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Items: 20

1.

Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D.

Zhu Y, He Q, Aydin C, Rubera I, Tauc M, Chen M, Weinstein LS, Marshansky V, Jüppner H, Bastepe M.

Endocrinology. 2016 Feb;157(2):497-507. doi: 10.1210/en.2015-1639. Epub 2015 Dec 15.

PMID:
26671181
2.

Treatment of chronic kidney diseases with histone deacetylase inhibitors.

Liu N, Zhuang S.

Front Physiol. 2015 Apr 28;6:121. doi: 10.3389/fphys.2015.00121. eCollection 2015. Review.

3.

Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis?

Tran PV, Sharma M, Li X, Calvet JP.

Birth Defects Res C Embryo Today. 2014 Jun;102(2):159-73. doi: 10.1002/bdrc.21065. Epub 2014 May 26. Review.

4.

Role of PKD2 in rheotaxis in Dictyostelium.

Lima WC, Vinet A, Pieters J, Cosson P.

PLoS One. 2014 Feb 10;9(2):e88682. doi: 10.1371/journal.pone.0088682. eCollection 2014. Erratum in: PLoS One. 2014;9(2):e91457.

5.

Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease.

Park EY, Kim BH, Lee EJ, Chang E, Kim DW, Choi SY, Park JH.

J Biol Chem. 2014 Mar 28;289(13):9254-62. doi: 10.1074/jbc.M113.514166. Epub 2014 Feb 10.

6.

Experimental therapies and ongoing clinical trials to slow down progression of ADPKD.

Irazabal MV, Torres VE.

Curr Hypertens Rev. 2013 Feb;9(1):44-59. Review.

7.

New treatments for autosomal dominant polycystic kidney disease.

Chang MY, Ong AC.

Br J Clin Pharmacol. 2013 Oct;76(4):524-35. doi: 10.1111/bcp.12136. Review.

8.

Inhibition of Comt with tolcapone slows progression of polycystic kidney disease in the more severely affected PKD/Mhm (cy/+) substrain of the Hannover Sprague-Dawley rat.

Boehn SN, Spahn S, Neudecker S, Keppler A, Bihoreau MT, Kränzlin B, Pandey P, Hoffmann SC, Li L, Torres VE, Gröne HJ, Gretz N.

Nephrol Dial Transplant. 2013 Aug;28(8):2045-58. doi: 10.1093/ndt/gft014. Epub 2013 Mar 29.

9.

Proximal tubule-dominant transfer of AT(1a) receptors induces blood pressure responses to intracellular angiotensin II in AT(1a) receptor-deficient mice.

Li XC, Zhuo JL.

Am J Physiol Regul Integr Comp Physiol. 2013 Apr 15;304(8):R588-98. doi: 10.1152/ajpregu.00338.2012. Epub 2013 Feb 20.

10.

HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.

Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X.

PLoS One. 2012;7(11):e49418. doi: 10.1371/journal.pone.0049418. Epub 2012 Nov 13.

11.

HDAC inhibitors in kidney development and disease.

Brilli LL, Swanhart LM, de Caestecker MP, Hukriede NA.

Pediatr Nephrol. 2013 Oct;28(10):1909-21. doi: 10.1007/s00467-012-2320-8. Epub 2012 Oct 7. Review.

12.

Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1.

Foy RL, Chitalia VC, Panchenko MV, Zeng L, Lopez D, Lee JW, Rana SV, Boletta A, Qian F, Tsiokas L, Piontek KB, Germino GG, Zhou MI, Cohen HT.

Hum Mol Genet. 2012 Dec 15;21(26):5456-71. doi: 10.1093/hmg/dds391. Epub 2012 Sep 21.

13.

The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies.

Pan J, Seeger-Nukpezah T, Golemis EA.

Cell Mol Life Sci. 2013 Jun;70(11):1849-74. doi: 10.1007/s00018-012-1052-z. Epub 2012 Jul 11. Review.

14.

Dimerization is necessary for MIM-mediated membrane deformation and endocytosis.

Cao M, Zhan T, Ji M, Zhan X.

Biochem J. 2012 Sep 15;446(3):469-75. doi: 10.1042/BJ20120329.

15.

Mice deficient in MIM expression are predisposed to lymphomagenesis.

Yu D, Zhan XH, Zhao XF, Williams MS, Carey GB, Smith E, Scott D, Zhu J, Guo Y, Cherukuri S, Civin CI, Zhan X.

Oncogene. 2012 Jul 26;31(30):3561-8. doi: 10.1038/onc.2011.509. Epub 2011 Nov 14.

16.

Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation.

Fan LX, Li X, Magenheimer B, Calvet JP, Li X.

Kidney Int. 2012 Jan;81(1):76-85. doi: 10.1038/ki.2011.296. Epub 2011 Sep 7.

17.

Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin.

Reif GA, Yamaguchi T, Nivens E, Fujiki H, Pinto CS, Wallace DP.

Am J Physiol Renal Physiol. 2011 Nov;301(5):F1005-13. doi: 10.1152/ajprenal.00243.2011. Epub 2011 Aug 3.

18.

Polycystic kidney disease: pathogenesis and potential therapies.

Takiar V, Caplan MJ.

Biochim Biophys Acta. 2011 Oct;1812(10):1337-43. doi: 10.1016/j.bbadis.2010.11.014. Epub 2010 Dec 10. Review.

19.

Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase.

Flores D, Battini L, Gusella GL, Rohatgi R.

Nephron Physiol. 2011;117(4):p27-36. doi: 10.1159/000321640. Epub 2010 Nov 23.

20.

Epigenetics and autosomal dominant polycystic kidney disease.

Li X.

Biochim Biophys Acta. 2011 Oct;1812(10):1213-8. doi: 10.1016/j.bbadis.2010.10.008. Epub 2010 Oct 20. Review.

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