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Results: 1 to 20 of 49

1.

PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence.

Hayashi-Takagi A, Araki Y, Nakamura M, Vollrath B, Duron SG, Yan Z, Kasai H, Huganir RL, Campbell DA, Sawa A.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6461-6. doi: 10.1073/pnas.1321109111. Epub 2014 Apr 3.

PMID:
24706880
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Involvement of genetic and environmental factors in the onset of depression.

Nabeshima T, Kim HC.

Exp Neurobiol. 2013 Dec;22(4):235-43. doi: 10.5607/en.2013.22.4.235. Epub 2013 Dec 31. Review.

PMID:
24465138
[PubMed]
Free PMC Article
3.

Developmental origins of brain disorders: roles for dopamine.

Money KM, Stanwood GD.

Front Cell Neurosci. 2013 Dec 19;7:260. doi: 10.3389/fncel.2013.00260. Review.

PMID:
24391541
[PubMed]
Free PMC Article
4.

Schizophrenia: an integrated sociodevelopmental-cognitive model.

Howes OD, Murray RM.

Lancet. 2014 May 10;383(9929):1677-87. doi: 10.1016/S0140-6736(13)62036-X. Epub 2013 Dec 6. Review.

PMID:
24315522
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction.

Gamo NJ, Duque A, Paspalas CD, Kata A, Fine R, Boven L, Bryan C, Lo T, Anighoro K, Bermudez L, Peng K, Annor A, Raja A, Mansson E, Taylor SR, Patel K, Simen AA, Arnsten AF.

Transl Psychiatry. 2013 Dec 3;3:e328. doi: 10.1038/tp.2013.104.

PMID:
24301646
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice.

Lee FH, Zai CC, Cordes SP, Roder JC, Wong AH.

Mol Brain. 2013 Apr 30;6:20. doi: 10.1186/1756-6606-6-20.

PMID:
23631734
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Development and specification of GABAergic cortical interneurons.

Kelsom C, Lu W.

Cell Biosci. 2013 Apr 23;3(1):19. doi: 10.1186/2045-3701-3-19.

PMID:
23618463
[PubMed]
Free PMC Article
8.

DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.

Soda T, Frank C, Ishizuka K, Baccarella A, Park YU, Flood Z, Park SK, Sawa A, Tsai LH.

Mol Psychiatry. 2013 Aug;18(8):898-908. doi: 10.1038/mp.2013.38. Epub 2013 Apr 16.

PMID:
23587879
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

DISC1 genetics, biology and psychiatric illness.

Thomson PA, Malavasi EL, Grünewald E, Soares DC, Borkowska M, Millar JK.

Front Biol (Beijing). 2013 Feb 1;8(1):1-31.

PMID:
23550053
[PubMed]
Free PMC Article
10.

NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia.

Snyder MA, Gao WJ.

Front Cell Neurosci. 2013 Mar 27;7:31. doi: 10.3389/fncel.2013.00031. eCollection 2013.

PMID:
23543703
[PubMed]
Free PMC Article
11.

Synapse-specific contributions in the cortical pathology of schizophrenia.

Seshadri S, Zeledon M, Sawa A.

Neurobiol Dis. 2013 May;53:26-35. doi: 10.1016/j.nbd.2013.01.009. Epub 2013 Jan 18. Review.

PMID:
23336981
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging.

Jaaro-Peled H, Niwa M, Foss CA, Murai R, de Los Reyes S, Kamiya A, Mateo Y, O'Donnell P, Cascella NG, Nabeshima T, Guilarte TR, Pomper MG, Sawa A.

Hum Mol Genet. 2013 Apr 15;22(8):1574-80. doi: 10.1093/hmg/ddt007. Epub 2013 Jan 11.

PMID:
23314019
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

DISC1: a key lead in studying cortical development and associated brain disorders.

Narayan S, Nakajima K, Sawa A.

Neuroscientist. 2013 Oct;19(5):451-64. doi: 10.1177/1073858412470168. Epub 2013 Jan 8. Review.

PMID:
23300216
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A structure-function mechanism for schizophrenia.

Vadakkan KI.

Front Psychiatry. 2012 Dec 28;3:108. doi: 10.3389/fpsyt.2012.00108. eCollection 2012.

PMID:
23293606
[PubMed]
Free PMC Article
15.

Losing your inhibition: linking cortical GABAergic interneurons to schizophrenia.

Inan M, Petros TJ, Anderson SA.

Neurobiol Dis. 2013 May;53:36-48. doi: 10.1016/j.nbd.2012.11.013. Epub 2012 Nov 29. Review.

PMID:
23201207
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Effects of antipsychotics on dentate gyrus stem cell proliferation and survival in animal models: a critical update.

Keilhoff G, Fusar-Poli P, Becker A.

Neural Plast. 2012;2012:832757. doi: 10.1155/2012/832757. Epub 2012 Oct 24. Review.

PMID:
23150836
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

DISC1 as a therapeutic target for mental illnesses.

Hikida T, Gamo NJ, Sawa A.

Expert Opin Ther Targets. 2012 Dec;16(12):1151-60. doi: 10.1517/14728222.2012.719879. Epub 2012 Nov 6. Review.

PMID:
23130881
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1.

Kivimäe S, Martin PM, Kapfhamer D, Ruan Y, Heberlein U, Rubenstein JL, Cheyette BN.

Transl Psychiatry. 2011 Sep 27;1:e43. doi: 10.1038/tp.2011.41.

PMID:
22832659
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Neural activations during auditory oddball processing discriminating schizophrenia and psychotic bipolar disorder.

Ethridge LE, Hamm JP, Shapiro JR, Summerfelt AT, Keedy SK, Stevens MC, Pearlson G, Tamminga CA, Boutros NN, Sweeney JA, Keshavan MS, Thaker G, Clementz BA.

Biol Psychiatry. 2012 Nov 1;72(9):766-74. doi: 10.1016/j.biopsych.2012.03.034. Epub 2012 May 8.

PMID:
22572033
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Disrupted-in-schizophrenia (DISC1) functions presynaptically at glutamatergic synapses.

Maher BJ, LoTurco JJ.

PLoS One. 2012;7(3):e34053. doi: 10.1371/journal.pone.0034053. Epub 2012 Mar 30.

PMID:
22479520
[PubMed - indexed for MEDLINE]
Free PMC Article

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