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Items: 1 to 20 of 60

1.

IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier.

Lee MJ, Bing SJ, Choi J, Jang M, Lee G, Lee H, Chang BS, Jee Y, Lee SJ, Cho IH.

Mol Neurodegener. 2016 Jul 22;11(1):54. doi: 10.1186/s13024-016-0116-1.

2.

GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis.

Hussman JP, Beecham AH, Schmidt M, Martin ER, McCauley JL, Vance JM, Haines JL, Pericak-Vance MA.

Genes Immun. 2016 Jul;17(5):305-12. doi: 10.1038/gene.2016.23. Epub 2016 Jun 9.

3.

The Atypical Inhibitor of NF-κB, IκBζ, Controls Macrophage Interleukin-10 Expression.

Hörber S, Hildebrand DG, Lieb WS, Lorscheid S, Hailfinger S, Schulze-Osthoff K, Essmann F.

J Biol Chem. 2016 Jun 10;291(24):12851-61. doi: 10.1074/jbc.M116.718825. Epub 2016 Apr 18.

PMID:
27129283
4.

Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells.

Meininger I, Griesbach RA, Hu D, Gehring T, Seeholzer T, Bertossi A, Kranich J, Oeckinghaus A, Eitelhuber AC, Greczmiel U, Gewies A, Schmidt-Supprian M, Ruland J, Brocker T, Heissmeyer V, Heyd F, Krappmann D.

Nat Commun. 2016 Apr 12;7:11292. doi: 10.1038/ncomms11292.

5.

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses.

Troy NM, Hollams EM, Holt PG, Bosco A.

BMC Med Genomics. 2016 Feb 27;9:9. doi: 10.1186/s12920-016-0171-z.

6.

IκBζ is a key driver in the development of psoriasis.

Johansen C, Mose M, Ommen P, Bertelsen T, Vinter H, Hailfinger S, Lorscheid S, Schulze-Osthoff K, Iversen L.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5825-33. doi: 10.1073/pnas.1509971112. Epub 2015 Oct 12.

7.

Phosphoenolpyruvate Carboxykinase, a Key Enzyme That Controls Blood Glucose, Is a Target of Retinoic Acid Receptor-Related Orphan Receptor α.

Matsuoka H, Shima A, Kuramoto D, Kikumoto D, Matsui T, Michihara A.

PLoS One. 2015 Sep 18;10(9):e0137955. doi: 10.1371/journal.pone.0137955. eCollection 2015.

8.

Chromatin Remodeling and Transcriptional Control in Innate Immunity: Emergence of Akirin2 as a Novel Player.

Tartey S, Takeuchi O.

Biomolecules. 2015 Jul 22;5(3):1618-33. doi: 10.3390/biom5031618. Review.

9.

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, Fuyuno Y, Hart A, Juyal RC, Juyal G, Kim WH, Morris AP, Poustchi H, Newman WG, Midha V, Orchard TR, Vahedi H, Sood A, Sung JJ, Malekzadeh R, Westra HJ, Yamazaki K, Yang SK; International Multiple Sclerosis Genetics Consortium; International IBD Genetics Consortium, Barrett JC, Franke A, Alizadeh BZ, Parkes M, B K T, Daly MJ, Kubo M, Anderson CA, Weersma RK.

Nat Genet. 2015 Sep;47(9):979-86. doi: 10.1038/ng.3359. Epub 2015 Jul 20.

10.

Control of IFN-γ production and regulatory function by the inducible nuclear protein IκB-ζ in T cells.

MaruYama T, Kobayashi S, Ogasawara K, Yoshimura A, Chen W, Muta T.

J Leukoc Biol. 2015 Sep;98(3):385-93. doi: 10.1189/jlb.2A0814-384R. Epub 2015 May 27.

11.

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.

Tsoi LC, Spain SL, Ellinghaus E, Stuart PE, Capon F, Knight J, Tejasvi T, Kang HM, Allen MH, Lambert S, Stoll SW, Weidinger S, Gudjonsson JE, Koks S, Kingo K, Esko T, Das S, Metspalu A, Weichenthal M, Enerback C, Krueger GG, Voorhees JJ, Chandran V, Rosen CF, Rahman P, Gladman DD, Reis A, Nair RP, Franke A, Barker JN, Abecasis GR, Trembath RC, Elder JT.

Nat Commun. 2015 May 5;6:7001. doi: 10.1038/ncomms8001.

12.

Glucocorticoid-resistant Th17 cells are selectively attenuated by cyclosporine A.

Schewitz-Bowers LP, Lait PJ, Copland DA, Chen P, Wu W, Dhanda AD, Vistica BP, Williams EL, Liu B, Jawad S, Li Z, Tucker W, Hirani S, Wakabayashi Y, Zhu J, Sen N, Conway-Campbell BL, Gery I, Dick AD, Wei L, Nussenblatt RB, Lee RW.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4080-5. doi: 10.1073/pnas.1418316112. Epub 2015 Mar 16.

14.

Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.

Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, Goldszmid R, McVicar DW, Lyakh L, Trinchieri G.

PLoS One. 2014 Dec 4;9(12):e114516. doi: 10.1371/journal.pone.0114516. eCollection 2014.

15.

The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model.

Kobayashi S, Hara A, Isagawa T, Manabe I, Takeda K, MaruYama T.

PLoS One. 2014 Oct 27;9(10):e110838. doi: 10.1371/journal.pone.0110838. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0118159.

16.

Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein IκB-ζ.

Hanihara-Tatsuzawa F, Miura H, Kobayashi S, Isagawa T, Okuma A, Manabe I, MaruYama T.

J Biol Chem. 2014 Nov 7;289(45):30925-36. doi: 10.1074/jbc.M114.553230. Epub 2014 Aug 14.

17.

Complex interactions of transcription factors in mediating cytokine biology in T cells.

Li P, Spolski R, Liao W, Leonard WJ.

Immunol Rev. 2014 Sep;261(1):141-56. doi: 10.1111/imr.12199. Review.

18.

Transcriptional and epigenetic regulation of T-helper lineage specification.

Tripathi SK, Lahesmaa R.

Immunol Rev. 2014 Sep;261(1):62-83. doi: 10.1111/imr.12204. Review.

19.

Transcriptional and epigenetic networks of helper T and innate lymphoid cells.

Shih HY, Sciumè G, Poholek AC, Vahedi G, Hirahara K, Villarino AV, Bonelli M, Bosselut R, Kanno Y, Muljo SA, O'Shea JJ.

Immunol Rev. 2014 Sep;261(1):23-49. doi: 10.1111/imr.12208. Review.

20.

Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex.

Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira S, Takeuchi O.

EMBO J. 2014 Oct 16;33(20):2332-48. doi: 10.15252/embj.201488447. Epub 2014 Aug 8.

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