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Results: 1 to 20 of 80

1.

Active-state model of a dopamine D2 receptor-Gαi complex stabilized by aripiprazole-type partial agonists.

Kling RC, Tschammer N, Lanig H, Clark T, Gmeiner P.

PLoS One. 2014 Jun 16;9(6):e100069. doi: 10.1371/journal.pone.0100069. eCollection 2014.

PMID:
24932547
[PubMed - in process]
Free PMC Article
2.

Development of Fluorescent Ligands for the Human 5-HT1A Receptor.

Alonso D, Vázquez-Villa H, Gamo AM, Martínez-Esperón MF, Tortosa M, Viso A, Fernández de la Pradilla R, Junquera E, Aicart E, Martín-Fontecha M, Benhamú B, López-Rodríguez ML, Ortega-Gutiérrez S.

ACS Med Chem Lett. 2010 May 14;1(6):249-53. doi: 10.1021/ml100053y. eCollection 2010 Sep 9.

PMID:
24900203
[PubMed]
Free PMC Article
3.

Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.

Ernst OP, Lodowski DT, Elstner M, Hegemann P, Brown LS, Kandori H.

Chem Rev. 2014 Jan 8;114(1):126-63. doi: 10.1021/cr4003769. Epub 2013 Dec 23. Review. No abstract available.

PMID:
24364740
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Effect of intracellular loop 3 on intrinsic dynamics of human β2-adrenergic receptor.

Ozcan O, Uyar A, Doruker P, Akten ED.

BMC Struct Biol. 2013 Nov 9;13:29. doi: 10.1186/1472-6807-13-29.

PMID:
24206668
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Identification of a single amino acid in GluN1 that is critical for glycine-primed internalization of NMDA receptors.

Han L, Campanucci VA, Cooke J, Salter MW.

Mol Brain. 2013 Aug 13;6:36. doi: 10.1186/1756-6606-6-36.

PMID:
23941530
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Computational study on the different ligands induced conformation change of β2 adrenergic receptor-Gs protein complex.

Bai Q, Zhang Y, Ban Y, Liu H, Yao X.

PLoS One. 2013 Jul 29;8(7):e68138. doi: 10.1371/journal.pone.0068138. Print 2013.

PMID:
23922653
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics.

Tikhonova IG, Selvam B, Ivetac A, Wereszczynski J, McCammon JA.

Biochemistry. 2013 Aug 20;52(33):5593-603. doi: 10.1021/bi400499n. Epub 2013 Aug 7.

PMID:
23879802
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Novel yeast-based strategy unveils antagonist binding regions on the nuclear xenobiotic receptor PXR.

Li H, Redinbo MR, Venkatesh M, Ekins S, Chaudhry A, Bloch N, Negassa A, Mukherjee P, Kalpana G, Mani S.

J Biol Chem. 2013 May 10;288(19):13655-68. doi: 10.1074/jbc.M113.455485. Epub 2013 Mar 22.

PMID:
23525103
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Towards improved quality of GPCR models by usage of multiple templates and profile-profile comparison.

Latek D, Pasznik P, Carlomagno T, Filipek S.

PLoS One. 2013;8(2):e56742. doi: 10.1371/journal.pone.0056742. Epub 2013 Feb 28.

PMID:
23468878
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Novel insights into CB1 cannabinoid receptor signaling: a key interaction identified between the extracellular-3 loop and transmembrane helix 2.

Marcu J, Shore DM, Kapur A, Trznadel M, Makriyannis A, Reggio PH, Abood ME.

J Pharmacol Exp Ther. 2013 May;345(2):189-97. doi: 10.1124/jpet.112.201046. Epub 2013 Feb 20.

PMID:
23426954
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode.

Fillion D, Cabana J, Guillemette G, Leduc R, Lavigne P, Escher E.

J Biol Chem. 2013 Mar 22;288(12):8187-97. doi: 10.1074/jbc.M112.442053. Epub 2013 Feb 5.

PMID:
23386604
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The quiet renaissance of protein nuclear magnetic resonance.

Barrett PJ, Chen J, Cho MK, Kim JH, Lu Z, Mathew S, Peng D, Song Y, Van Horn WD, Zhuang T, Sönnichsen FD, Sanders CR.

Biochemistry. 2013 Feb 26;52(8):1303-20. doi: 10.1021/bi4000436. Epub 2013 Feb 12. Review.

PMID:
23368985
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.

Müller A, Kleinau G, Piechowski CL, Müller TD, Finan B, Pratzka J, Grüters A, Krude H, Tschöp M, Biebermann H.

PLoS One. 2013;8(1):e53347. doi: 10.1371/journal.pone.0053347. Epub 2013 Jan 15.

PMID:
23335960
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes.

Isin B, Estiu G, Wiest O, Oltvai ZN.

PLoS One. 2012;7(12):e50186. doi: 10.1371/journal.pone.0050186. Epub 2012 Dec 31.

PMID:
23300522
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations.

Yuan S, Ghoshdastider U, Trzaskowski B, Latek D, Debinski A, Pulawski W, Wu R, Gerke V, Filipek S.

PLoS One. 2012;7(11):e47114. doi: 10.1371/journal.pone.0047114. Epub 2012 Nov 26.

PMID:
23189124
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Conopeptide ρ-TIA defines a new allosteric site on the extracellular surface of the α1B-adrenoceptor.

Ragnarsson L, Wang CI, Andersson Å, Fajarningsih D, Monks T, Brust A, Rosengren KJ, Lewis RJ.

J Biol Chem. 2013 Jan 18;288(3):1814-27. doi: 10.1074/jbc.M112.430785. Epub 2012 Nov 26.

PMID:
23184947
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Restoration of renal function by a novel prostaglandin EP4 receptor-derived peptide in models of acute renal failure.

Leduc M, Hou X, Hamel D, Sanchez M, Quiniou C, Honoré JC, Roy O, Madaan A, Lubell W, Varma DR, Mancini J, Duhamel F, Peri KG, Pichette V, Heveker N, Chemtob S.

Am J Physiol Regul Integr Comp Physiol. 2013 Jan 1;304(1):R10-22. doi: 10.1152/ajpregu.00138.2012. Epub 2012 Nov 14.

PMID:
23152113
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Structure-function of the G protein-coupled receptor superfamily.

Katritch V, Cherezov V, Stevens RC.

Annu Rev Pharmacol Toxicol. 2013;53:531-56. doi: 10.1146/annurev-pharmtox-032112-135923. Epub 2012 Nov 8. Review.

PMID:
23140243
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor.

Unal H, Jagannathan R, Bhatnagar A, Tirupula K, Desnoyer R, Karnik SS.

J Biol Chem. 2013 Jan 4;288(1):540-51. doi: 10.1074/jbc.M112.392514. Epub 2012 Nov 8.

PMID:
23139413
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

β2-Adrenergic receptor solutions for structural biology analyzed with microscale NMR diffusion measurements.

Horst R, Stanczak P, Stevens RC, Wüthrich K.

Angew Chem Int Ed Engl. 2013 Jan 2;52(1):331-5. doi: 10.1002/anie.201205474. Epub 2012 Oct 24.

PMID:
23097212
[PubMed - indexed for MEDLINE]
Free PMC Article

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