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Targeting of leukemia-initiating cells in acute promyelocytic leukemia.

Testa U, Lo-Coco F.

Stem Cell Investig. 2015 Apr 29;2:8. doi: 10.3978/j.issn.2306-9759.2015.04.03. eCollection 2015. Review.


Tmc1 Is a Dynamically Regulated Effector of the Rpn4 Proteotoxic Stress Response.

Guerra-Moreno A, Hanna J.

J Biol Chem. 2016 Jul 8;291(28):14788-95. doi: 10.1074/jbc.M116.726398. Epub 2016 May 12.


Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer.

Chang KJ, Yang MH, Zheng JC, Li B, Nie W.

Am J Transl Res. 2016 Feb 15;8(2):1133-43. eCollection 2016.


Construction of a metabolomics profile of arsenic trioxide effect in gastric carcinoma cell line SGC7901.

Chen Z, Zhang H, Yang L, Jiang H, Guo S, Li Y, Tao S.

Acta Biochim Biophys Sin (Shanghai). 2016 May;48(5):474-81. doi: 10.1093/abbs/gmw022. Epub 2016 Apr 3.


Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML).

Milutinovic S, Heynen-Genel S, Chao E, Dewing A, Solano R, Milan L, Barron N, He M, Diaz PW, Matsuzawa S, Reed JC, Hassig CA.

PLoS One. 2016 Mar 31;11(3):e0152692. doi: 10.1371/journal.pone.0152692. eCollection 2016.


Role of Signal Regulatory Protein α in Arsenic Trioxide-induced Promyelocytic Leukemia Cell Apoptosis.

Pan C, Zhu D, Zhuo J, Li L, Wang D, Zhang CY, Liu Y, Zen K.

Sci Rep. 2016 Mar 24;6:23710. doi: 10.1038/srep23710.


Role of endoplasmic reticulum stress in drug-induced toxicity.

Foufelle F, Fromenty B.

Pharmacol Res Perspect. 2016 Feb 4;4(1):e00211. doi: 10.1002/prp2.211. eCollection 2016 Feb. Review.


Study of Arsenic Sulfide in Solid Tumor Cells Reveals Regulation of Nuclear Factors of Activated T-cells by PML and p53.

Ding W, Tong Y, Zhang X, Pan M, Chen S.

Sci Rep. 2016 Jan 22;6:19793. doi: 10.1038/srep19793.


ALTernative Telomere Maintenance and Cancer.

Dilley RL, Greenberg RA.

Trends Cancer. 2015 Oct 1;1(2):145-156.


Targeting Transcription Factors in Cancer.

Bhagwat AS, Vakoc CR.

Trends Cancer. 2015 Sep 1;1(1):53-65.


SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer.

Eifler K, Vertegaal AC.

Trends Biochem Sci. 2015 Dec;40(12):779-93. doi: 10.1016/j.tibs.2015.09.006. Epub 2015 Oct 22. Review.


Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic.

Zhang HN, Yang L, Ling JY, Czajkowsky DM, Wang JF, Zhang XW, Zhou YM, Ge F, Yang MK, Xiong Q, Guo SJ, Le HY, Wu SF, Yan W, Liu B, Zhu H, Chen Z, Tao SC.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15084-9. doi: 10.1073/pnas.1521316112. Epub 2015 Nov 23.


Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth.

Zhang L, Tong Y, Zhang X, Pan M, Chen S.

Drug Des Devel Ther. 2015 Oct 30;9:5851-62. doi: 10.2147/DDDT.S92943. eCollection 2015.


Identification of Arsenic Direct-Binding Proteins in Acute Promyelocytic Leukaemia Cells.

Zhang T, Lu H, Li W, Hu R, Chen Z.

Int J Mol Sci. 2015 Nov 10;16(11):26871-9. doi: 10.3390/ijms161125994.


Translational progress on tumor biomarkers.

Guo H, Zhou X, Lu Y, Xie L, Chen Q, Keller ET, Liu Q, Zhou Q, Zhang J.

Thorac Cancer. 2015 Nov;6(6):665-71. doi: 10.1111/1759-7714.12294. Epub 2015 Jul 27. Review.


The function, regulation and therapeutic implications of the tumor suppressor protein, PML.

Guan D, Kao HY.

Cell Biosci. 2015 Nov 4;5:60. doi: 10.1186/s13578-015-0051-9. eCollection 2015. Review.


Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth.

Zhou W, Cheng L, Shi Y, Ke SQ, Huang Z, Fang X, Chu CW, Xie Q, Bian XW, Rich JN, Bao S.

Oncotarget. 2015 Nov 10;6(35):37300-15. doi: 10.18632/oncotarget.5836.


Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response.

Guerra-Moreno A, Isasa M, Bhanu MK, Waterman DP, Eapen VV, Gygi SP, Hanna J.

J Biol Chem. 2015 Dec 11;290(50):29695-706. doi: 10.1074/jbc.M115.684969. Epub 2015 Oct 21.


Arsenic Trioxide Reduces Global Histone H4 Acetylation at Lysine 16 through Direct Binding to Histone Acetyltransferase hMOF in Human Cells.

Liu D, Wu D, Zhao L, Yang Y, Ding J, Dong L, Hu L, Wang F, Zhao X, Cai Y, Jin J.

PLoS One. 2015 Oct 16;10(10):e0141014. doi: 10.1371/journal.pone.0141014. eCollection 2015.

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