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Results: 12

1.

From design to screening: a new antimicrobial peptide discovery pipeline.

Guralp SA, Murgha YE, Rouillard JM, Gulari E.

PLoS One. 2013;8(3):e59305. doi: 10.1371/journal.pone.0059305. Epub 2013 Mar 19.

PMID:
23527157
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A peptide derived from phage display library exhibits antibacterial activity against E. coli and Pseudomonas aeruginosa.

Sainath Rao S, Mohan KV, Atreya CD.

PLoS One. 2013;8(2):e56081. doi: 10.1371/journal.pone.0056081. Epub 2013 Feb 11.

PMID:
23409125
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Synthetic molecular evolution of pore-forming peptides by iterative combinatorial library screening.

Krauson AJ, He J, Wimley AW, Hoffmann AR, Wimley WC.

ACS Chem Biol. 2013 Apr 19;8(4):823-31. doi: 10.1021/cb300598k. Epub 2013 Feb 20.

PMID:
23394375
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hemolytic activity of membrane-active peptides correlates with the thermodynamics of binding to 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayers.

Spaller BL, Trieu JM, Almeida PF.

J Membr Biol. 2013 Mar;246(3):257-62. doi: 10.1007/s00232-013-9525-z. Epub 2013 Jan 18.

PMID:
23329339
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening.

Krauson AJ, He J, Wimley WC.

J Am Chem Soc. 2012 Aug 1;134(30):12732-41. doi: 10.1021/ja3042004. Epub 2012 Jul 18.

PMID:
22731650
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers.

Krauson AJ, He J, Wimley WC.

Biochim Biophys Acta. 2012 Jul;1818(7):1625-32.

PMID:
22365969
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Exploring the pharmacological potential of promiscuous host-defense peptides: from natural screenings to biotechnological applications.

Silva ON, Mulder KC, Barbosa AE, Otero-Gonzalez AJ, Lopez-Abarrategui C, Rezende TM, Dias SC, Franco OL.

Front Microbiol. 2011 Nov 22;2:232. doi: 10.3389/fmicb.2011.00232. eCollection 2011.

PMID:
22125552
[PubMed]
Free PMC Article
8.

Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs.

Riedl S, Zweytick D, Lohner K.

Chem Phys Lipids. 2011 Nov;164(8):766-81. doi: 10.1016/j.chemphyslip.2011.09.004. Epub 2011 Sep 16. Review.

PMID:
21945565
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Spontaneous membrane-translocating peptides by orthogonal high-throughput screening.

Marks JR, Placone J, Hristova K, Wimley WC.

J Am Chem Soc. 2011 Jun 15;133(23):8995-9004. doi: 10.1021/ja2017416. Epub 2011 May 19.

PMID:
21545169
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Antimicrobial peptides: successes, challenges and unanswered questions.

Wimley WC, Hristova K.

J Membr Biol. 2011 Jan;239(1-2):27-34. doi: 10.1007/s00232-011-9343-0. Epub 2011 Jan 12. Review.

PMID:
21225255
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A thermodynamic approach to the mechanism of cell-penetrating peptides in model membranes.

McKeown AN, Naro JL, Huskins LJ, Almeida PF.

Biochemistry. 2011 Feb 8;50(5):654-62. doi: 10.1021/bi1013358. Epub 2011 Jan 11.

PMID:
21166473
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Describing the mechanism of antimicrobial peptide action with the interfacial activity model.

Wimley WC.

ACS Chem Biol. 2010 Oct 15;5(10):905-17. doi: 10.1021/cb1001558. Review.

PMID:
20698568
[PubMed - indexed for MEDLINE]
Free PMC Article

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