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Items: 13


Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen.

Fannin RD, Gerrish K, Sieber SO, Bushel PR, Watkins PB, Paules RS.

Clin Pharmacol Ther. 2016 Apr;99(4):432-41. doi: 10.1002/cpt.328. Epub 2016 Feb 22.


Predose and Postdose Blood Gene Expression Profiles Identify the Individuals Susceptible to Acetaminophen-Induced Liver Injury in Rats.

Lu X, Hu B, Zheng J, Ji C, Fan X, Gao Y.

PLoS One. 2015 Oct 29;10(10):e0141750. doi: 10.1371/journal.pone.0141750. eCollection 2015.


Translational biomarkers of acetaminophen-induced acute liver injury.

Beger RD, Bhattacharyya S, Yang X, Gill PS, Schnackenberg LK, Sun J, James LP.

Arch Toxicol. 2015 Sep;89(9):1497-522. doi: 10.1007/s00204-015-1519-4. Epub 2015 May 17. Review.


Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity.

Sun J, Slavov S, Schnackenberg LK, Ando Y, Greenhaw J, Yang X, Salminen W, Mendrick DL, Beger R.

Comput Struct Biotechnol J. 2014 Aug 9;10(17):78-89. doi: 10.1016/j.csbj.2014.08.001. eCollection 2014 Jul.


The importance of the ionic product for water to understand the physiology of the acid-base balance in humans.

Adeva-Andany MM, Carneiro-Freire N, Donapetry-García C, Rañal-Muíño E, López-Pereiro Y.

Biomed Res Int. 2014;2014:695281. doi: 10.1155/2014/695281. Epub 2014 Apr 30. Review.


Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues.

Shchepin RV, Liu W, Yin H, Zagol-Ikapitte I, Amin T, Jeong BS, Roberts LJ 2nd, Oates JA, Porter NA, Boutaud O.

ACS Med Chem Lett. 2013 Aug 8;4(8):710-714.


Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.

Fontana RJ.

Gastroenterology. 2014 Apr;146(4):914-28. doi: 10.1053/j.gastro.2013.12.032. Epub 2013 Dec 31. Review.


Blood transcriptomics: applications in toxicology.

Joseph P, Umbright C, Sellamuthu R.

J Appl Toxicol. 2013 Nov;33(11):1193-202. doi: 10.1002/jat.2861. Epub 2013 Mar 1. Review.


The proper use of acetaminophen.

James L, Sullivan JE, Roberts D.

Paediatr Child Health. 2011 Nov;16(9):544-7.


Identification of Identical Transcript Changes in Liver and Whole Blood during Acetaminophen Toxicity.

Zhang L, Bushel PR, Chou J, Zhou T, Watkins PB.

Front Genet. 2012 Sep 4;3:162. doi: 10.3389/fgene.2012.00162. eCollection 2012.


Identification and characterization of adverse effects in 21st century toxicology.

Keller DA, Juberg DR, Catlin N, Farland WH, Hess FG, Wolf DC, Doerrer NG.

Toxicol Sci. 2012 Apr;126(2):291-7. doi: 10.1093/toxsci/kfr350. Epub 2012 Jan 19.


Understanding lactic acidosis in paracetamol (acetaminophen) poisoning.

Shah AD, Wood DM, Dargan PI.

Br J Clin Pharmacol. 2011 Jan;71(1):20-8. doi: 10.1111/j.1365-2125.2010.03765.x.


Use of transcriptomics in understanding mechanisms of drug-induced toxicity.

Cui Y, Paules RS.

Pharmacogenomics. 2010 Apr;11(4):573-85. doi: 10.2217/pgs.10.37. Review.

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