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Items: 1 to 20 of 361


Comparison of DNA Quantification Methods for Next Generation Sequencing.

Robin JD, Ludlow AT, LaRanger R, Wright WE, Shay JW.

Sci Rep. 2016 Apr 6;6:24067. doi: 10.1038/srep24067.


Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces.

Engin HB, Kreisberg JF, Carter H.

PLoS One. 2016 Apr 4;11(4):e0152929. doi: 10.1371/journal.pone.0152929. eCollection 2016.


MiRComb: An R Package to Analyse miRNA-mRNA Interactions. Examples across Five Digestive Cancers.

Vila-Casadesús M, Gironella M, Lozano JJ.

PLoS One. 2016 Mar 11;11(3):e0151127. doi: 10.1371/journal.pone.0151127. eCollection 2016.


Crambled: A Shiny application to enable intuitive resolution of conflicting cellularity estimates.

Lynch A.

F1000Res. 2015 Dec 7;4:1407. doi: 10.12688/f1000research.7453.1. eCollection 2015.


Mutation pattern is an influential factor on functional mutation rates in cancer.

Du C, Wu X, Li J.

Cancer Cell Int. 2016 Feb 9;16:2. doi: 10.1186/s12935-016-0278-5. eCollection 2015.


Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity.

Pavel AB, Sonkin D, Reddy A.

BMC Syst Biol. 2016 Feb 11;10(1):16. doi: 10.1186/s12918-016-0260-9.


Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity.

Shimada K, Hayano M, Pagano NC, Stockwell BR.

Cell Chem Biol. 2016 Feb 18;23(2):225-35. doi: 10.1016/j.chembiol.2015.11.016. Epub 2016 Feb 4.


State of the art biological therapies in pancreatic cancer.

Di Marco M, Grassi E, Durante S, Vecchiarelli S, Palloni A, Macchini M, Casadei R, Ricci C, Panzacchi R, Santini D, Biasco G.

World J Gastrointest Oncol. 2016 Jan 15;8(1):55-66. doi: 10.4251/wjgo.v8.i1.55. Review.


Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive.

Mishra S, Whetstine JR.

Mol Cell Biol. 2016 Jan 11;36(7):1050-63. doi: 10.1128/MCB.00652-15. Review.


Signaling mechanisms of bortezomib in TRAF3-deficient mouse B lymphoma and human multiple myeloma cells.

Edwards SK, Han Y, Liu Y, Kreider BZ, Liu Y, Grewal S, Desai A, Baron J, Moore CR, Luo C, Xie P.

Leuk Res. 2016 Feb;41:85-95. doi: 10.1016/j.leukres.2015.12.005. Epub 2015 Dec 19.


Leveraging big data to transform target selection and drug discovery.

Chen B, Butte AJ.

Clin Pharmacol Ther. 2016 Mar;99(3):285-97. doi: 10.1002/cpt.318.


Systematic Prioritization of Druggable Mutations in ∼5000 Genomes Across 16 Cancer Types Using a Structural Genomics-based Approach.

Zhao J, Cheng F, Wang Y, Arteaga CL, Zhao Z.

Mol Cell Proteomics. 2016 Feb;15(2):642-56. doi: 10.1074/mcp.M115.053199. Epub 2015 Dec 9.


A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S, Korshunov A, Tarpey PS, Butler AP, Hinton J, Jones D, Menzies A, Raine K, Shepherd R, Stebbings L, Teague JW, Ribeca P, Giner FC, Beltran S, Raineri E, Dabad M, Heath SC, Gut M, Denroche RE, Harding NJ, Yamaguchi TN, Fujimoto A, Nakagawa H, Quesada V, Valdés-Mas R, Nakken S, Vodák D, Bower L, Lynch AG, Anderson CL, Waddell N, Pearson JV, Grimmond SM, Peto M, Spellman P, He M, Kandoth C, Lee S, Zhang J, Létourneau L, Ma S, Seth S, Torrents D, Xi L, Wheeler DA, López-Otín C, Campo E, Campbell PJ, Boutros PC, Puente XS, Gerhard DS, Pfister SM, McPherson JD, Hudson TJ, Schlesner M, Lichter P, Eils R, Jones DT, Gut IG.

Nat Commun. 2015 Dec 9;6:10001. doi: 10.1038/ncomms10001.


On the Sample Complexity of Cancer Pathways Identification.

Vandin F, Raphael BJ, Upfal E.

J Comput Biol. 2016 Jan;23(1):30-41. doi: 10.1089/cmb.2015.0100. Epub 2015 Dec 8.


Alignment of Short Reads: A Crucial Step for Application of Next-Generation Sequencing Data in Precision Medicine.

Ye H, Meehan J, Tong W, Hong H.

Pharmaceutics. 2015 Nov 23;7(4):523-41. doi: 10.3390/pharmaceutics7040523. Review.


Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials.

Le Tourneau C, Kamal M, Tsimberidou AM, Bedard P, Pierron G, Callens C, Rouleau E, Vincent-Salomon A, Servant N, Alt M, Rouzier R, Paoletti X, Delattre O, Bièche I.

J Natl Cancer Inst. 2015 Nov 23;108(4). pii: djv362. doi: 10.1093/jnci/djv362. Print 2016 Apr. Review.


Signatures of Evolutionary Adaptation in Quantitative Trait Loci Influencing Trace Element Homeostasis in Liver.

Engelken J, Espadas G, Mancuso FM, Bonet N, Scherr AL, Jímenez-Álvarez V, Codina-Solà M, Medina-Stacey D, Spataro N, Stoneking M, Calafell F, Sabidó E, Bosch E.

Mol Biol Evol. 2016 Mar;33(3):738-54. doi: 10.1093/molbev/msv267. Epub 2015 Nov 17.

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