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.

Switonski PM, Szlachcic WJ, Gabka A, Krzyzosiak WJ, Figiel M.

Mol Neurobiol. 2012 Oct;46(2):430-66. doi: 10.1007/s12035-012-8316-3. Epub 2012 Sep 4. Review.

PMID:
22944909
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease.

Hickey MA, Zhu C, Medvedeva V, Lerner RP, Patassini S, Franich NR, Maiti P, Frautschy SA, Zeitlin S, Levine MS, Chesselet MF.

Mol Neurodegener. 2012 Apr 4;7:12. doi: 10.1186/1750-1326-7-12.

PMID:
22475209
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease.

Yuen EY, Wei J, Zhong P, Yan Z.

Neurobiol Dis. 2012 May;46(2):497-502. doi: 10.1016/j.nbd.2012.02.015. Epub 2012 Feb 28.

PMID:
22402331
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease.

Lerner RP, Trejo Martinez Ldel C, Zhu C, Chesselet MF, Hickey MA.

Brain Res Bull. 2012 Apr 10;87(6):571-8. doi: 10.1016/j.brainresbull.2012.01.012. Epub 2012 Feb 4.

PMID:
22326483
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.

Cummings DM, Alaghband Y, Hickey MA, Joshi PR, Hong SC, Zhu C, Ando TK, André VM, Cepeda C, Watson JB, Levine MS.

J Neurophysiol. 2012 Jan;107(2):677-91. doi: 10.1152/jn.00762.2011. Epub 2011 Nov 9.

PMID:
22072510
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease.

Hickey MA, Zhu C, Medvedeva V, Franich NR, Levine MS, Chesselet MF.

Mol Cell Neurosci. 2012 Feb;49(2):149-57. doi: 10.1016/j.mcn.2011.10.007. Epub 2011 Oct 20.

PMID:
22044764
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.

Raymond LA, André VM, Cepeda C, Gladding CM, Milnerwood AJ, Levine MS.

Neuroscience. 2011 Dec 15;198:252-73. doi: 10.1016/j.neuroscience.2011.08.052. Epub 2011 Aug 27. Review.

PMID:
21907762
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

In vivo Dopamine Efflux is Decreased in Striatum of both Fragment (R6/2) and Full-Length (YAC128) Transgenic Mouse Models of Huntington's Disease.

Callahan JW, Abercrombie ED.

Front Syst Neurosci. 2011 Jul 15;5:61. doi: 10.3389/fnsys.2011.00061. eCollection 2011.

PMID:
21811446
[PubMed]
Free PMC Article
17.

Dysregulated Neuronal Activity Patterns Implicate Corticostriatal Circuit Dysfunction in Multiple Rodent Models of Huntington's Disease.

Miller BR, Walker AG, Barton SJ, Rebec GV.

Front Syst Neurosci. 2011 May 9;5:26. doi: 10.3389/fnsys.2011.00026. eCollection 2011.

PMID:
21629717
[PubMed]
Free PMC Article
18.

Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function.

Kim SH, Thomas CA, André VM, Cummings DM, Cepeda C, Levine MS, Ehrlich ME.

ASN Neuro. 2011 Jun 7;3(3):e00060. doi: 10.1042/AN20110009.

PMID:
21542802
[PubMed - indexed for MEDLINE]
Free PMC Article

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