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Functional test of PCDHB11, the most human-specific neuronal surface protein.

de Freitas GB, Gonçalves RA, Gralle M.

BMC Evol Biol. 2016 Apr 12;16:75. doi: 10.1186/s12862-016-0652-x.


Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.

Taberlay PC, Achinger-Kawecka J, Lun AT, Buske FA, Sabir K, Gould CM, Zotenko E, Bert SA, Giles KA, Bauer DC, Smyth GK, Stirzaker C, O'Donoghue SI, Clark SJ.

Genome Res. 2016 Jun;26(6):719-31. doi: 10.1101/gr.201517.115. Epub 2016 Apr 6.


Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer.

Timofeeva MN, Kinnersley B, Farrington SM, Whiffin N, Palles C, Svinti V, Lloyd A, Gorman M, Ooi LY, Hosking F, Barclay E, Zgaga L, Dobbins S, Martin L, Theodoratou E, Broderick P, Tenesa A, Smillie C, Grimes G, Hayward C, Campbell A, Porteous D, Deary IJ, Harris SE, Northwood EL, Barrett JH, Smith G, Wolf R, Forman D, Morreau H, Ruano D, Tops C, Wijnen J, Schrumpf M, Boot A, Vasen HF, Hes FJ, van Wezel T, Franke A, Lieb W, Schafmayer C, Hampe J, Buch S, Propping P, Hemminki K, Försti A, Westers H, Hofstra R, Pinheiro M, Pinto C, Teixeira M, Ruiz-Ponte C, Fernández-Rozadilla C, Carracedo A, Castells A, Castellví-Bel S, Campbell H, Bishop DT, Tomlinson IP, Dunlop MG, Houlston RS.

Sci Rep. 2015 Nov 10;5:16286. doi: 10.1038/srep16286.


LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.

Vieira GC, Chockalingam S, Melegh Z, Greenhough A, Malik S, Szemes M, Park JH, Kaidi A, Zhou L, Catchpoole D, Morgan R, Bates DO, Gabb PD, Malik K.

Oncotarget. 2015 Nov 24;6(37):40053-67. doi: 10.18632/oncotarget.5548.


Comparison of genomic DNA methylation pattern among septic and non-septic newborns - An epigenome wide association study.

Dhas DB, Ashmi AH, Bhat BV, Kalaivani S, Parija SC.

Genom Data. 2014 Nov 15;3:36-40. doi: 10.1016/j.gdata.2014.11.004. eCollection 2015 Mar.


Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer.

Rafique S, Thomas JS, Sproul D, Bickmore WA.

Genome Biol. 2015 Aug 3;16:145. doi: 10.1186/s13059-015-0719-9.


Symmetrical Dose-Dependent DNA-Methylation Profiles in Children with Deletion or Duplication of 7q11.23.

Strong E, Butcher DT, Singhania R, Mervis CB, Morris CA, De Carvalho D, Weksberg R, Osborne LR.

Am J Hum Genet. 2015 Aug 6;97(2):216-27. doi: 10.1016/j.ajhg.2015.05.019. Epub 2015 Jul 9.


Epigenetic-Mediated Downregulation of μ-Protocadherin in Colorectal Tumours.

Bujko M, Kober P, Statkiewicz M, Mikula M, Ligaj M, Zwierzchowski L, Ostrowski J, Siedlecki JA.

Gastroenterol Res Pract. 2015;2015:317093. doi: 10.1155/2015/317093. Epub 2015 Apr 20.


Urothelial cancer gene regulatory networks inferred from large-scale RNAseq, Bead and Oligo gene expression data.

de Matos Simoes R, Dalleau S, Williamson KE, Emmert-Streib F.

BMC Syst Biol. 2015 May 14;9:21. doi: 10.1186/s12918-015-0165-z.


Protocadherins branch out: Multiple roles in dendrite development.

Keeler AB, Molumby MJ, Weiner JA.

Cell Adh Migr. 2015;9(3):214-26. doi: 10.1080/19336918.2014.1000069. Epub 2015 Apr 14. Review.


Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer.

Jadhav RR, Ye Z, Huang RL, Liu J, Hsu PY, Huang YW, Rangel LB, Lai HC, Roa JC, Kirma NB, Huang TH, Jin VX.

Clin Epigenetics. 2015 Feb 24;7:13. doi: 10.1186/s13148-015-0045-9. eCollection 2015.


Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour.

Charlton J, Williams RD, Sebire NJ, Popov S, Vujanic G, Chagtai T, Alcaide-German M, Morris T, Butcher LM, Guilhamon P, Beck S, Pritchard-Jones K.

Genome Med. 2015 Feb 2;7(1):11. doi: 10.1186/s13073-015-0136-4. eCollection 2015.


The yin and yang of kidney development and Wilms' tumors.

Hohenstein P, Pritchard-Jones K, Charlton J.

Genes Dev. 2015 Mar 1;29(5):467-82. doi: 10.1101/gad.256396.114. Review.


The IGF signalling pathway in Wilms tumours--a report from the ENCCA Renal Tumours Biology-driven drug development workshop.

Maschietto M, Charlton J, Perotti D, Radice P, Geller JI, Pritchard-Jones K, Weeks M.

Oncotarget. 2014 Sep 30;5(18):8014-26.


Global methylation silencing of clustered proto-cadherin genes in cervical cancer: serving as diagnostic markers comparable to HPV.

Wang KH, Lin CJ, Liu CJ, Liu DW, Huang RL, Ding DC, Weng CF, Chu TY.

Cancer Med. 2015 Jan;4(1):43-55. doi: 10.1002/cam4.335. Epub 2014 Nov 21.


Expansion of stochastic expression repertoire by tandem duplication in mouse Protocadherin-α cluster.

Kaneko R, Abe M, Hirabayashi T, Uchimura A, Sakimura K, Yanagawa Y, Yagi T.

Sci Rep. 2014 Sep 2;4:6263. doi: 10.1038/srep06263.


Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood.

Charlton J, Williams RD, Weeks M, Sebire NJ, Popov S, Vujanic G, Mifsud W, Alcaide-German M, Butcher LM, Beck S, Pritchard-Jones K.

Genome Biol. 2014 Aug 19;15(8):434. doi: 10.1186/s13059-014-0434-y.


Genetic alterations of chromosomes, p53 and p16 genes in low- and high-grade bladder cancer.

Abat D, Demirhan O, Inandiklioglu N, Tunc E, Erdogan S, Tastemir D, Uslu IN, Tansug Z.

Oncol Lett. 2014 Jul;8(1):25-32. Epub 2014 May 2.


High frequency of rare variants with a moderate-to-high predicted biological effect in protocadherin genes of extremely obese.

Mariman EC, Bouwman FG, Aller EE, van Baak MA, Wang P.

Genes Nutr. 2014 May;9(3):399. doi: 10.1007/s12263-014-0399-1. Epub 2014 Mar 30.

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