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CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism.

Yang Y, Ran J, Sun L, Sun X, Luo Y, Yan B, Tala, Liu M, Li D, Zhang L, Bao G, Zhou J.

Theranostics. 2015 Mar 2;5(7):656-66. doi: 10.7150/thno.10844. eCollection 2015.


Aging and uremia: Is there cellular and molecular crossover?

White WE, Yaqoob MM, Harwood SM.

World J Nephrol. 2015 Feb 6;4(1):19-30. doi: 10.5527/wjn.v4.i1.19. Review.


Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia.

Yuan N, Song L, Lin W, Cao Y, Xu F, Liu S, Zhang A, Wang Z, Li X, Fang Y, Zhang H, Zhao W, Hu S, Wang J, Zhang S.

Blood Cancer J. 2015 Jan 23;5:e274. doi: 10.1038/bcj.2014.96.


Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate.

Schwartz-Roberts JL, Cook KL, Chen C, Shajahan-Haq AN, Axelrod M, Wärri A, Riggins RB, Jin L, Haddad BR, Kallakury BV, Baumann WT, Clarke R.

Cancer Res. 2015 Mar 15;75(6):1046-55. doi: 10.1158/0008-5472.CAN-14-1851. Epub 2015 Jan 9.


Autophagy in the physiology and pathology of the central nervous system.

Nikoletopoulou V, Papandreou ME, Tavernarakis N.

Cell Death Differ. 2015 Mar;22(3):398-407. doi: 10.1038/cdd.2014.204. Epub 2014 Dec 19. Review.


Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.

Boutter J, Huang Y, Marovca B, Vonderheit A, Grotzer MA, Eckert C, Cario G, Wollscheid B, Horvath P, Bornhauser BC, Bourquin JP.

Oncotarget. 2014 Nov 30;5(22):11501-12.


Autosis and autophagic cell death: the dark side of autophagy.

Liu Y, Levine B.

Cell Death Differ. 2015 Mar;22(3):367-76. doi: 10.1038/cdd.2014.143. Epub 2014 Sep 26. Review.


Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics.

Evangelisti C, Evangelisti C, Teti G, Chiarini F, Falconi M, Melchionda F, Pession A, Bertaina A, Locatelli F, McCubrey JA, Beak DJ, Bittman R, Pyne S, Pyne NJ, Martelli AM.

Oncotarget. 2014 Sep 15;5(17):7886-901.


A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis.

Chen S, Zhang Y, Zhou L, Leng Y, Lin H, Kmieciak M, Pei XY, Jones R, Orlowski RZ, Dai Y, Grant S.

Blood. 2014 Oct 23;124(17):2687-97. doi: 10.1182/blood-2014-03-564534. Epub 2014 Sep 10.


Taking aim at Alzheimer's disease through the mammalian target of rapamycin.

Maiese K.

Ann Med. 2014 Dec;46(8):587-96. doi: 10.3109/07853890.2014.941921. Epub 2014 Aug 8.


Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.

Mizumura K, Cloonan SM, Nakahira K, Bhashyam AR, Cervo M, Kitada T, Glass K, Owen CA, Mahmood A, Washko GR, Hashimoto S, Ryter SW, Choi AM.

J Clin Invest. 2014 Sep;124(9):3987-4003. doi: 10.1172/JCI74985. Epub 2014 Aug 1.


Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts.

Suryani S, Carol H, Chonghaile TN, Frismantas V, Sarmah C, High L, Bornhauser B, Cowley MJ, Szymanska B, Evans K, Boehm I, Tonna E, Jones L, Manesh DM, Kurmasheva RT, Billups C, Kaplan W, Letai A, Bourquin JP, Houghton PJ, Smith MA, Lock RB.

Clin Cancer Res. 2014 Sep 1;20(17):4520-31. doi: 10.1158/1078-0432.CCR-14-0259. Epub 2014 Jul 10.


Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik.

Chen S, Zhou L, Zhang Y, Leng Y, Pei XY, Lin H, Jones R, Orlowski RZ, Dai Y, Grant S.

Mol Cell Biol. 2014 Sep 15;34(18):3435-49. doi: 10.1128/MCB.01383-13. Epub 2014 Jul 7.


Human cancer growth and therapy in immunodeficient mouse models.

Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL.

Cold Spring Harb Protoc. 2014 Jul 1;2014(7):694-708. doi: 10.1101/pdb.top073585. Review.


RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.

Su JC, Tseng PH, Hsu CY, Tai WT, Huang JW, Ko CH, Lin MW, Liu CY, Chen KF, Shiau CW.

Oncotarget. 2014 Jul 15;5(13):4909-19.


Mcl-1 ubiquitination: unique regulation of an essential survival protein.

Mojsa B, Lassot I, Desagher S.

Cells. 2014 May 8;3(2):418-37. doi: 10.3390/cells3020418.


Cutting through the complexities of mTOR for the treatment of stroke.

Maiese K.

Curr Neurovasc Res. 2014 May;11(2):177-86. Review.


The impact of autophagy on cell death modalities.

Ryter SW, Mizumura K, Choi AM.

Int J Cell Biol. 2014;2014:502676. doi: 10.1155/2014/502676. Epub 2014 Feb 4. Review.


Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?

Brinkmann K, Kashkar H.

Cell Death Dis. 2014 Mar 6;5:e1098. doi: 10.1038/cddis.2014.61. Review.

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