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Results: 1 to 20 of 50

1.

PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.

Sabbatino F, Wang Y, Wang X, Flaherty KT, Yu L, Pepin D, Scognamiglio G, Pepe S, Kirkwood JM, Cooper ZA, Frederick DT, Wargo JA, Ferrone S, Ferrone CR.

Oncotarget. 2014 Apr 15;5(7):1926-41.

PMID:
24732172
[PubMed - in process]
Free PMC Article
2.

Aberrant apoptotic machinery confers melanoma dual resistance to BRAF(V600E) inhibitor and immune effector cells: immunosensitization by a histone deacetylase inhibitor.

Jazirehi AR, Nazarian R, Torres-Collado AX, Economou JS.

Am J Clin Exp Immunol. 2014 Feb 27;3(1):43-56. eCollection 2014.

PMID:
24660121
[PubMed]
Free PMC Article
3.

Neoadjuvant treatment of melanoma: case reports and review.

Laks S, Brueske KA, Hsueh EC.

Exp Hematol Oncol. 2013 Nov 8;2(1):30. doi: 10.1186/2162-3619-2-30.

PMID:
24499550
[PubMed]
Free PMC Article
4.

Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations.

Ihle MA, Fassunke J, König K, Grünewald I, Schlaak M, Kreuzberg N, Tietze L, Schildhaus HU, Büttner R, Merkelbach-Bruse S.

BMC Cancer. 2014 Jan 10;14:13. doi: 10.1186/1471-2407-14-13.

PMID:
24410877
[PubMed - in process]
Free PMC Article
5.

Altered mRNA expression related to the apoptotic effect of three xanthones on human melanoma SK-MEL-28 cell line.

Wang JJ, Zhang W, Sanderson BJ.

Biomed Res Int. 2013;2013:715603. doi: 10.1155/2013/715603. Epub 2013 Sep 23.

PMID:
24175297
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

From bench to bedside: lessons learned in translating preclinical studies in cancer drug development.

Lieu CH, Tan AC, Leong S, Diamond JR, Eckhardt SG.

J Natl Cancer Inst. 2013 Oct 2;105(19):1441-56. doi: 10.1093/jnci/djt209. Epub 2013 Sep 19. Review.

PMID:
24052618
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Targeted therapy; from advanced melanoma to the adjuvant setting.

Ahn A, Eccles MR.

Front Oncol. 2013 Aug 9;3:205. doi: 10.3389/fonc.2013.00205. eCollection 2013. No abstract available.

PMID:
23951556
[PubMed]
Free PMC Article
8.

Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies.

Fattore L, Marra E, Pisanu ME, Noto A, de Vitis C, Belleudi F, Aurisicchio L, Mancini R, Torrisi MR, Ascierto PA, Ciliberto G.

J Transl Med. 2013 Jul 27;11:180. doi: 10.1186/1479-5876-11-180.

PMID:
23890105
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".

Ascierto PA, Grimaldi AM, Acquavella N, Borgognoni L, Calabrò L, Cascinelli N, Cesano A, Del Vecchio M, Eggermont AM, Faries M, Ferrone S, Fox BA, Gajewski TF, Galon J, Gnjatic S, Gogas H, Kashani-Sabet M, Kaufman HL, Larkin J, Lo RS, Mantovani A, Margolin K, Melief C, McArthur G, Palmieri G, Puzanov I, Ribas A, Seliger B, Sosman J, Suenaert P, Tarhini AA, Trinchieri G, Vidal-Vanaclocha F, Wang E, Ciliberto G, Mozzillo N, Marincola FM, Thurin M.

J Transl Med. 2013 Jun 3;11:137. doi: 10.1186/1479-5876-11-137.

PMID:
23731854
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Antitumor activity of a humanized, bivalent immunotoxin targeting fn14-positive solid tumors.

Zhou H, Hittelman WN, Yagita H, Cheung LH, Martin SS, Winkles JA, Rosenblum MG.

Cancer Res. 2013 Jul 15;73(14):4439-50. doi: 10.1158/0008-5472.CAN-13-0187. Epub 2013 May 30.

PMID:
23722548
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene.

Hall A, Meyle KD, Lange MK, Klima M, Sanderhoff M, Dahl C, Abildgaard C, Thorup K, Moghimi SM, Jensen PB, Bartek J, Guldberg P, Christensen C.

Oncotarget. 2013 Apr;4(4):584-99.

PMID:
23603840
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma.

Richter A, Grieu F, Carrello A, Amanuel B, Namdarian K, Rynska A, Lucas A, Michael V, Bell A, Fox SB, Hewitt CA, Do H, McArthur GA, Wong SQ, Dobrovic A, Iacopetta B.

Sci Rep. 2013;3:1659. doi: 10.1038/srep01659.

PMID:
23584600
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Evolving approaches to patients with advanced differentiated thyroid cancer.

Haugen BR, Sherman SI.

Endocr Rev. 2013 Jun;34(3):439-55. doi: 10.1210/er.2012-1038. Epub 2013 Apr 10. Review. Erratum in: Endocr Rev. 2013 Dec;34(6):925.

PMID:
23575762
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.

Sharma A, Madhunapantula SV, Gowda R, Berg A, Neves RI, Robertson GP.

Am J Pathol. 2013 Apr;182(4):1151-62. doi: 10.1016/j.ajpath.2012.12.019. Epub 2013 Feb 12.

PMID:
23416158
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genetics of melanoma.

Wangari-Talbot J, Chen S.

Front Genet. 2013 Jan 25;3:330. doi: 10.3389/fgene.2012.00330. eCollection 2012.

PMID:
23372575
[PubMed]
Free PMC Article
16.

Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.

Montero-Conde C, Ruiz-Llorente S, Dominguez JM, Knauf JA, Viale A, Sherman EJ, Ryder M, Ghossein RA, Rosen N, Fagin JA.

Cancer Discov. 2013 May;3(5):520-33. doi: 10.1158/2159-8290.CD-12-0531. Epub 2013 Jan 29.

PMID:
23365119
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib.

Lopez-Rios F, Angulo B, Gomez B, Mair D, Martinez R, Conde E, Shieh F, Vaks J, Langland R, Lawrence HJ, de Castro DG.

PLoS One. 2013;8(1):e53733. doi: 10.1371/journal.pone.0053733. Epub 2013 Jan 10.

PMID:
23326492
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations.

Gentilcore G, Madonna G, Mozzillo N, Ribas A, Cossu A, Palmieri G, Ascierto PA.

BMC Cancer. 2013 Jan 14;13:17. doi: 10.1186/1471-2407-13-17.

PMID:
23317446
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Functional profiling of live melanoma samples using a novel automated platform.

Schayowitz A, Bertenshaw G, Jeffries E, Schatz T, Cotton J, Villanueva J, Herlyn M, Krepler C, Vultur A, Xu W, Yu GH, Schuchter L, Clark DP.

PLoS One. 2012;7(12):e52760. doi: 10.1371/journal.pone.0052760. Epub 2012 Dec 28.

PMID:
23285177
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research.

Buck JR, Saleh S, Uddin MI, Manning HC.

Tetrahedron Lett. 2012 Aug 8;53(32):4161-4165. Epub 2012 Jun 6.

PMID:
23180892
[PubMed]
Free PMC Article

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